Centre Hospitalier Universitaire De Nīmes

This study followed 75 women for 5-8 years after bladder prolapse surgery to compare two different repair methods. Researchers wanted to see which approach had better long-term results with fewer complications and less recurrence. The study specifically looked at whether using a …

This study tested a new approach to managing fluids in intensive care patients with septic shock. Researchers wanted to see if strictly limiting fluids given for routine maintenance and medication delivery, while still giving emergency resuscitation fluids, could improve a patien…

This study tested whether adding vitamin D supplements to standard diet and exercise advice improves blood vessel function in obese teenagers. Researchers compared 49 adolescents over three months to see if the vitamin D group showed better vascular health. The goal was to see if…

This study aimed to find out which type of exercise is better for helping the heart recover after a heart attack. Researchers enrolled 100 adults who had a recent heart attack and randomly assigned them to one of two 8-week exercise programs: steady, continuous training or high-i…

This study compared two types of dialysis (hemodiafiltration and hemofiltration) for patients with sudden kidney failure in intensive care. Researchers tested which method was better at removing urea (a waste product) from the blood over 12 hours and which kept the dialysis filte…

This study compared two types of minimally invasive surgery for pelvic organ prolapse, a condition where pelvic organs slip out of place. It involved 365 women and aimed to see if using a robot to assist the surgeon resulted in fewer complications within 30 days than standard lap…

This study tested a surgical mesh implant called Uphold LITE to treat pelvic organ prolapse, a condition where pelvic organs drop from their normal position. It involved 121 women who had the surgery and were followed for one year to see if the mesh corrected the anatomy, relieve…

This study aimed to find the safest speed for removing excess fluid from ICU patients whose kidneys have stopped working. Researchers tested three different removal rates on 39 critically ill patients to see which one caused the fewest dangerous drops in blood pressure while stil…

This study looked at whether using the medication dienogest during egg freezing works as well as standard protocols for women with endometriosis. Dienogest is a common treatment that helps control endometriosis pain and lesions. The research compared how many healthy eggs were co…

This study tested whether adding a low-dose immune drug called Interleukin-2 to standard ALS medication (riluzole) is safe and affects the immune system. It involved 36 adults with ALS who received either the drug or a placebo in three short courses over 12 weeks. The main goal w…

This study tested whether training surgical teams to use advanced digital monitors during anesthesia for major surgeries improves patient safety. Over 1,000 patients undergoing intermediate- or high-risk non-cardiac surgery were included. Researchers compared outcomes before and …

This study tested whether using a simple, daily bedside ultrasound scan to check a patient's fluid status could help doctors adjust heart failure medication more precisely. Researchers enrolled 250 adults hospitalized for acute heart failure to see if this approach led to fewer p…

This study looked at a new robotic surgery technique for early-stage throat (laryngeal) cancer. It followed 54 patients to see if the robot-assisted surgery could successfully remove all the cancerous tissue. The main goal was to check if the edges of the removed tumor were clean…

This study tested whether adding a clinical pharmacist to hospital care teams improves patient safety and reduces costs. It involved 500 patients admitted to infectious disease or internal medicine wards. The goal was to see if the pharmacist could help prevent medication errors …

This small, completed study tested a new idea for patients needing surgery for rectal or sigmoid colon cancer. Doctors wanted to see if temporarily blocking a specific artery (the inferior mesenteric artery) 3-4 weeks *before* the main surgery would help the body create new blood…

This study tested whether an 8-week personalized exercise program could improve heart and blood vessel function in men with type 2 diabetes or obesity. Researchers compared these men to healthy volunteers to understand how these conditions affect the body during rest and exercise…

This study aimed to find the best way to time the transfer of a frozen embryo during IVF. Researchers compared letting a woman's body ovulate naturally versus using a hormone injection (HCG) to trigger ovulation. They measured which method led to a higher pregnancy rate in women …

This small, completed study tested whether medications used to treat HIV (reverse transcriptase inhibitors) could help control psoriasis. Researchers gave these drugs to 8 people with long-term plaque psoriasis to see if they could reduce skin inflammation and improve lesions. Th…

This study tested whether a daily supplement containing spirulina (a type of algae) and silicon could improve the health and function of arteries in older adults. Researchers enrolled 120 healthy elderly participants to take either the supplement or a placebo for six months. They…

This study tested whether extending the time gambling companies stop sending marketing messages after a person self-excludes helps them gamble less. Over 2,500 adults with gambling problems were randomly assigned to either get 9 months of blocked ads or the standard procedure. Re…

This study tested whether having a pharmacist check in with people who have chronic obstructive pulmonary disease (COPD) after they leave the hospital could help them stay healthier at home. Researchers followed 174 adults with moderate to severe COPD for a year to see if these c…

This study tested two different ways to prevent blood clotting during dialysis for patients in intensive care who are at high risk of bleeding. It compared a method that thins blood only in the dialysis machine (regional citrate) to a low-dose method that thins blood throughout t…

This study tested whether personalized advice from a dietitian helps people with multiple sclerosis (MS) get enough calcium from their diet better than just receiving a standard information sheet. It involved 182 adults with MS who could walk and had never had specific calcium ad…

This study tested whether a low-dose immune drug (IL-2) could slow the progression of ALS by boosting helpful immune cells that may calm inflammation in the nervous system. It involved 304 newly diagnosed ALS patients who received either the drug or a placebo for 18 months. The m…

