Personalized support after first psychosis: a 3-Year test

NCT ID NCT05116514

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether regular, personalized follow-up by a trained case manager can reduce the chance of another psychotic episode over three years in people aged 16 to 30 who have just had their first episode. 256 participants will be randomly assigned to either standard care or case management. The goal is to see if this approach can be rolled out widely to improve recovery and prevent relapse.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

case management (regular personalized follow-up by a trained case manager)

What this could lead to

If it works, this could provide a scalable way to improve long-term outcomes for young people after a first psychotic episode, reducing relapse and hospitalizations.

What could go wrong

This is an open-label study, so both patients and staff know who gets the intervention, which can bias results. It is also relatively small (256 people) and focuses on a specific age group, so findings may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

psychotic disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH Saint Marie Clermont-Ferrand

    NOT_YET_RECRUITING

    Clermont-Ferrand, France

    Contact Email: •••••@•••••

  • CHU Nice

    NOT_YET_RECRUITING

    Nice, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Montpellier

    RECRUITING

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • CHU de Nîmes

    RECRUITING

    Nîmes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

  • CHU de TOULOUSE

    NOT_YET_RECRUITING

    Toulouse, Choisir Une Région, 31, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier Léon-Jean Grégory

    RECRUITING

    Thuir, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••