Could a stem cell transplant reset the immune system for young Crohn's patients?
NCT ID NCT04224558
First seen Feb 28, 2026 · Last updated May 16, 2026 · Updated 13 times
Summary
This study tests whether a stem cell transplant using the patient's own cells can 'reset' the immune system in teens and young adults (ages 13-28) with severe Crohn's disease that hasn't responded to other treatments. The approach removes overactive immune cells and replaces them with the patient's own blood stem cells. The goal is to reduce inflammation and heal the gut, but patients may still need ongoing medication.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Cedars-Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
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