This study tested whether giving higher doses of two common antibiotics (amikacin and gentamicin) would reach effective levels in the blood of critically ill patients with severe sepsis. Researchers enrolled 63 ICU patients to see if these increased doses achieved target concentr…

This study tested whether a computer program could help doctors personalize the dose of a powerful antibiotic (amikacin) for patients with septic shock, a life-threatening condition. Researchers wanted to see if using the software helped more patients reach the ideal drug level i…

This study tested whether a psychological technique called 'evaluative conditioning' could help people recovering from a heart attack exercise more intensely during their cardiac rehabilitation. Researchers worked with 24 patients to see if linking positive feelings with exercise…

This study tested whether asking patients to report their symptoms via a smartphone or computer before a chemotherapy appointment could help doctors decide whether to prepare their treatment drugs. The goal was to see if this patient feedback was as useful as a doctor's exam in m…

This small pilot study tested a procedure called prostatic arterial embolization (PAE) in men with early, low-risk prostate cancer who were on active surveillance. The goal was to see if blocking the blood supply to the cancerous part of the prostate could control the tumor local…

This study tested if a special support program could help people stay physically active after a heart attack. It involved 84 patients who had completed the main part of their cardiac rehab. The program paired patients with a 'patient partner'—a fellow survivor—and a healthcare pr…

This study tested a new automated software tool on an ultrasound machine to see if it could measure heart pumping strength as accurately as a doctor doing it manually. It involved 70 critically ill patients in the ICU whose hearts were struggling to pump enough blood. The goal wa…

This study tested if a simple, non-invasive ultrasound scan of the diaphragm (the main breathing muscle) could help doctors in the emergency room. Researchers scanned 104 patients who arrived with severe breathing trouble but were still breathing on their own. The goal was to see…

This study tested a French version of a tool called the Confusion Assessment Method (CAM) to see how well it can diagnose confusion (delirium) in older adults. Researchers compared the tool's results against a psychiatrist's expert diagnosis in 102 hospitalized elderly patients. …

This study tested which of two laboratory methods works better for finding bacteria in bone and joint infections during surgery. Researchers compared a grinding technique against standard methods using samples from 122 patients. The goal was to determine which method is more accu…

This study looked back at 300 patients who had their thyroid gland removed. Researchers wanted to see if measuring a hormone (PTH) right after surgery could reliably predict which patients would NOT develop low calcium levels (hypoparathyroidism). The goal was to find a test resu…

This study tested if measuring a protein called S100B in the blood could help doctors in the emergency room. The goal was to see if the test could quickly tell the difference between common headaches and headaches caused by a more serious underlying medical problem. Researchers c…

This study tested a new needle-steering device designed to help doctors place central intravenous (IV) lines more accurately. The trial involved 124 intensive care unit (ICU) patients who needed this type of line. Researchers compared the new device, which uses magnets for better…

This study tested whether a simple, non-invasive ultrasound scan could help doctors diagnose a rare genetic condition called CANVAS. CANVAS causes problems with balance, coordination, and sensation due to nerve damage. Researchers compared ultrasound images of nerves in 35 people…

This study tested whether using ultrasound to guide a common nerve test could make it less painful and more accurate. Researchers compared the standard nerve test method to one where ultrasound helped find the best spots to stimulate nerves. They measured if this reduced the elec…

This study aimed to see if a blood test taken before hip or knee replacement surgery could predict which patients are at high risk for developing dangerous blood clots in their legs or lungs after the operation. Researchers tested 146 adult patients undergoing these surgeries. Th…

This study tested a new method for measuring systolic blood pressure in people with severe kidney failure. Researchers compared a technique that analyzes the pulse wave from the foot to the heart against the standard method of listening with a stethoscope. The goal was to see if …

This study tested whether using an ultrasound machine helps medical staff draw blood from the wrist artery more successfully on the first try. It involved 74 patients who needed this type of blood test for medical reasons. Researchers compared the standard method to using ultraso…

This study aimed to see if measuring a protein called NGAL in the blood could help doctors predict which patients with severe muscle breakdown (rhabdomyolysis) would develop sudden kidney failure. Researchers followed 197 patients admitted to emergency rooms with this condition. …

This study tested if using an ultrasound machine helps nurses draw blood from difficult-to-find arteries in the wrist. It compared the standard method of feeling for the artery with using ultrasound to see it on a screen. The goal was to see which method was more successful on th…

This study looked at whether a special type of PET scan (FDOPA-PET) can better tell the difference between brain tumors and non-cancerous brain lesions. Researchers analyzed past scan data from 74 patients who had suspicious brain findings on an MRI. The goal was to find the best…

This study tested whether using newer, faster lab machines could help doctors choose the best antibiotic treatment more quickly for ICU patients with serious bloodstream infections. Researchers compared patient care before and after introducing these rapid diagnostic tools in one…

This study tested whether using two tools together helps doctors find more pre-cancerous growths (adenomas) during a colonoscopy. The tools are an artificial intelligence (AI) system that highlights suspicious areas and a small cap that helps flatten the colon wall for a better v…

This study aimed to find the best way to detect and measure Candida fungal infections early in patients staying in intensive care units (ICUs). Researchers tested four different lab methods on 422 ICU patients to see which ones could best identify who had an infection. The goal w…

This study tested a new automatic tool on a pocket-sized ultrasound device to see if it could reliably measure how well the heart pumps blood. Researchers compared this tool's measurements against the standard visual method used by doctors in emergency rooms. The goal was to see …

