Centre Hospitalier Universitaire De Nīmes

This study looked at 75 women who had surgery for bladder prolapse (a condition where the bladder bulges into the vagina). It compared two surgical methods: one using a mesh support (UGYTEX®) and one using stitches to tighten the tissue without mesh. The goal was to see which app…

This study tested a special mesh (Uphold LITE) to treat uterine prolapse, a condition where the uterus drops into the vagina. 121 women received the mesh and were followed for 12 months. The goal was to see if the mesh restored normal anatomy, relieved symptoms, and avoided the n…

This study tested whether a computer program (BestDose) could help doctors give the right amount of the antibiotic amikacin to patients with septic shock. The goal was to get drug levels in a safe and effective range after the second dose. 180 patients took part, and researchers …

This study tested whether taking spirulina-silicon supplements could improve blood vessel function in healthy older adults. 120 participants were followed for 6 months to measure artery stiffness and blood pressure. The goal was to see if this supplement could help control age-re…

This study looked at whether extending the time gambling sites stop sending ads after a person voluntarily bans themselves (self-exclusion) helps them gamble less. Over 2,500 adults who self-excluded from online sports betting, poker, or horse racing were randomly assigned to eit…

This study tested a new automatic tool in a small, portable ultrasound device to measure how well the heart pumps blood (ejection fraction). The goal was to see if this tool gives more consistent results than the usual visual method used in emergency rooms. About 60 adults with s…

This study tested whether having a pharmacist and anesthesiologist review medications together before surgery could prevent mistakes. 378 patients scheduled for surgery took part. The goal was to catch and fix errors in their regular medicines to make surgery safer.

This study tested whether placing a special mesh during colostomy surgery can prevent hernias from forming around the stoma. 200 adults having their first colostomy were randomly assigned to get either the mesh or standard surgery without mesh. Researchers checked for hernias eve…

This study looked at whether a numbing medicine called ropivacaine can reduce pain in the first 24 hours after having all four wisdom teeth removed under general anesthesia. 100 adults participated. The goal was to see if ropivacaine works better than a placebo (a shot with no me…

This study looked at whether leaving the gum open after removing all four wisdom teeth causes more pain than closing it with stitches. One hundred people having the surgery under general anesthesia took part. Researchers measured pain two days after surgery to see which approach …

This study looked back at 55 women who had surgery to fix vaginal looseness (called vaginal laxity). The surgery aims to tighten the vaginal opening and improve symptoms like discomfort during sex. Researchers used questionnaires to check sexual health and pain after the operatio…

This study tested whether stimulating nerves on one side or both sides of the body works better for people with overactive bladder that hasn't improved with standard treatments. 55 adults took part, and the main goal was to see if symptoms like frequent urination and sudden urges…

This study looked at whether adding tramadol, nefopam, or an opioid to standard painkillers (paracetamol and ketoprofene) helps adults recover better after shoulder surgery. 92 patients took part, and their recovery quality was measured using a survey. The goal was to find the be…

This study tested a new medical device that uses gentle light therapy to treat vaginal atrophy symptoms in postmenopausal women. The device, a vaginal probe, was tested on 25 women whose symptoms like dryness and pain hadn't improved with standard treatments for over 3 months. Re…

This study followed 40 women with obstetric antiphospholipid syndrome, a condition that can cause pregnancy complications, to see if their brain white matter changes over time. Researchers used MRI scans to measure brain tissue health. The goal was to understand long-term brain e…

This study aimed to count how often violent events happen in the emergency department of a French hospital. Researchers observed 30 patients and staff to track aggressive behaviors and identify patterns. The goal was to gather information to improve safety, not to test a treatmen…

This study used MRI scans and computer-based decision-making tasks to compare brain activity in 40 adults: those who had attempted suicide using violent means, those with mood disorders but no suicide attempt, and healthy volunteers. Researchers looked for differences in brain st…

This study looked at 132 people who needed a central venous catheter (a large IV placed in a deep vein). Doctors used ultrasound to guide the needle, comparing two entry points: under the collarbone (subclavian) or in the armpit (axillary). The goal was to see which approach succ…

This study looked at 1,100 pregnant women to see if having unusual vaginal bacteria (like bacterial vaginosis) makes tears during delivery more likely. Researchers checked medical records for bacteria test results and delivery notes. The goal was to find a link, not to test a tre…

This study followed 392 adults who had planned surgeries to map their pain levels each day for a week. The goal was to see if early pain patterns could predict who develops chronic pain three months later. Researchers used simple pain scores and questionnaires to gather data, aim…

This study tested whether a new automatic tool on an ultrasound machine can measure blood flow from the heart as accurately as the standard manual method. Researchers studied 70 ICU patients with acute circulatory failure (dangerously low blood pressure). The goal was to see if t…

This study looked at whether giving emergency room doctors guidelines for ordering imaging tests (like X-rays or CT scans) helps them choose more relevant exams. Researchers compared test results before and after the guidelines were introduced, involving over 8,500 patients. The …

This study measured how the lower spine and pelvis align when sitting in a straight chair versus an ergonomic chair. Researchers compared 20 people with and without chronic back pain to see if chair type makes a difference. The goal was to gather information, not to test a treatm…

This study looked at 90 men with localized prostate cancer to compare the total cost of robot-assisted prostate removal using the da Vinci system versus traditional open surgery. Researchers tracked all medical expenses over 5 years, including the surgery itself and follow-up car…

This study looked at how people with leg amputations balance while walking. Researchers used special pressure-sensing platforms to measure the symmetry and steadiness of their steps. The goal was to better understand walking patterns after amputation, which could help improve reh…

