EPILEPSY, TEMPORAL LOBE

This early-stage trial tests a single injection of special nerve cells (NRTX-1001) into both sides of the brain for people with severe epilepsy that doesn't respond to medication. The goal is to see if it's safe and can reduce seizure frequency. Ten adults aged 18-75 with confirm…

This study tests brain surgery as a treatment for people with epilepsy that medication cannot control. It includes children and adults aged 8 and older who have partial seizures starting in one area of the brain. The goal is to remove or treat the seizure-causing brain area to st…

This study tests a device called NaviFUS™ that uses low-intensity focused ultrasound to calm overactive brain areas in people with epilepsy that doesn't respond to medication. About 16 adults will be randomly assigned to receive the ultrasound treatment or continue standard care.…

This study looks at how the brain remembers places and scenes in people with epilepsy. Researchers will use a virtual tour task to map memory circuits in the brain. The goal is to help doctors avoid damaging memory during epilepsy surgery. About 620 adults with epilepsy and healt…

This study aims to improve how doctors plan epilepsy surgery by using advanced MRI scans to map brain connections. Researchers will compare these scans with electrical recordings from inside the brain in 290 people with drug-resistant epilepsy. The goal is to develop noninvasive …

This study tests a new MRI technique using ferumoxytol, an iron-based dye, to get clearer images of blood vessels in the hippocampus—a brain area key to memory and seizures. Researchers will compare images from 50 adults (healthy volunteers and epilepsy patients) to see if this m…

This study aims to learn more about epilepsy, especially in people whose seizures don't improve with medication. Researchers will screen up to 1,000 adults and children aged 8 and older using tests like EEGs, MRIs, and memory assessments. The goal is to better understand these se…