Centre Hospitalier Universitaire De Nīmes
Clinical trials sponsored by Centre Hospitalier Universitaire De Nīmes, explained in plain language.
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6-Year study examines whether a simple strip can keep stress incontinence under control
Disease control CompletedThis study evaluates the long-term safety and effectiveness of Advantage® strips, a type of surgical tape, for treating stress urinary incontinence in women. Researchers are reviewing the medical records of 500 women who received the strip between 2012 and 2015, with an average f…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Kidney alert team may cut deaths in hospital patients
Disease control CompletedThis study tested whether quickly alerting a kidney specialist team when hospitalized patients show signs of severe kidney disease could improve survival. Over 1,100 patients in France were included. The team of a nephrologist and pharmacist would help manage care during the hosp…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Fiber fix? study tests if a simple supplement boosts arthritis Drug's power
Disease control CompletedThis study tested whether adding a daily fiber supplement (inulin) to standard anti-IL-17 therapy could improve gut bacteria balance and treatment response in 76 adults with axial spondyloarthritis. Participants took either fiber or a placebo powder for three months. The main goa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Daily ultrasound could keep heart failure patients out of the hospital
Disease control CompletedThis study tested whether daily bedside ultrasound scans help doctors better adjust treatment for people hospitalized with acute heart failure. The goal was to see if this approach reduces the number of patients readmitted within 30 days. The study involved 250 adults with heart …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Can a 9-Month ad blackout help problem gamblers stay away?
Disease control CompletedThis study looked at whether extending the time gambling websites stop sending ads after a person voluntarily bans themselves helps them gamble less. Over 2,500 adults who self-excluded from online sports betting, poker, or horse racing were randomly assigned to either the standa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New hope for endometriosis patients: simpler Egg-Freezing protocol shows promise
Disease control CompletedThis study looked at 130 women with endometriosis who froze their eggs. It compared a drug called dienogest against standard hormone treatments to see if it could collect a similar number of mature eggs. The goal is to find a simpler, effective option for fertility preservation i…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Smart software aims to perfect antibiotic dosing in septic shock
Disease control CompletedThis study tested whether a computer program called BestDose could help doctors give the right amount of the antibiotic amikacin to patients with septic shock. The goal was to get drug levels in the ideal range after the second dose. 180 patients took part, and researchers checke…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Could HIV drugs help clear psoriasis? tiny study explores the idea
Disease control CompletedThis small study tested whether a short course of HIV drugs (emtricitabine and tenofovir) could reduce inflammation in people with plaque psoriasis. Only 8 people took part, and the main goal was to see changes in certain markers in skin biopsies. The study is complete, but resul…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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AI and cap team up to spot hidden colon polyps
Disease control CompletedThis study tested whether using an artificial intelligence system (GI GENIUS) together with a special cap (ENDOCUFF VISION) on the colonoscope helps doctors find more precancerous polyps during colonoscopy than using either tool alone. About 481 adults undergoing screening or fol…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Safer dialysis for bleeding patients? citrate vs. heparin tested
Disease control CompletedThis completed trial tested two ways to prevent blood clots during dialysis in 60 patients at high risk of bleeding. One method used a special blood thinner called citrate, the other used a low dose of standard heparin. The goal was to see which approach allowed dialysis to run l…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Tiny beads choke off prostate tumors in early test
Disease control CompletedThis small pilot study tested a procedure called prostatic arterial embolization in 10 men with low-risk, one-sided prostate cancer who were already on active surveillance. The idea was to block the artery feeding the tumor, starving it of blood. Researchers checked for side effe…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Does triggering ovulation boost IVF success? new study investigates
Disease control CompletedThis study looked at 103 women undergoing frozen embryo transfer to see if letting them ovulate naturally or using a hormone shot (HCG) to trigger ovulation leads to more pregnancies. The main goal was to compare pregnancy rates between the two groups. Results help doctors choose…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Can a Low-Dose immune booster tame ALS inflammation?