This study compared two short screening tests to see which one better identifies thinking and memory problems in people being treated for alcohol use disorder. Researchers gave both tests to 90 hospitalized patients and compared the results to more detailed brain function tests. …

This study tested whether two types of brain scans (PET and CT perfusion) could predict if patients with recurrent glioblastoma would respond to bevacizumab treatment. Researchers enrolled 14 patients whose brain cancer had returned after standard treatments. The goal was to see …

This study tested a new type of medical scanner designed to use much less radiation than standard X-rays. Researchers compared how well this 'Ultra Low-Dose' scanner and standard X-rays could find broken bones in the back, pelvis, arms, and legs of 554 emergency room patients. Th…

This study tested whether having hospital pharmacists check patients' vaccination status and help organize follow-up shots could increase vaccination rates against serious bacterial infections. It involved 646 adult patients at high risk for pneumonia and meningitis who were hosp…

This study tested if placing a supportive mesh during the initial surgery to create a colostomy (stoma) could prevent a common and painful complication called a parastomal hernia. 200 patients getting their first colostomy were randomly assigned to have the surgery with or withou…

This study tested whether a pharmacist could help more at-risk patients get vaccinated against serious pneumococcal infections (like pneumonia and meningitis) when leaving the hospital. Researchers enrolled 167 adult patients who were eligible for the vaccine but hadn't received …

This study tested whether cranberry capsules could prevent E. coli urinary tract infections from catheters placed during pelvic surgery. Researchers enrolled 270 patients to see if the cranberry treatment reduced bacteria sticking to catheters. The goal was to lower the risk of h…

This study tested whether having a pharmacist work directly with the anesthesiologist before surgery could help prevent medication errors. It involved 378 patients with chronic health conditions who were having scheduled surgeries like urology or orthopedic procedures. The goal w…

This study tested a special wheelchair designed to absorb the force of involuntary movements. Four participants with conditions causing excessive movements tried the chair in both a flexible 'dynamic' mode and a standard 'static' mode. The goal was to see which setting was more c…

This study tested whether ketamine, given as an infusion, could provide rapid relief from suicidal thoughts in people hospitalized for suicide risk. In this Phase 3 trial, 156 participants were randomly assigned to receive either ketamine or a placebo to see which was more effect…

This study tested a special device that uses gentle electrical pulses to stimulate paralyzed hand muscles in people who have had a stroke. The goal was to see if this 'neuroprosthesis' could help participants perform basic tasks like picking up a glass or a spoon, which they coul…

This study looked back at the results of a surgical procedure to tighten vaginal muscles in women experiencing a feeling of excessive looseness, often after childbirth. Researchers reviewed the cases of 55 women who had the surgery to see if it improved their sexual health and re…

This study aimed to see if using hypnosis was as good as nitrous oxide gas (MEOPA) for controlling pain in children getting stitches in the emergency room. Researchers compared the two methods in 60 children with wounds needing stitches. They measured pain levels, how long the pr…

This study tested whether a numbing medicine called ropivacaine, given during surgery, could better control pain in the first 24 hours after having all four wisdom teeth removed. It compared the medicine against a placebo (a shot with no active drug) in 100 patients. Researchers …

This study tested whether giving the medication remifentanil during emergency breathing tube placement could reduce dangerous spikes in heart rate. It involved 75 fragile patients who needed this urgent procedure. Researchers compared two different doses to see which was safer an…

This study created and tested a new education program for men with advanced prostate cancer who are on specific hormone therapies. The goal was to see if teaching patients more about their disease and treatment could help them take their medications correctly and feel better over…

This small study tested whether adding augmented reality mirror therapy to standard physical therapy helps people with complex regional pain syndrome (CRPS) in their arm. CRPS causes severe, long-lasting pain, swelling, and movement problems. Researchers had patients use special …

This study tested whether adding a drug called nefopam to standard morphine pain relief could help manage pain better after major colon surgery. It involved 80 adults undergoing planned surgery for colon cancer or diverticulosis. The main goal was to see if this combination could…

This study tested whether breathing a mixture of nitrous oxide and oxygen during physical therapy helps people with frozen shoulder. It compared patients who received the gas during therapy to those who did not. The goal was to see if the gas reduced pain and allowed for better s…

This study looked at whether a standard rehabilitation program helps people with long-term low back pain become more physically active and sit less. Researchers followed 89 patients to see if their activity levels and motivations changed during and after the program. The goal was…

This study compared two strong pain medications given through an IV after hip replacement surgery. It aimed to see if oxycodone caused 50% fewer side effects—like nausea, vomiting, and itching—than the commonly used morphine. The trial involved 246 adults recovering from hip surg…

This study compared two types of anti-bedsore mattresses to see which one does a better job of spreading out pressure on a patient's skin. Researchers measured how much time the pressure stayed at safe levels on the lower back and buttocks of 31 bedridden patients. The goal was t…

This study tested different combinations of common pain medications to find which one best improves recovery after outpatient shoulder surgery. Researchers compared adding either tramadol, nefopam, or another opioid to a standard two-drug pain regimen. They measured recovery usin…

This study tested a special 'remission' consultation for breast cancer survivors who recently finished their main treatments. Researchers followed 50 patients for a year to see if this consultation improved their quality of life, body image, and ability to return to work. The goa…

