Could donated fat ease arthritis in your hands?
NCT ID NCT05747469
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial is testing whether injecting donated fat tissue into the small joints of the hand can reduce pain and improve movement in people with hand osteoarthritis. About 34 adults with joint pain and X-ray evidence of arthritis will receive the injection under local anesthesia. Researchers will measure changes in strength, range of motion, pain, and disability over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- donated fat tissue (allograft adipose matrix)
- What this could lead to
- If it works, this could offer a simple, off-the-shelf injection to reduce hand pain and disability without needing surgery or the patient's own fat.
- What could go wrong
- This is a very early, small trial with only 34 people, so results may not apply widely. The treatment is still experimental and safety and effectiveness are not yet proven.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cedars-Sinai Medical Center
Los Angeles, California, 90048, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.