Disease control CompletedThis phase 2 trial tested whether low-dose interleukin-2 (IL-2) can help control nerve inflammation in people newly diagnosed with ALS. Over 18 months, 304 participants received either IL-2 or a placebo, alongside standard riluzole treatment. The goal was to see if boosting regul…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Spirulina-Silicon pills tested for artery health in seniors
Disease control CompletedThis study tested whether taking a daily spirulina supplement with added silicon could improve artery function in healthy older adults. Researchers measured blood vessel flexibility and pressure in 120 participants over six months. The goal was to see if this natural supplement c…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Talking to a pharmacist about your COPD inhalers might keep you out of the hospital
Disease control CompletedThis study tested whether having a pharmacist teach people with COPD about their medications could reduce sudden worsening of symptoms. 174 adults with moderate to severe COPD were given a 20-minute education session either at the hospital or at their local pharmacy, plus a 10-mi…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Robot vs. surgeon: which surgery is safer for pelvic organ prolapse?
Disease control CompletedThis study compared two types of minimally invasive surgery for pelvic organ prolapse in 365 women. One group had robot-assisted surgery, while the other had standard laparoscopic surgery without a robot. The main goal was to see which approach had fewer complications within 30 d…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Dialysis showdown: which method cleans blood better in ICU patients?
Disease control CompletedThis study tested two types of dialysis—hemodiafiltration and hemofiltration—in 163 ICU patients with acute kidney failure. Patients received both methods in alternating order, and researchers measured how well each reduced waste products like urea in the blood. The goal was to s…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Mesh vs. no mesh: which bladder prolapse surgery holds up better over time?
Disease control CompletedThis study looked at 75 women who had surgery for bladder prolapse (a condition where the bladder bulges into the vagina). It compared two techniques: one using a mesh support and one without. The goal was to see which method works better over 5 to 8 years, focusing on whether th…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Mesh study aims to fix pelvic organ prolapse
Disease control CompletedThis study tested a special mesh (Uphold LITE) to treat uterine prolapse, a condition where the uterus drops into the vagina. 121 women received the mesh and were followed for 12 months. The goal was to see if the mesh could restore normal anatomy and relieve symptoms without nee…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Vitamin d pills tested for obese Teens' heart health
Disease control CompletedThis study looked at whether giving vitamin D supplements to obese teenagers, along with a healthy diet and exercise program, could improve how well their blood vessels work. 49 teens took either vitamin D or a placebo for 90 days. The main goal was to see changes in blood vessel…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Immune tweak shows promise for ALS in early trial
Disease control CompletedThis phase II study tested whether low doses of interleukin-2 (IL-2) can safely boost regulatory T cells in people with amyotrophic lateral sclerosis (ALS). 36 participants received either IL-2 or a placebo for five days. The goal was to see if this immune-modulating approach cou…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New pulse monitor could sharpen fluid decisions in major surgery
Diagnosis CompletedThis study tests whether a new pulse contour device can accurately detect increases in stroke volume during a fluid challenge in patients undergoing high-risk abdominal surgery. Researchers will compare the device's readings to those from transthoracic echocardiography. The goal …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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New blood test aims to spot prostate cancer cells earlier
Diagnosis CompletedThis study tested a new blood test called EPISPOT to find prostate cancer cells in the blood of 361 men with localized prostate cancer before they received any treatment. The goal was to see if this test could predict remission better than an existing test called CellSearch. The …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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New 3D scan could replace Radiation-Heavy CT for spine bone checks
Diagnosis CompletedThis study tested a new imaging method called 3D-DXA to measure bone density in the spine, comparing it to standard CT scans. Researchers enrolled 120 adults who already needed a CT scan. The goal was to see if the 3D-DXA technique, which uses less radiation, could give equally a…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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Grinding up samples: a better way to spot bone infections?
