Scientists probe the brain's decision-making circuitry one neuron at a time

NCT ID NCT06489561

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Cedars-Sinai Medical Center Source: ClinicalTrials.gov ↗

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This study aims to understand how the human brain makes goal-directed decisions by recording activity from individual neurons. Researchers will monitor brain cell firing in people with epilepsy who are already undergoing invasive monitoring. Participants perform simple button-pressing tasks while their neuronal activity is recorded, helping to map the neural computations behind decision-making.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If this works, it could point toward better treatments for disorders of decision-making and performance monitoring.
What could go wrong: This is a small, early-stage observational study in a specific patient group, so findings may not apply to the general population.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Drug Resistant Epilepsy epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EPILEPSY INTRACTABLE

Contacts and locations

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Locations

Cedars-Sinai Medical Center

Los Angeles, California, 90048, United States

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