Cedars-sinai Medical Center

This study tests whether early heart checkups and medication changes can lower heart risks in prostate cancer patients receiving hormone therapy. About 80 men with advanced prostate cancer and heart risk factors will either get standard care or a special heart consultation. The g…

This study tests whether giving people the choice between two weight management strategies—avoiding tempting foods or resisting cravings—helps them stick to their plan better than being assigned a strategy. Researchers will enroll 60 adults with overweight or obesity and track ho…

This study tests whether a special low-calorie diet that mimics fasting, done for 5 days each month over 6 months, is safe and can improve blood flow to the brain. It includes 40 adults aged 45-65 who carry a gene (APOE4) that raises their risk for Alzheimer's. Participants are r…

This study compares two standard treatments for severe narrowing of the heart's aortic valve in people born with a bicuspid (two-flap) valve. One treatment is a minimally invasive procedure (TAVR), the other is open-heart surgery (SAVR). The goal is to see which approach is safer…

This study tests whether mirabegron, a drug currently used for overactive bladder, can reduce dangerous heart rhythms in people with heart disease. Twenty adults with an implanted defibrillator and frequent ventricular tachycardia will take the drug for two months. The main goal …

This study compares a new, adjustable temperature cooler (RYOBI) to a standard FDA-approved device for storing donor hearts during transport to the hospital. Researchers want to see if the new cooler works just as well, while being cheaper and creating less waste. The study will …

This study tests whether taking S-adenosylmethionine (SAMe), a common supplement, can prevent liver injury caused by the chemotherapy drug oxaliplatin in people with colorectal cancer that has spread to the liver. About 30 participants will take SAMe pills daily for 3-6 months al…

This study tests whether a natural supplement called SAMe can help prevent liver cancer in people with advanced fatty liver disease (MASLD) and cirrhosis. About 94 adults will receive either SAMe or a placebo daily for 12 months. Researchers will measure changes in a blood test t…

This study tests a bilingual online peer-support program for Korean-speaking breast cancer survivors and patients. The goal is to see if the program is easy to use and helps improve quality of life, reduce anxiety and depression, and increase social support. Participants will be …

This study tests whether using a virtual reality (VR) headset at home can help reduce chronic pain in people with pancreatitis. Twenty adults with long-term abdominal pain will use a special VR program designed to focus on the gut, along with a Fitbit to track activity. The goal …

This study tests whether mirabegron, a drug currently used for overactive bladder, can reduce symptoms of Postural Orthostatic Tachycardia Syndrome (POTS). POTS causes a rapid heart rate and other symptoms when standing up. The trial will compare mirabegron to a placebo in 36 adu…

This study tests a single, 2-hour online class called Empowered Relief for 100 adults with advanced osteoarthritis who cannot have joint replacement surgery. The class teaches simple pain management skills based on cognitive behavioral therapy and mindfulness. Researchers will me…

This study tests if spraying a numbing medicine (bupivacaine with epinephrine) over the diaphragm can reduce shoulder pain after laparoscopic gynecologic surgery. About 100 women will receive either the numbing spray or a saltwater spray during surgery. Researchers will compare p…

This study tests whether a digital inhaler can help people with chronic lung disease (like COPD) avoid hospital visits and control symptoms better. Researchers will enroll 20 adults to see if the approach is practical and easy to stick with for 6 months. The goal is to gather inf…

This study looks at how the brain uses memories of past experiences to guide behavior in new situations. Researchers will monitor brain activity in 114 adults with epilepsy who are already undergoing brain monitoring. Participants will perform simple computer tasks to help scient…