Diagnosis CompletedThis study tested two ways of preparing tissue samples to find bacteria in bone and joint infections. One method grinds the sample, while the other uses standard techniques. Researchers wanted to see which method is more accurate at diagnosing infections. The study involved 122 p…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Jun 27, 2026 09:01 UTC
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New ultra Low-Dose CT scanner could replace X-Rays for broken bones
Diagnosis CompletedThis study tested whether a new ultra low-dose CT scanner can find bone fractures as well as standard X-rays, but with less radiation. Over 500 emergency patients with suspected breaks in the spine, pelvis, or limbs were scanned using both methods. The goal was to see if the low-…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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PET scan breakthrough: spotting brain tumors vs. Look-Alikes
Diagnosis CompletedThis study looked at whether a type of PET scan called FDOPA-PET can help doctors tell the difference between brain tumors and non-cancerous brain lesions. Researchers reviewed scans from 74 patients with suspected brain tumors. They measured how much of the tracer the lesions to…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Jun 27, 2026 08:01 UTC
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Ultrasound may spot rare nerve disease CANVAS
Diagnosis CompletedThis study tested whether ultrasound of the nerves can help diagnose CANVAS, a rare genetic disorder that causes balance problems, nerve damage, and dizziness. Researchers measured nerve size in 35 people with confirmed CANVAS and compared them to healthy individuals. The goal wa…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Jun 27, 2026 08:01 UTC
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ER ultrasound may predict who needs a ventilator
Diagnosis CompletedThis study looked at whether a quick diaphragm ultrasound in the emergency room can predict which patients with severe breathing problems will need a ventilator within the first four hours. Researchers measured diaphragm movement in 104 adults upon arrival and again four hours la…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Jun 27, 2026 07:58 UTC
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Blood test may predict kidney danger in muscle injury patients
Diagnosis CompletedThis study looked at 197 emergency room patients with rhabdomyolysis (severe muscle breakdown) to see if a blood test for a protein called NGAL could predict who would develop acute kidney failure within 48 hours. The goal is to help doctors identify high-risk patients earlier an…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Jun 27, 2026 07:57 UTC
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New french test aims to spot delirium in seniors faster
Diagnosis CompletedThis study tested a French version of the Confusion Assessment Method (CAM), a tool to quickly diagnose acute confusion (delirium) in elderly patients. Researchers compared the CAM results with a psychiatrist's diagnosis using standard criteria. The goal was to see how accurate t…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Jun 27, 2026 07:57 UTC
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Teamwork cuts drug errors before surgery
Prevention CompletedThis study tested whether having a pharmacist and anesthesiologist review medications together before surgery could prevent mistakes. 378 patients scheduled for surgery took part. The goal was to catch and fix errors in their regular medicines before the operation.
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Prevention
Last updated Jun 27, 2026 08:03 UTC
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Pharmacist teamwork boosts pneumonia vaccine rates in hospitals
Prevention CompletedThis study tested whether a structured collaboration between pharmacists and doctors could improve pneumococcal vaccination rates in patients at high risk for infection. Over 600 hospitalized adults with chronic conditions or weakened immune systems took part. The pharmacist revi…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Prevention
Last updated Jun 27, 2026 08:01 UTC
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Mesh may stop hernias after colostomy
Prevention CompletedThis study tested whether placing a special mesh during colostomy creation can prevent hernias from forming around the stoma. 200 patients having their first colostomy were randomly assigned to get the mesh or not. They were checked every three months for two years to see if a he…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Prevention
Last updated Jun 27, 2026 08:00 UTC
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Cranberry capsules tested to stop catheter infections after surgery
Prevention CompletedThis study looked at whether cranberry gel capsules can prevent E. coli infections from urinary catheters placed during pelvic surgery. About 270 adults took part. The idea was that cranberry might stop bacteria from sticking to the catheter, reducing infection risk.
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Prevention
Last updated Jun 27, 2026 07:58 UTC
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Could a cocktail of Non-Opioid drugs replace Morphine-Like painkillers in the ICU?
Symptom relief CompletedThis trial investigates whether a combination of non-opioid pain medications (paracetamol, nefopam, tramadol, and ketamine) can effectively manage pain in intensive care unit patients who need a breathing machine, while reducing the use of the opioid remifentanil. The study invol…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jul 01, 2026 20:00 UTC
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Could a simple drug combo cut morphine use after colon surgery?
