Heart clot showdown: new blood thinner vs. old standard in major trial

NCT ID NCT05825573

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a newer type of blood thinner (DOA) works better than the standard one (VKA) for dissolving dangerous blood clots inside the heart. About 340 adults with such clots will be randomly assigned to one of the two treatments. The goal is to see which drug reduces the risk of death, stroke, or other serious events while causing fewer bleeding problems.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome Embolism heart failure ST-elevation myocardial infarction stroke disorder thrombotic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AP-HM CHU La Timone

    Marseille, France

  • AP-HP CHU Bichat

    Paris, France

  • AP-HP CHU Lariboisière

    Paris, France

  • AP-HP Hopital Ambroise Paré

    Paris, France

  • Ap-Hp Hegp

    Paris, France

  • CH Bastia

    Bastia, France

  • CH Chartres

    Chartres, France

  • CH Compiègne Noyon

    Compiègne, France

  • CH Francois Mitterand

    Pau, France

  • CHR Metz-Thionville

    Metz, France

  • CHU Angers

    Angers, France

  • CHU Arnaud de Villeneuve

    Montpellier, France

  • CHU Brest

    Brest, France

  • CHU Gabriel Montpied

    Clermont-Ferrand, France

  • CHU La réunion NORD

    Saint-Denis, Reunion

  • CHU Lille

    Lille, France

  • CHU Limoges

    Limoges, France

  • CHU Nantes

    Nantes, France

  • CHU Nice

    Nice, France

  • CHU Pitié-Salpêtrière

    Paris, France

  • CHU Poitiers

    Potiers, France

  • CHU Rennes

    Rennes, France

  • CHU Strasbourg

    Strasbourg, France

  • CHU Toulouse

    Toulouse, France

  • CHU de Nimes

    Nîmes, France

  • Centre Cardiologique du Nord

    Saint-Denis, France

  • Centre Hopistalier de Valence

    Valence, 26000, France

  • Ch Auxerre

    Auxerre, 89000, France

  • Ch Avignon

    Avignon, France

  • Ch Bretagne Atlantique

    Vannes, 56000, France

  • Clinique du Millenaire

    Montpellier, France

  • Groupe Hospitalier Mutualiste

    Grenoble, France

  • Hôpital Cardiologique du Haut Lévêque

    Bordeaux, France

  • Hôpital Cardiovasculaire Louis Pradel

    Lyon, France

  • Hôpital Privé Dijon Bourgogne

    Dijon, France