This study tested whether a simple, targeted nerve block could reduce pain and the need for strong painkillers like morphine after lower back surgery. Researchers compared the nerve block using a local anesthetic against a placebo in 50 patients. The goal was to see if this appro…

This study tested whether leaving the tooth sockets open after removing all four wisdom teeth reduces pain compared to the standard practice of stitching them closed. It involved 100 patients who had their wisdom teeth removed under general anesthesia. Researchers measured pain, …

This small pilot study tested whether injecting a gel-like substance called hyaluronic acid into the vaginal lining could help menopausal women experiencing painful intercourse and vaginal dryness. Researchers measured changes in vaginal tissue thickness, comfort, and other facto…

This study tested whether stimulating nerves on one side or both sides works better for overactive bladder that doesn't respond to usual treatments. Researchers compared these two approaches in 55 patients over one month to see which provided better symptom relief. The goal was t…

This small pilot study tested a new medical device that uses gentle light therapy to treat vaginal atrophy in postmenopausal women. The device aims to reduce pain and improve vaginal health by stimulating tissue repair. Researchers primarily wanted to see if the treatment was saf…

This study compared two methods for removing breathing tubes when patients wake up from general anesthesia. Researchers wanted to see if using positive pressure (gentle air push) helps patients maintain better oxygen levels compared to the standard suction method. The study invol…

This study looked at two versions of a procedure called prostate artery embolization. It involved 50 elderly men who had long-term urinary catheters due to an enlarged prostate and couldn't have surgery. Researchers compared whether blocking arteries on one side or both sides of …

This study tested whether adding a longer-lasting numbing medicine (ropivacaine) to the standard numbing shot (lidocaine) improves recovery after outpatient hand, wrist, or elbow surgery. Researchers compared the two methods in 91 patients to see which led to less pain and a bett…

This study compared three different types of breathing tubes used during short surgeries to see which one causes less sore throat afterward. Researchers tested the devices on 546 adults having elective surgeries lasting less than two hours. They measured how often patients experi…

This study aimed to understand how cancer-related DNA in the blood changes before, during, and after surgery. Researchers followed 30 patients with breast, prostate, or colon cancer who were having surgery intended to cure their disease. The goal was to gather basic information t…

This study aimed to understand how a serious foot complication called Charcot foot is currently managed in people with diabetes. Researchers observed the diagnosis and treatment practices for over 1,100 patients across medical centers in France and Belgium. The goal was to gather…

This study compared two different ultrasound-guided techniques for placing a central venous catheter, a tube inserted into a large vein for medication or monitoring. Researchers randomly assigned 132 patients needing this procedure to have the catheter placed either near the coll…

This study aimed to understand how the COVID-19 pandemic affected the mental health of nursing home staff in France. Researchers surveyed 501 workers to measure rates of post-traumatic stress, depression, and burnout. The goal was to document the psychological impact of working t…

This study examined brain scans of 111 patients with cerebral amyloid angiopathy (CAA), a condition where protein builds up in brain blood vessels. Researchers analyzed MRI images to understand where and how bleeding occurs in the cerebellum (the lower back part of the brain). Th…

This study aimed to understand how a strong antibiotic, ceftobiprole, moves through the bodies of very sick pneumonia patients who need breathing machines. Researchers measured drug levels in the blood and lungs of 12 patients to figure out the best dose to fight the infection. T…

This study aimed to understand how often colostomy patients use bowel irrigation to manage their condition. Researchers surveyed over 1,100 French colostomy patients to compare quality of life between those who use irrigation and those who don't. The study also explored why some …

This study looked at whether having unusual vaginal bacteria during pregnancy makes vaginal tears more likely during childbirth. Researchers examined medical records of 1,100 women who gave birth in a French hospital. They compared bacteria test results from pregnancy with whethe…

This small pilot study aimed to understand how fear of pain affects walking in people with chronic low back pain. Researchers measured walking patterns and pain levels in 16 participants while they walked normally and while distracted. The goal was to see if distraction could red…

This study aimed to understand how two natural cell processes work together during pregnancy. Researchers measured these processes in 97 women with normal pregnancies and those at higher risk for complications. The goal was to gather basic knowledge that could help explain why so…

This study looked at whether a specific marker measured during a routine blood test (called NEU-SFL) could help predict which patients hospitalized with COVID-19 were more likely to die. Researchers analyzed data from over 2,200 patients hospitalized in 2021. The goal was to see …

This study aimed to understand how compression stockings of different strengths affect pressure and vein size in the legs. It involved 111 participants, including people with chronic venous insufficiency and healthy volunteers. Researchers measured vein pressure and size while pa…

This study aimed to see if a special laboratory test, called an antibiofilmogramme, could help predict whether a specific antibiotic would successfully treat a diabetic foot infection. Researchers observed 33 patients with infected foot wounds to see if the test results matched h…

This study observed how doctors in French hospitals treated patients with spleen injuries from accidents or trauma. Researchers tracked 93 patients to see which treatments were used, how long people stayed in the hospital, and what complications occurred. The goal was to understa…

This study aimed to understand if the community of bacteria in the gut (the microbiome) is different in people newly diagnosed with rheumatoid arthritis (RA) compared to people without RA. Researchers enrolled 55 participants, including RA patients and healthy volunteers, to coll…

This study looked at whether a mental practice technique could help medical students get better at inserting IV catheters. Researchers had 96 fifth-year medical students practice the procedure on a training mannequin. They tested if students who first imagined performing the step…