Symptom relief CompletedThis study looked at whether adding the drug nefopam to standard pain relief (morphine and paracetamol) can reduce the amount of morphine needed after major colon surgery. 80 adults having planned surgery for colon cancer or diverticulosis took part. The main goal was to measure …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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New injection technique may offer better knee pain relief
Symptom relief CompletedThis study tested whether injecting a steroid (betamethasone) directly into the torn meniscus of the knee provides better pain relief and function than the standard injection into the joint space. 70 people with stable degenerative meniscal tears were randomly assigned to one of …
Phase: PHASE1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Virtual mirror therapy shows promise for rare pain condition
Symptom relief CompletedThis study tested whether adding augmented reality mirror therapy (ARMT) to standard physical and occupational therapy helps people with complex regional pain syndrome (CRPS) of the upper limb. Seven participants received both conventional therapy and ARMT sessions over a month. …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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New device aims to make ICU catheter insertion faster and safer
Symptom relief CompletedThis study tests a new needle-steering device that helps doctors place central lines (large IVs) in ICU patients. The device uses special software and a magnetized needle to guide placement more accurately than standard ultrasound. Researchers will compare success rates and compl…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Talking it out: study tests 'Remission' consultation for breast cancer patients
Symptom relief CompletedThis study looked at whether a special 'remission' consultation with a psychotherapist can improve quality of life for women who have finished treatment for localized breast cancer. Fifty women who completed chemotherapy or radiotherapy in the last six months were offered this ta…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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New light probe offers hope for menopause vaginal pain
Symptom relief CompletedThis study tested a new vaginal probe that uses special lights to treat vaginal atrophy in 25 postmenopausal women who had not been helped by other treatments. The probe aims to reduce pain and dryness by stimulating natural tissue repair. The main goal was to check safety and se…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Which painkiller works best after shoulder surgery? new study compares options
Symptom relief CompletedThis study looked at adding tramadol, nefopam, or opioids to standard painkillers (paracetamol and ketoprofene) for adults recovering from shoulder surgery. 92 patients were enrolled, and their recovery quality was measured using a survey. The goal was to find the best oral pain …
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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New anesthesia mix may ease pain after hand surgery
Symptom relief CompletedThis study tested two local anesthesia methods for hand, wrist, or elbow surgery. One used lidocaine alone, the other added ropivacaine for longer pain relief. 91 adults participated. Researchers measured pain and recovery quality 48 hours after surgery to see if the combination …
Phase: PHASE1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Quick brain game may boost exercise in heart rehab
Symptom relief CompletedThis study tested whether a short, 15-minute brain-training task (evaluative conditioning) could help heart attack survivors exercise at a higher intensity during cardiac rehab. Twenty-four patients were split into two groups: one received training linking physical activity with …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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New wheelchair adapts to spasms, promises better comfort and safety
Symptom relief CompletedThis study tested a special wheelchair called NETTI that can switch between a dynamic mode (which moves with the user) and a static mode. Four people who have frequent involuntary muscle spasms that cause them to slide forward in their chair took part. Researchers measured how mu…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Ultrasound could take the ouch out of nerve exams
Symptom relief CompletedThis study tested whether using ultrasound during a nerve test (electroneuromyography) can reduce the electrical stimulation needed, making the test less painful. 290 adults were randomly assigned to receive the test with or without ultrasound guidance. The goal was to see if ult…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Can surgery improve sexual health after childbirth? new study investigates
Symptom relief CompletedThis study looks at how well surgical perineal repair works for women with vaginal laxity, a condition where the vagina feels loose, often after childbirth. Researchers reviewed the records of 55 women who had the surgery between 2012 and 2020. They used a questionnaire to measur…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Electric hand device shows promise for stroke patients
Symptom relief CompletedThis study tested a device that uses mild electrical pulses to stimulate finger muscles in stroke survivors who cannot open their hand. The goal was to see if it helps them grasp, move, and release objects like a glass or spoon. Eleven people with chronic stroke participated, and…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Back surgery pain relief: simple nerve block cuts morphine use?
Symptom relief CompletedThis study tested whether a nerve block using the drug ropivacaine could reduce pain and the need for morphine after lumbar spine surgery. Fifty adults having back surgery received either the nerve block or a placebo (salt water) in addition to standard anesthesia. The goal was t…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Ketamine shows promise for rapid relief of suicidal ideation
Symptom relief CompletedThis study tested whether ketamine, given as two infusions, can quickly reduce suicidal thoughts in 156 hospitalized patients at high risk for suicide. The main goal was to see if suicidal ideas resolved within 24 hours after the second dose. The approach aims to provide fast, sh…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Can a custom diet help MS patients strengthen bones?
Symptom relief CompletedThis study tested whether personalized dietary advice from a dietitian helps people with multiple sclerosis (MS) get more calcium in their diet. 182 MS patients who could still walk were split into two groups: one received one-on-one dietitian sessions, the other got a standard a…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Simpler prostate procedure may help elderly men ditch catheters
Symptom relief CompletedThis study looked at 50 elderly men with an enlarged prostate who needed a urinary catheter. Doctors compared blocking blood flow to one side of the prostate versus both sides. The goal was to see if the simpler one-sided procedure could help patients stop using catheters just as…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Skip the stitches? wisdom tooth study tests Pain-Free recovery
Symptom relief CompletedThis study looked at whether leaving the gum open after removing wisdom teeth causes less pain than stitching it closed. 100 people having all four wisdom teeth out under general anesthesia were randomly assigned to get stitches or not. The main goal was to measure pain two days …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Nerve zap showdown: one side or both for bladder relief?