This study looked at how the body processes antifungal drugs (echinocandins) in 24 adults with septic shock caused by a serious abdominal infection (peritonitis). The goal was to measure drug levels in the blood to help doctors give the right dose. It did not test a new treatment…

This study measured levels of free DNA and nucleosomes in the blood of 137 women to see if these markers differ between those with pregnancy complications (like preeclampsia or blood clots) and healthy women (pregnant or not). The goal was to understand if these markers could hel…

This study looked at how DNA from tumors changes in the blood before, during, and after surgery for breast, prostate, or colon cancer. Thirty adults having curative surgery provided blood samples to track these DNA levels. The goal was to gather basic information that could help …

This study followed about 1,600 women who had repeated early pregnancy loss or a single fetal death, checking if they developed cancer over 17 years. Researchers compared those with antiphospholipid syndrome (a blood clotting disorder), those with other clotting gene changes, and…

This study followed 125 ICU patients who needed a breathing tube and sedation for at least 48 hours. Researchers checked for memory and thinking problems 4 months after leaving the ICU. They also looked at stress, depression, and other factors. The goal was to understand how comm…

This study looked at why some stroke survivors avoid using their weaker arm, even when they have some movement. Researchers tested how the need for force or precision affects this 'non-use.' 53 participants completed reaching tasks to measure when and why they chose not to use th…

This study looked at how the body processes the drug sunitinib in people with kidney cancer that has spread. Researchers measured drug levels in the blood and checked for genetic differences that might explain why levels vary. The goal was to understand why some patients get more…

This study compared two special mattresses (Nimbus 3 and Summit) designed to prevent bedsores in people who are bedridden. Researchers measured pressure on the skin of 31 participants to see which mattress distributed pressure better. The goal was to find out if one mattress was …

This study looked at how hospitals in southern France treat spleen injuries caused by accidents or other trauma. Researchers followed 93 patients to track deaths, complications, and how long they stayed in the hospital. The goal was to understand current treatment patterns and co…

This study looked at DNA from 400 people with ALS and 400 healthy people to see if certain gene variations related to vitamin D are more common in ALS. The goal was to learn more about the disease, not to test a new treatment. No direct benefit to participants was expected.

This study looked at whether a blood test done before hip or knee replacement surgery can predict the risk of developing deep vein thrombosis (a dangerous blood clot). Researchers measured thrombin generation in 146 adults. The goal was to see if the test could identify who is at…

This study explored whether the proteins from gut bacteria differ between bladder cancer patients who respond to immunotherapy and those who do not. Researchers collected stool and blood samples from 40 patients to compare these protein profiles. The goal was to find a way to pre…

This study compared a new magnetic device (Needle-pilot) with standard ultrasound for placing central lines in the subclavian vein. 51 doctors and trainees practiced on a mannequin torso. The main goal was to see if the device shortened the time to successfully draw blood. The st…

This study looked at whether giving less fluid (other than the fluids needed to treat shock) to ICU patients with septic shock could reduce dangerous fluid buildup. 50 patients were split into two groups: one got standard care, the other got a strict fluid-minimizing plan. The go…

This study looked at how well children under 16 take their anti-infective medicines after being discharged from the hospital. Researchers followed 75 kids for one month to see if they took their prescribed antibiotics correctly. The goal is to understand compliance rates and help…

This study tested whether a special 'remission' consultation helps women who finished treatment for early-stage breast cancer. Fifty patients completed surveys about their quality of life, body image, and distress at 3, 6, and 12 months after the consultation. The goal was to see…

This study looked at 50 adults with septic shock to see if a special heart ultrasound called strain echocardiography can help predict outcomes. Researchers measured heart function within the first day of shock and tracked survival in the ICU. The goal was to learn more about how …

This study observed 20 stroke patients who had weakness lifting their front foot while walking. Researchers measured the timing of when patients' heels hit the ground to help improve how electrical stimulation is triggered to lift the foot. The goal was to gather data, not to tes…

This study aimed to create a tool that helps doctors decide which patients with severe acute kidney injury should see a kidney specialist after leaving the hospital. Researchers looked at 319 patients who needed dialysis for kidney injury and tracked their recovery. The goal was …

This study looked at 31 elderly people living in nursing homes who take blood thinners (vitamin K antagonists). Researchers compared a simple finger-prick test to the usual blood-draw test for measuring how thin the blood is. The goal was to see if the finger-prick test leads to …

This study looked at 60 adults with septic shock in the ICU to see if their intestines were leaking bacteria into the blood. Researchers measured specific DNA markers and gut health proteins over seven days. The goal was to better understand how gut problems might make septic sho…

This study tested whether high doses of vitamin D can change the immune system in healthy adults. Researchers gave 56 participants either vitamin D or a placebo for 3 months and measured different types of immune cells in their blood. The goal was to understand how vitamin D migh…

This study looked at 40 stroke patients with arm muscle stiffness (spasticity) who were treated with botulinum toxin (Botox). Researchers measured tiny electrical signals in the muscle to see how they change over time and whether they can predict when the treatment effect wears o…

This study looked at 206 patients who had carotid artery surgery to see if the position of the hyoid bone (a small bone in the neck) near the carotid artery is linked to artery narrowing and stroke. Researchers used CT scans to measure the distance and angle between the hyoid bon…

This study looked at 104 adults arriving at the emergency room with severe breathing trouble. Doctors used an ultrasound to measure how far the diaphragm (the main breathing muscle) moved. The goal was to see if this measurement could predict who would need a breathing machine wi…

This study looked at whether certain immune cells can make the body less responsive to insulin, a hormone that controls blood sugar. Researchers took blood samples from 30 adults and tested how their immune cells affected liver cells in a lab. The goal was to better understand ho…