This study aimed to understand how chronic low back pain affects movement stability. Researchers compared 70 participants—some with long-term back pain and some healthy volunteers—by measuring their movement patterns during different exercises. The goal was to gather knowledge ab…

This study aimed to understand how often children correctly take their prescribed antibiotics after being discharged from the hospital. Researchers followed 75 children under 16 years old for one month after they went home with an antibiotic prescription. The goal was to measure …

This study aimed to understand the psychological impact of the COVID-19 pandemic on hospital staff, especially those working in Intensive Care Units (ICUs). Researchers surveyed 701 doctors, nurses, and other caregivers to measure rates of post-traumatic stress, anxiety, depressi…

This study aimed to understand the underlying causes of Henoch Schönlein Purpura (HSP), a disease causing skin rash and other symptoms in children. Researchers compared blood samples from 100 children—some with active HSP, some in remission, and some healthy—to see if specific im…

This study looked at how emergency room doctors make decisions about prescribing strong pain medication for sickle cell disease patients. Researchers presented 1,063 emergency physicians across Europe with a fictional patient case and asked what treatment they would choose. The g…

This study tested whether a new magnetic needle-pilot device helps doctors place central venous catheters more successfully than standard ultrasound guidance. Researchers compared the two techniques using a realistic mannequin torso, measuring how long it took and how many attemp…

This study aimed to understand how strokes caused by a clot inside the heart look different on brain MRI scans compared to strokes caused by a common heart rhythm problem called atrial fibrillation. Researchers analyzed detailed MRI scans from 122 stroke patients to compare the l…

This study looked at whether having a vaginal birth or a C-section affects a first-time mother's risk of developing urinary incontinence after delivering twins. Researchers followed over 3,000 women who gave birth to twins after 34 weeks of pregnancy. They compared symptoms like …

This study looked back at data from over 1.5 million intensive care unit (ICU) admissions across France between 2013 and 2019. Its goal was to understand how ICU care changed, including death rates, length of stay, and patient sickness levels. Researchers analyzed hospital record…

This study aimed to understand if people with a history of dangerous blood clots (venous thromboembolism) have specific, age-related mutations in their blood cells. Researchers tested DNA from 150 patients over 50 years old who had experienced clots. The goal was to gather knowle…

This study aimed to see if a simple finger-prick blood test for monitoring blood thinners in elderly nursing home residents would lead doctors to make the same treatment decisions as the standard, more invasive arm-stick test. Researchers observed 31 residents over six months. Th…

This study aimed to understand if the same bacteria found in the nose could cause foot infections in people with diabetes. Researchers compared the bacteria from the noses and foot ulcers of 278 diabetic patients to see if they matched. The goal was to learn more about how these …

This study aimed to understand motor conversion disorder, a condition where psychological stress causes physical symptoms like paralysis or weakness. Researchers used special brain scans (PET scans) on 20 patients at the start of their symptoms and again 3 months later. The goal …

This study observed how stroke patients walk to gather data that could improve electrical stimulation devices. These devices help lift the foot during walking when muscles are weak. Researchers measured the timing of foot movements in 20 stroke patients to help future devices wor…

This study tested how well a small, wearable sensor could measure walking movements in people who have had a stroke and have difficulty lifting their foot. Researchers compared the sensor's data to that from large, specialized lab equipment. The goal was to see if the sensor coul…

This study aimed to understand if certain substances in the blood differ between healthy pregnancies and those with serious complications. Researchers compared 137 women across three groups: those with pregnancy complications, healthy pregnant women, and healthy non-pregnant wome…

This study aimed to find out how many people held in a specific French detention center had HIV, hepatitis B, or hepatitis C. Researchers used rapid tests to screen 350 detainees, as many come from regions where these infections are common and may not know their status. The goal …

This study looked at whether special heart mapping techniques can predict how well a common treatment for atrial fibrillation (irregular heartbeat) will work. Researchers followed 175 patients who received radiofrequency ablation treatment, tracking them for 18 months to see if t…

This international study observed how doctors prescribe specific antibiotics called aminoglycosides to critically ill patients in intensive care units (ICUs). Researchers collected data from 964 patients across multiple countries to understand current dosing practices and identif…

This study aimed to better understand a rare type of stroke caused by tiny, hard pieces of calcium breaking loose and traveling to the brain. Researchers looked at the medical records and brain scans of 79 patients who had this condition. The goal was to describe the patients and…

This study aims to understand how COVID-19 mRNA vaccines affect certain immune cells called monocytes. Researchers want to see if vaccine particles in the bloodstream could trigger a chain reaction that might reduce the body's long-term immune memory. They enrolled 30 participant…

This study aimed to understand how a specific type of white blood cell behaves differently in healthy pregnancies compared to those with preeclampsia, a serious blood pressure condition. Researchers analyzed previously collected blood samples from 26 women to compare two differen…

This study aims to understand if a specific type of immune cell can cause insulin resistance, which is linked to high insulin levels and conditions like type 2 diabetes. Researchers will analyze blood samples from 30 people who were in a previous health study. The goal is to see …

This study aimed to understand how pain changes in the first week after surgery and see if those patterns can help predict who might develop long-term chronic pain. Researchers followed 392 patients who had various planned surgeries, tracking their daily pain levels. The goal was…

This study aimed to create a decision-making tool to help doctors identify which patients hospitalized with severe kidney injury are most likely to develop chronic kidney disease. Researchers followed 319 patients who needed dialysis for acute kidney injury to understand what fac…