Symptom relief CompletedThis study tested whether stimulating nerves on one side or both sides of the body works better for people with overactive bladder that hasn't improved with standard treatments. 55 adults were randomly assigned to receive either unilateral or bilateral nerve stimulation. The goal…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Can a simple injection ease menopause pain? new study investigates
Symptom relief CompletedThis small pilot study tested whether injecting a gel-like substance (hyaluronic acid) into the vaginal area could help menopausal women with pain during sex and vaginal dryness. Twenty women received the injections and were followed for 8 weeks. The main goal was to see if the v…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Laughing gas may help frozen shoulder patients move better during therapy
Symptom relief CompletedThis study looked at whether inhaling a mixture of oxygen and nitrous oxide (sometimes called laughing gas) during physical therapy helps people with frozen shoulder. 75 adults with frozen shoulder took part. Some received the gas mix during therapy, while others inhaled a placeb…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Which breathing tube causes the least pain? study compares three devices
Symptom relief CompletedThis study tested three different breathing devices used during short surgeries to see which one causes the least sore throat afterward. Over 500 adults took part, and researchers measured pain, how easy the device was to place, and how many tries it took. The goal was to find a …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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New painkiller may cut side effects after hip surgery
Symptom relief CompletedThis study tested whether a pain medicine called oxycodone causes fewer side effects than morphine after hip replacement surgery. About 246 adults took part. The goal was to see if oxycodone reduces problems like nausea, vomiting, itching, and breathing trouble by half. The resul…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Hypnosis may help kids avoid pain gas during stitches
Symptom relief CompletedThis study tested whether hypnosis, with MEOPA (a pain-relieving gas) available if needed, works as well as MEOPA alone for controlling pain in children getting stitches. Sixty children in the emergency department were randomly assigned to one of two groups. The goal was to see i…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Wisdom tooth pain relief put to the test: ropivacaine vs. placebo
Symptom relief CompletedThis study looked at whether a local anesthetic called ropivacaine can reduce pain after having all four wisdom teeth removed under general anesthesia. 100 adults took part, receiving either ropivacaine or a placebo. The main goal was to measure pain levels over the first 24 hour…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Heart-Safe anesthesia: drug may tame dangerous racing pulse
Symptom relief CompletedThis study tested whether adding remifentanil, a fast-acting painkiller, to standard emergency anesthesia could prevent a dangerously fast heart rate in fragile patients. 75 adults needing rapid-sequence intubation received either a low or high dose of remifentanil or a placebo. …
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Mouth bacteria may reveal cavity risk
Knowledge-focused CompletedThis study examines how different types of bacteria in the mouth are linked to the severity of dental cavities. Researchers will collect saliva and plaque samples from 56 people aged 3 to 45 and grade their cavities using a standard scoring system. The goal is to better understan…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jul 01, 2026 20:00 UTC
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Colostomy irrigation: does it improve quality of life?
Knowledge-focused CompletedThis completed study from France surveyed over 1100 adults with a colostomy to see how many use colonic irrigation and whether it improves their quality of life. Researchers also looked at why some people don't use it or stop, and how they practice it. The goal is to better under…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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ER study reveals critical care admission patterns in 1,629 patients
Knowledge-focused CompletedThis study observed over 1,600 adults in French emergency rooms to understand how patients are managed in the resuscitation area and whether being admitted directly to that area versus later affects their need for intensive care within 24 hours. Researchers recorded patient detai…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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900 Men's quality of life checked years after prostate cancer diagnosis
Knowledge-focused CompletedThis study looks at how prostate cancer and its treatment affect quality of life three years after diagnosis. Researchers compared 900 men with prostate cancer to cancer-free men of the same age. The goal is to understand what life is like after treatment and whether patients ret…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Pharmacists on the ward: a prescription for savings?
