Centre Hospitalier Universitaire De Nīmes

This study is testing if having a dedicated case manager helps young people (aged 16-30) who have just experienced their first psychotic episode. The case manager provides personalized support, education, and helps with school, work, and family life. The main goal is to see if th…

This study is testing whether a special care team focused on older adults can improve recovery after colon cancer surgery. It will compare the new team approach to standard hospital care for 90 patients aged 70 and over. The main goal is to see if this approach helps patients reg…

This study aims to find the best technique for robotic-assisted total knee replacement. It will compare keeping a key stabilizing ligament (the PCL) versus removing it during surgery. Researchers want to see if keeping the ligament helps patients feel less aware of their artifici…

This study is observing how well a new surgical device, the Anchorsure System, works for treating pelvic organ prolapse in women. It will follow 120 women for three years after their surgery to see if the device successfully supports the pelvic organs and to check for any side ef…

This study is testing if a small, planned procedure to block a specific artery three weeks before rectal cancer surgery can make the main operation safer. The goal is to see if this 'pre-conditioning' helps the bowel develop better blood flow, which could reduce the risk of serio…

This study is testing whether a shorter, 12-week therapy program is practical and acceptable for people dealing with both addiction and trauma (PTSD). The program, called ECCCLORE, teaches skills to manage emotions, tolerate distress, and improve relationships. Researchers will e…

This study aims to find the best way to prevent acid reflux after a common throat surgery for achalasia. It will compare taking a daily acid-reducing pill for a full year versus only taking the pill when symptoms appear. Researchers want to see which approach better protects the …

This study is testing a new 10-week therapy program called SINTYA for young adults (16-25 years old) with severe borderline personality disorder. The program includes weekly group and individual sessions designed to help manage impulsive behaviors, emotional difficulties, and red…

This study is testing whether a modified surgical technique that removes more surrounding tissue (mesentery) during Crohn's disease surgery is as safe as the standard approach. Researchers want to see if this method reduces the high rate of disease returning after surgery. The tr…

This study is testing a new support program to help cancer patients, especially older or frail ones, safely transition from the hospital back home. It involves a nurse consultation and a system where patients report their symptoms and well-being using a smartphone or tablet after…

This study is testing whether using a simple, quick finger-prick test for inflammation (CRP) in a doctor's office can help manage children with fever. It aims to see if having this immediate result helps doctors decide if a child needs to be sent to an emergency room or a lab for…

This study is testing a new, simpler ultrasound measurement to see if it can quickly tell whether a patient in shock will benefit from receiving IV fluids. Doctors will use a special ultrasound scan on the heart before and after giving fluids to 187 emergency room patients. The g…

This study aims to find a better way to diagnose adenomyosis, a painful condition where uterine tissue grows into the muscle wall. Researchers will measure levels of a protein called L-PGDS in blood, urine, and tissue samples from 60 women to see if it can serve as a reliable mar…

This study is testing a new, faster diagnostic tool called MinION for identifying the bacteria and fungi in serious bone infections of the foot in people with diabetes. It will compare the results from this new tool to the standard, slower lab culture methods. The goal is to see …

This study is testing if a music therapy app on a tablet can reduce anxiety as effectively as a calming gas (EMONO) for patients getting painful, scan-guided injections for low back pain. Researchers want to see if this simple, non-invasive method is a good alternative to the gas…

This study is testing if adding music therapy to a home walking program helps people with leg artery disease walk farther with less pain. It will involve 54 adults who experience leg pain when walking. Participants will do a 3-month walking program, with some using a special musi…

This study is testing a new urine collection device called PEASY on 20 hospitalized men. The goal is to see if it causes less pain, irritation, and discomfort than the penile sheaths currently used. Researchers will measure how easy it is for caregivers to use and how well it pre…

This study aims to understand the basic cell biology behind serious pregnancy complications like pre-eclampsia and poor fetal growth. Researchers will observe and measure specific cell processes in 50 pregnant women who develop these conditions. The goal is to gather knowledge th…

This study aims to better understand how sitting posture affects the spine and pelvis in children with cerebral palsy who have limited walking ability. Researchers will take special X-rays of 100 children aged 4-17 while they are sitting to measure various spinal angles. The goal…

This study aims to understand how the gut bacteria of children and teenagers with a type of arthritis change while they are on different standard treatments. Researchers will collect stool samples from 25 young patients to see if the makeup of their gut bacteria is linked to how …

This study aims to understand if working unusual hours (like night shifts) or having idle time at work might increase the risk of developing problematic gambling behaviors. Researchers will interview 25 adults who currently gamble or have gambled in the past and who are employed.…

This study aims to understand how morning grogginess (sleep inertia) affects people with depression. Researchers will compare attention and alertness tests in three groups: depressed people with morning grogginess, depressed people without it, and healthy controls. The study uses…

This study aims to understand how long-term, low-dose antibiotics affect the diversity of gut bacteria in young children (aged 1-3 years) with a specific kidney condition. Researchers will compare stool samples from three groups: children taking the antibiotics, children with the…

This study aims to understand how blood transfusions affect heart function in elderly patients with anemia who come to the emergency room. Researchers will use heart ultrasound scans (echocardiograms) taken before, immediately after, and 15 minutes after a transfusion to measure …

This study aims to create and test a French version of a questionnaire that measures how well patients with rheumatoid arthritis follow their prescribed medication plans. Researchers will enroll 150 adults who have been taking methotrexate for their arthritis. The main goal is to…

This study aims to create a computer model using MRI scans to predict how well women with advanced cervical cancer will respond to standard chemotherapy and radiation treatment. Researchers will analyze past MRI data and treatment outcomes from about 120 patients to build this pr…

This study aims to identify what factors predict whether a person with chronic low back pain will benefit from a comprehensive rehabilitation program. Researchers will observe 333 patients undergoing standard non-drug treatments like physical therapy and counseling. The goal is t…

This study aims to understand how the brain creates auditory hallucinations (hearing voices) in people with schizophrenia. Researchers will use MRI brain scans to compare brain activity and connections in 40 participants—some who experience these voices and some who do not. The g…

This study is testing a new laboratory method called SPHERTEST to see if it can predict whether a patient's advanced bladder cancer will respond to immunotherapy drugs. Researchers will grow tiny 3D tumor models using cells from 32 patients and see how they react to immunotherapy…

This study aims to understand if changes in gut bacteria and a 'leaky gut' might be involved in causing type 1 narcolepsy, a serious sleep disorder. Researchers will compare 120 people with narcolepsy to healthy volunteers by analyzing their blood, stool, and spinal fluid. The go…