SAMe supplement may shield liver from chemo harm
NCT ID NCT06258525
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether taking S-adenosylmethionine (SAMe), a natural supplement, can prevent liver injury caused by the chemotherapy drug oxaliplatin. About 30 adults with colorectal cancer that has spread to the liver will take SAMe pills daily for 3-6 months alongside their chemo, then have liver surgery. Researchers will check liver tissue for damage and compare it to past patients who did not take SAMe.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cedars-Sinai Medical Center Beverly Hills
Los Angeles, California, 90211, United States
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Cedars-Sinai Medical Center at SOCC
Los Angeles, California, 90048, United States
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