This study aimed to understand if the timing of checking a patient's response to intravenous fluids matters in septic shock. Researchers gave 145 critically ill patients a standard fluid dose and measured their heart's response immediately after and 20 minutes later. The goal was…

This study aimed to understand why some COVID-19 patients develop severe breathing problems. Researchers measured detailed immune system activity in 120 hospitalized patients with respiratory distress. They compared these patients to healthy volunteers to identify specific immune…

This study compared two different spots in the neck and chest for placing a central venous catheter, a tube used to give medicine or fluids. Doctors used ultrasound to guide the tube into either the lower jugular vein or the subclavian vein in 210 adult patients. The goal was to …

This study aimed to find early warning signs in the blood for serious pregnancy complications like pre-eclampsia. Researchers measured specific proteins in 115 women across three groups: those with normal pregnancies, those with placental complications, and healthy non-pregnant v…

This study aimed to understand if nerve blocks used for hand or wrist surgery last a different amount of time in people with kidney failure or diabetes compared to healthy people. Researchers enrolled 120 patients having surgery to measure how long the numbing effect lasted. The …

This study aimed to understand why some hospitalized COVID-19 patients develop serious blood clotting problems, which is a major risk factor for death. Researchers tested the blood of 175 patients using a detailed clotting analysis when they were first admitted to the hospital. T…

This study aimed to discover if a simple blood test could detect early signs of cancer spread from intestinal polyps. Researchers compared blood samples from 120 people with polyps to those without, looking for specific cells and proteins. The goal is to find better ways to monit…

This study looked back at how France's healthcare system rapidly created more intensive care unit (ICU) beds and found staff during the COVID-19 crisis. Researchers analyzed data from nearly 10,000 patients across French hospitals to understand where the new beds came from and ho…

This study tested whether ultrasound measurements of diaphragm movement give consistent results when different doctors perform them on emergency room patients with severe breathing difficulties. Researchers enrolled 26 patients who were breathing on their own but struggling to br…

This study aimed to understand how doctors use newer therapies—like special lights, lasers, radio waves, and injections—to treat women's pelvic and perineal conditions when standard medical treatments don't work well enough. Researchers observed 173 women with conditions like chr…

This study aimed to understand what might cause some people with early brain changes (Radiologically Isolated Syndrome) to develop full multiple sclerosis (MS). Researchers checked blood samples from 110 people to look for signs of Epstein-Barr virus infection and measure vitamin…

This study aimed to validate a scoring system that uses early blood test results to predict which patients with septic shock are most likely to die within one month. Researchers enrolled 780 critically ill patients in intensive care units to test how well the score works. The goa…

This study aimed to understand how the community of bacteria in the vagina changes before and after gynecologic surgery. Researchers followed 60 menopausal women undergoing vaginal surgery, taking swabs to analyze their vaginal bacteria at multiple points. The goal was to see if …

This study looked at mental health conditions in women who experienced multiple pregnancy losses. Researchers compared three groups of women with similar pregnancy histories 10 years after their initial diagnosis. The goal was to understand whether certain blood clotting disorder…

This study tested whether using new guidelines for ordering imaging tests (like X-rays or CT scans) in the emergency department would lead to more accurate test results and reduce patient wait times. It involved over 8,500 patients. Researchers compared what happened before and a…

This study looked at 100 critically ill patients with circulatory shock to see if the amount of the drug norepinephrine they received was connected to their chances of survival. Researchers analyzed patient records to understand the relationship between drug dose, how long it was…

This study looked back at 156 critically ill patients to understand what factors help achieve proper antibiotic levels in the blood. Researchers analyzed patient characteristics and treatment monitoring data to identify why some patients reach target antibiotic concentrations whi…

This study used MRI brain scans to see if a condition called obstetric antiphospholipid syndrome causes changes in the brain's white matter over several years. Researchers compared scans from 40 women who had pregnancy complications due to this immune disorder against scans from …

This study looked back at 120 patients treated in French intensive care units for gunshot wounds between 2015 and 2021. Researchers wanted to understand what types of injuries these patients had, how many survived, and what factors might predict their chances of recovery. The goa…

This study aimed to understand how septic shock, a life-threatening response to infection, affects the gut. Researchers observed 60 adult patients in intensive care to see if damage to the gut lining allowed bacteria to leak into the bloodstream. They measured markers in the bloo…

This study aimed to better understand conversion disorder, a condition where psychological stress causes physical symptoms like paralysis or weakness. Researchers analyzed blood samples and brain scans from 20 adults experiencing their first episode within the past month. They lo…

This study compared the total 5-year healthcare costs and patient outcomes between two prostate cancer surgery methods: robotic-assisted surgery and traditional open surgery. Researchers followed 90 patients with localized prostate cancer to track expenses, recovery, side effects…

This study tested a new, more sensitive type of heart ultrasound scan in 50 patients with septic shock, a life-threatening condition. The goal was to see if this new scan could better track heart function and predict which patients are more likely to survive their ICU stay. It wa…

This study aimed to find out if not eating or drinking before surgery (preoperative fasting) causes a significant drop in a patient's blood volume. Researchers enrolled 100 patients scheduled for gynecological or abdominal surgery. They used heart ultrasound scans to measure bloo…

This study aimed to understand why the cancer drug sunitinib works differently in different people. Researchers followed 43 patients with metastatic kidney cancer who were starting the drug. They measured drug levels in the blood, tracked side effects and tumor response, and look…