Knowledge-focused CompletedThis study tested whether having a clinical pharmacist work with doctors in two hospital units (infectious diseases and internal medicine) could improve the quality of prescriptions and reduce costs. Researchers tracked 500 patients to see if the pharmacist's involvement led to f…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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ICU antibiotic dosing study: do higher doses hit the mark?
Knowledge-focused CompletedThis study looked at whether giving higher doses of two common antibiotics (amikacin and gentamicin) to ICU patients with severe sepsis helps achieve the right levels in the blood. Researchers enrolled 63 critically ill adults to measure if the higher doses reached target concent…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Can simple tests forecast brain recovery after cardiac arrest?
Knowledge-focused CompletedThis study looked at 130 adults who survived a cardiac arrest outside the hospital and were treated with cooling therapy. Researchers measured two simple tests—a blood protein level and a motor response score—to see if they could predict brain function 6 months later. The goal is…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Hepatitis c study tests whether a patient registry is possible in vietnam
Knowledge-focused CompletedThis study looked at whether it's possible to create a group of people with hepatitis C in Hai Phong, Vietnam, for future research. 300 adults with active hepatitis C took part. The goal was to see how many patients could be enrolled and how much information could be collected, n…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Why do parents of disabled kids suffer back pain? a new study seeks answers
Knowledge-focused CompletedThis completed study interviewed 13 parents or carers of children with severe motor disabilities who experience spinal pain. The goal was to understand their daily challenges and what factors contribute to their back pain. Researchers hope this knowledge will help create better s…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Quick hormone test may spot thyroid surgery complication risk
Knowledge-focused CompletedThis study looked at 300 patients who had their thyroid removed to see if a parathyroid hormone (PTH) test right after surgery could predict low calcium levels. The goal was to find a threshold that rules out hypoparathyroidism. Researchers reviewed past medical records to analyz…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Does a common anesthesia drug affect newborns? new study investigates
Knowledge-focused CompletedThis completed study reviewed records of 265 women who had a cesarean section under spinal anesthesia. Researchers compared newborns whose mothers received norepinephrine (a drug to maintain blood pressure) to those who did not. The main focus was on umbilical cord lactate levels…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New guide aims to help myeloma patients stick to their pill regimen
Knowledge-focused CompletedThis study aims to develop a standardized reference guide for pharmacists to use during initial consultations with multiple myeloma patients starting oral chemotherapy. The goal is to provide clear, consistent information that helps patients understand and follow their treatment …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Can a pharmacy bundle shorten ICU stays and cut costs?
Knowledge-focused CompletedThis study looked at whether adding a set of pharmacist-led activities (a 'clinical pharmacy bundle') could improve outcomes for nearly 2,800 ICU patients in two French hospitals. Researchers compared patient data before and after the bundle was introduced, focusing on length of …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Can a simple questionnaire capture the real impact of back pain?
Knowledge-focused CompletedThis study evaluates the SF-6D, a questionnaire that measures health-related quality of life, in people with early inflammatory back pain (symptoms for 3 months to 3 years). Researchers will check if the tool is reliable, sensitive to changes over time, and how factors like age, …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Scientists hunt for proteins that predict breast cancer spread
Knowledge-focused CompletedThis completed study analyzed tissue samples from 108 breast cancer patients to identify proteins linked to early cancer invasion. The goal was to find markers that could help assess the risk of tumor spread in patients without lymph node involvement. Researchers focused on listi…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New study aims to predict early death risk in elderly kidney patients
Knowledge-focused CompletedThis study follows people over 75 with advanced chronic kidney disease to better understand their health and treatment paths. Researchers want to create a tool that predicts which patients are at high risk of dying soon after starting dialysis. The goal is to help patients, famil…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Gene clue may help spot hidden brain vessel condition
Knowledge-focused CompletedThis study looks at whether a specific gene variant (ApoE4) is more common in people with certain brain MRI patterns that suggest cerebral amyloid angiopathy (CAA), a condition where proteins build up in brain blood vessels. Researchers will analyze genetic samples from 100 patie…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Study checks if antibiotic dosing hits the mark in ICU sepsis patients
Knowledge-focused CompletedThis study examines whether intensive care unit (ICU) patients being treated for sepsis receive aminoglycoside antibiotics at doses that achieve the recommended peak concentration in the blood. Researchers will measure drug levels after the first and later doses in about 90 adult…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Hospital reviews 5 years of bacillus cereus cases to spot deadly risks
