Brain mapping breakthrough could revolutionize epilepsy surgery
NCT ID NCT04649008
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study combines advanced MRI scans with intracranial EEG recordings to map brain networks in people with drug-resistant epilepsy. Researchers aim to develop noninvasive imaging biomarkers that predict where seizures start and how they spread. The goal is to improve surgical outcomes and pave the way for more personalized, less invasive treatments. The study is recruiting 290 participants at the University of Pennsylvania.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better, less invasive ways to pinpoint seizure origins and improve epilepsy surgery success.
- What could go wrong
- This is an early-phase observational study, so it may not directly lead to new treatments. Results may not apply to all epilepsy patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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