This study looked back at medical records to see if a common heart condition called a patent foramen ovale (PFO), or 'hole in the heart,' is connected to specific types of small strokes in the cerebellum of young adults. Researchers compared 50 young patients who had an unexplain…

This study tested whether a newer CT scan reconstruction method (ASIR) could produce bone scan images of similar quality to the standard method (FBP) while using less radiation. Researchers compared image quality and radiation doses in 75 patients who were already scheduled for b…

This study aimed to see if training with a robot helps new surgeons learn a specific laparoscopic procedure faster than standard training. Thirty-four surgical interns were randomly assigned to train with or without robotic assistance. They were then timed performing the procedur…

This study aimed to understand if differences in genes related to how the body processes vitamin D are linked to ALS. Researchers compared the genetic makeup of 400 people with ALS to 400 people without the disease. The goal was to gather knowledge, not to test a treatment.

This study observed over 1,000 adults with severe COVID-19 who were treated in French intensive care units (ICUs). The goal was to document exactly how these critically ill patients were cared for and to identify which treatments and patient factors were linked to better or worse…

This study aimed to help doctors better distinguish between two similar-looking brain diseases by comparing patterns of white spots on MRI scans. Researchers analyzed brain scans from 315 patients who had either cerebral amyloid angiopathy (CAA) or hypertensive arteriopathy (HA).…

This study aimed to understand if critically ill patients in intensive care units receive the right amount of antibiotics in their blood to effectively fight infections. Researchers measured antibiotic levels in the blood of 98 patients and compared them to targets needed to kill…

This study looked back at medical records to understand how common blood thinners (DOACs) affect the care of older adults who break their hip. Researchers analyzed 610 patients over 65 to see if waiting for surgery to stop the blood thinner increased risks like death or complicat…

This study aimed to find out if drinking only when thirsty is a safe and effective hydration strategy for runners in an extreme, multi-day mountain race. Researchers followed 198 participants of the 2015 Ultra Trail du Mont-Blanc, comparing their blood sodium levels, weight chang…

This study aimed to compare two different blood test methods for finding melanoma cells that have spread in the body. Researchers tested 73 people, including patients with advanced melanoma and control patients without cancer. The goal was to see which test method was more effect…

This study aimed to find out if early changes in two blood markers (PGF and sFlt1) could predict pregnancy complications in women with antiphospholipid syndrome (APS). Researchers followed 513 women with APS who were starting a new pregnancy and receiving standard blood thinner i…

This study aimed to create and test a French version of a short questionnaire about back awareness for people with chronic low back pain. Researchers enrolled 150 people, including those with and without back pain, to see if the translated questionnaire is reliable and useful. Th…

This study tested whether a video call consultation with an anesthesiologist before scheduled surgery is as effective as a traditional in-person visit. Researchers compared the two methods for 172 patients to see if they collected the same quality of information about patient hea…

This study aimed to test and validate two French-language questionnaires designed to measure sexual function. It involved 298 women who had undergone surgery for pelvic organ prolapse or incontinence. The goal was to see if these new tools were reliable for understanding how thes…

This study aimed to gather basic knowledge about veins in the shoulder area. Researchers used ultrasound on 50 healthy volunteers to see how raising and rotating the arm changes the size and position of specific veins. The goal was to collect detailed measurements to help doctors…

This study aimed to understand how two antifungal drugs (caspofungin and micafungin) move through the bodies of critically ill patients. It involved 24 adults in intensive care with a severe abdominal infection (peritonitis) that led to septic shock. Researchers measured drug lev…

This study aimed to understand how prostate cancer affects men's quality of life three years after diagnosis, when they're expected to have returned to normal life. Researchers compared 900 men with prostate cancer to similar men without cancer, all living in the same region of F…

This study aimed to understand how two potential blood markers for dangerous blood clots (venous thromboembolism) change over time. Researchers measured these markers monthly for six months in 15 healthy volunteers and 15 people with a history of blood clots. The goal was to see …

This study aimed to understand if a person's social and economic situation is linked to how advanced their breast cancer is when first diagnosed. Researchers compared 684 women with early-stage cancer to those with later-stage cancer. They looked at factors like income, housing, …

This study aimed to understand how normal breathing changes the size of a large vein in the belly, called the inferior vena cava. Researchers used ultrasound scans on 52 healthy volunteers to measure the vein's movement and the diaphragm muscle's motion. The goal was to gather ba…

This study aimed to understand if being diagnosed with gestational diabetes earlier in pregnancy (before 24 weeks) leads to a higher risk of having diabetes or blood sugar problems after giving birth, compared to being diagnosed later. Researchers followed 500 pregnant women with…

This study aimed to create a baseline measurement of how healthy lungs move during normal and assisted breathing. Researchers used a special ultrasound technique on 30 healthy volunteers to measure lung stretch and movement. The goal is to help doctors better understand and inter…

This small, completed study aimed to understand how the brain reorganizes itself in the first two months after a stroke. Researchers used a special light-based brain scanner (fNIRS) on 10 recent stroke patients to measure brain activity while they performed hand and arm tasks. Th…

This completed study aimed to understand how the body's immune system activity relates to insulin resistance, a condition that can lead to type 2 diabetes and heart disease. Researchers measured many immune markers and health factors in 158 volunteers aged 55 to 69. The goal was …