Knowledge-focused CompletedThis study looked back at 76 adult patients diagnosed with a Bacillus cereus infection at a French hospital between 2008 and 2012. Researchers analyzed patient characteristics, lab results, and treatments to better understand the infection and find risk factors for death in those…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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A quick sleep check could help prevent relapse in alcohol recovery
Knowledge-focused CompletedSleep problems affect up to 90% of people with alcohol dependence and often lead to relapse. This study tests whether a short questionnaire called the Short Sleep Index (SSI) can reliably measure sleep quality compared to a longer, standard sleep questionnaire. Researchers will a…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Spine surgery Patients' data collected to improve future care
Knowledge-focused CompletedThis study gathered information from 193 adults who had surgery or orthopedic treatment for spine problems. Researchers collected clinical, functional, and social data to create a detailed database. The goal was to better understand patient outcomes and standardize how data is co…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Tiny brain strokes often invisible on later scans, study finds
Knowledge-focused CompletedThis study looked at 59 patients who had very small strokes (called microinfarctions) in either the cerebrum or cerebellum. Researchers wanted to see how often these tiny spots could still be seen on follow-up MRI scans done in routine care. The goal was to understand if MRI is b…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Decades of data: does this bladder surgery stand the test of time for spinal cord injury?
Knowledge-focused CompletedThis completed study from France reviewed the long-term results of a surgery called continent cutaneous urinary diversion in 70 spinal cord injury patients. The surgery creates a new way to drain urine through the belly when patients cannot use a catheter normally. Researchers co…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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MRI reveals Acupuncture's brain impact in migraine sufferers
Knowledge-focused CompletedThis study looked at how acupuncture affects the brain in people with migraine without aura. Forty adults received either real acupuncture or a sham (fake) version, and their brains were scanned with MRI before and after treatment. The goal was to see if real acupuncture causes d…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Wheelchair positioning may boost quality of life, small study hints
Knowledge-focused CompletedThis study looked at whether a specialized wheelchair positioning consultation can improve daily life for people who have used a wheelchair for at least six months. Ten participants were assessed before and after the consultation using a scale from the World Health Organization. …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Tiny bacteria, big impact: could vaginal microbes determine surgical success?
Knowledge-focused CompletedThis study looks at whether the types of bacteria living in the vagina influence how well women recover after surgery for pelvic organ prolapse using a vaginal mesh. Researchers will analyze stored samples from 41 women who had this surgery, comparing those who had complications …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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French study tracks Real-World use of TNF blockers in early arthritis
Knowledge-focused CompletedThis study followed 813 people with early rheumatoid arthritis in France to see how often and why doctors prescribe TNF blockers. Researchers tracked symptoms, joint damage, and treatment success over 5 years. The goal was to learn which patients benefit most and how well doctors…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Hospital check: are women getting bone treatment after major breaks?
Knowledge-focused CompletedThis study checked whether women over 50 who had severe osteoporotic fractures (like hip or spine breaks) were scheduled for osteoporosis treatment at Nîmes University Hospital. Researchers reviewed hospital records of 500 patients to see if treatment was planned. The goal was to…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Could natural immune cells help fight leukemia drug resistance?
Knowledge-focused CompletedThis completed study from France examined whether a specific type of immune cell (innate CD8+ T cells) is linked to how quickly resistance mutations develop in patients with chronic myeloid leukemia or Philadelphia-positive acute lymphoblastic leukemia. Researchers analyzed blood…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New insights on TNF blockers alone for early arthritis
Knowledge-focused CompletedThis study followed 813 people with early rheumatoid arthritis in France to see how often doctors prescribe TNF blockers alone (without other arthritis drugs) and how well they work. Researchers tracked symptoms, joint damage, and how long patients stayed on treatment over 5 year…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Scientists create new tools to fight rare urinary tract cancer
Knowledge-focused CompletedThis study aimed to create lab models of a rare and aggressive cancer of the upper urinary tract. Researchers took tumor samples from 20 patients and tried to grow them in mice and on chicken egg membranes. The goal was to develop tools to test new treatments for this cancer, whi…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New MRI technique could help surgeons avoid nerve damage
Knowledge-focused CompletedThis study tested whether a special MRI technique called diffusion tensor imaging (DTI) can map pelvic nerves as well as a standard 3D MRI. 20 adults having a pelvic MRI for any reason took part. The goal was to see if DTI gives a clearer picture of key nerves, which could help s…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Can ultrasound help doctors give the right amount of fluids in septic shock?