This study aimed to understand if people with complex regional pain syndrome (CRPS) have difficulty with mental imagery—the ability to imagine movements without physically doing them. Researchers compared 129 people across three groups: those with CRPS, those with other musculosk…

This study aimed to see how accurately a common risk prediction tool, called the Wells score, works for patients already in the hospital. Researchers wanted to know if the score is reliable when patients are on preventive blood-thinning medication and if different doctors calcula…

This French study aimed to understand why some colon cancer cells are more aggressive. Researchers collected tumor samples from 60 patients to identify and study the specific cells responsible for spreading cancer and resisting chemotherapy. The goal was to learn more about these…

This study aimed to understand how often violence happens in a hospital emergency room and what factors might be linked to it. Researchers observed 90 different work shifts over a year, counting violent events and noting details like time of day and staff numbers. The goal was to…

This study looked at whether the position of a small neck bone (the hyoid bone) is related to narrowing of the carotid artery and stroke. Researchers analyzed CT scans from 206 patients who had surgery to clear a blocked carotid artery. The goal was to gather knowledge to better …

This study aimed to understand how two different blood filtering techniques work for patients with a rare nerve disorder called CIDP. It involved 8 patients who were already receiving regular blood filtering treatments. Researchers took blood samples to see how specific immune ce…

This study looked back at 15 stroke patients who had signs of a brain condition called cerebral amyloid angopathy (CAA) on their MRI scans. All patients received a standard clot-busting drug (IV thrombolysis). Researchers wanted to see if having CAA made these patients more likel…

This study observed how 200 adult patients with serious community-acquired abdominal infections were treated in emergency departments. Researchers tracked their care—including timing of surgery and antibiotics—to understand what factors lead to better or worse outcomes. The goal …

This study aimed to check if a new bone density scanner gives the same results as an older, trusted model. Researchers compared the two machines by scanning 50 people who were already scheduled for a bone density test. The goal was to see if the new scanner measures body fat, mus…

This study looked at whether measuring a specific protein (ADAMTS13) in the blood of pregnant women with Antiphospholipid Syndrome (APS) could help predict their risk of developing preeclampsia, a serious pregnancy complication. Researchers analyzed stored blood samples from 513 …

This study looked at whether women who experienced multiple early pregnancy losses or a late-term stillbirth have a different long-term risk of developing cancer. Researchers followed over 1,500 women for about 17 years, comparing those with specific blood clotting conditions to …

This study aimed to understand the hidden complexity in simple hand-tapping movements. Researchers measured how 60 healthy volunteers performed a finger-tapping test. The goal was to gather basic knowledge that might one day help assess or monitor certain neurological conditions.

This study aimed to understand how being on a ventilator in intensive care affects patients' memory and emotional health months later. Researchers followed 125 patients who were sedated and on breathing machines, checking in with them at 2 and 4 months after leaving the hospital.…

This study aimed to understand how people walk after a leg amputation. Researchers analyzed walking patterns from 130 patients during their rehabilitation to measure balance and symmetry. The goal was to gather detailed information that could help improve future prosthetic fittin…

This study aimed to understand if experiencing intimate partner violence increases a woman's risk of developing serious blood clots while taking birth control pills. Researchers compared 997 women on the pill—some who had clots and some who did not—matching them closely on factor…

This study aimed to understand why botulinum toxin injections, a common treatment for muscle stiffness (spasticity) after a stroke, can sometimes become less effective over time. Researchers measured tiny electrical signals, called 'jitter,' in the stiff arm muscles of 40 stroke …

This study aimed to understand how high-dose vitamin D affects the immune systems of healthy people. Researchers gave 56 participants either vitamin D or a placebo for three months and measured detailed changes in their immune cells. The goal was to gather basic knowledge about v…

This study tested a tablet device called SMART ANGEL that lets patients record and send health measurements from home after outpatient surgery. Researchers wanted to see if patients could easily use the device to track blood pressure, heart rate, and oxygen levels, and if the dat…

This study aimed to establish normal measurements for how much the pelvis can extend backward in healthy people. Researchers compared three different measurement methods—physical exam, photography, and a specialized low-dose X-ray system—in 120 healthy volunteers. The goal was to…

This study aimed to check how reliable and useful a specific questionnaire is for assessing balance and fall risk in frail elderly people. Researchers tested the questionnaire on 140 hospitalized patients aged 65 and older who could walk short distances. They compared the questio…

This study aimed to understand why only some patients with advanced bladder cancer benefit from immunotherapy. Researchers analyzed stool and blood samples from 40 patients to see if differences in their gut bacteria could predict treatment response. The goal was to gather knowle…

This study aimed to find better ways to predict if people with early brain scan abnormalities will develop multiple sclerosis (MS). Researchers tested new markers in blood and spinal fluid from 100 people who had these early scan findings. The goal was to see if these markers cou…

This study aimed to understand brain differences in people who attempted suicide, especially those who used violent methods. Researchers used MRI brain scans and decision-making games to compare 40 people across four groups: suicide attempters (violent and non-violent), people wi…

This small, completed study aimed to understand how different chairs affect the alignment of the lower back and pelvis. Researchers compared a standard straight chair to an 'ergonomic' chair in 20 people, some with chronic back pain and some without. The goal was to gather basic …

This study aimed to understand why many stroke survivors avoid using their weaker arm even when they physically can. Researchers tested 53 people, including stroke survivors and healthy volunteers, during simple reaching tasks to see how changing the required force or precision a…