Knowledge-focused CompletedThis study tested whether a specific ultrasound-based algorithm could help doctors better manage fluids in patients with septic shock. The trial involved 136 intensive care patients and compared the algorithm to standard care over the first 4 days. The goal was to see if the algo…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Mind over pain: study probes how catastrophic thinking worsens chronic pain
Knowledge-focused CompletedThis study looks at how 'pain catastrophizing'—a pattern of negative thinking about pain—affects people with chronic pain in a hospital rheumatology unit. Researchers aim to understand what drives this thinking and how it impacts sleep and medication use. The findings could help …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Silent brain clues: new study hunts for early warning signs of multiple sclerosis
Knowledge-focused CompletedThis study looked at 320 people whose brain scans showed signs that sometimes lead to multiple sclerosis (MS), even though they had no symptoms. Researchers analyzed blood and spinal fluid samples to find biological markers that could predict whether these silent signs would turn…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Brain scan study reveals hidden differences in two common blood vessel diseases
Knowledge-focused CompletedThis study looked at MRI scans from 72 people with two common types of small vessel disease in the brain: hypertensive arteriopathy and cerebral amyloid angiopathy. Researchers focused on tiny fluid-filled spaces in a part of the brain called the dentate nucleus. The goal was to …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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MRI reveals brain differences in violent suicide attempts
Knowledge-focused CompletedThis study used MRI brain scans and computer tasks to understand how people who attempted suicide make decisions. Researchers compared three groups: those who used violent means, those who used non-violent means, and healthy volunteers. The goal was to find brain activity pattern…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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New test may help doctors pick the right antibiotic for diabetic foot wounds
Knowledge-focused CompletedThis study looked at a new lab test called Antibiofilmogramme for people with diabetic foot infections caused by Staph bacteria. The goal was to see if the test could help doctors choose antibiotics that work better. 33 adults took part, and the study did not change their regular…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Can a smart gadget keep you out of the hospital after surgery?
Knowledge-focused CompletedThis study tested whether a device called SMART ANGEL, which tracks heart rate, blood pressure, oxygen levels, and symptoms like pain and nausea at home, could reduce unplanned hospital visits, doctor calls, or extra prescriptions after major or intermediate outpatient surgery. O…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Gut leaks in septic shock: a closer look at hidden infections
Knowledge-focused CompletedThis study looked at 60 intensive care patients with septic shock to see if their intestines become leaky, allowing bacteria to enter the blood. Researchers measured specific markers in the blood over a week to track gut damage and changes in gut bacteria. The goal was to better …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New device aims to cut spine screw errors in half
Knowledge-focused CompletedThis study tested a new lightweight device called PYTHEAS ODYSSEE that helps surgeons place screws in the spine more accurately. Fourteen adults having spine surgery used the device to guide screw placement. The goal was to see if the device reduces screw misplacement and is safe…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Mind over matter: mental rehearsal boosts IV skills in med students
Knowledge-focused CompletedThis study tested whether a mental imagery session—where students vividly imagine placing an IV—improves their success rate on a practice mannequin. Ninety-six fifth-year medical students took part. The goal is to find a safer, faster way to teach this common but tricky procedure…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Which exercise is best after a heart attack? study seeks answers
Knowledge-focused CompletedThis study compared two types of exercise training for people who had a heart attack: continuous moderate exercise and intermittent high-intensity exercise. One hundred participants completed an 8-week program, and researchers used ultrasound to measure changes in heart function.…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New program helps men with advanced prostate cancer understand their treatment
Knowledge-focused CompletedThis study tested a new education program for men with metastatic prostate cancer who are taking next-generation hormone therapy. The program aimed to help patients better understand their disease, stick to their medication, and improve their quality of life. 18 patients took par…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Blood test may predict clot risk after joint surgery
Knowledge-focused CompletedThis study looked at whether a blood test done before hip or knee replacement surgery can predict the risk of developing deep vein thrombosis (DVT), a dangerous blood clot. Researchers measured thrombin generation in 146 patients. The goal was to see if the test could identify wh…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Blood test may spot polyp cells that signal cancer risk
Knowledge-focused CompletedThis study tested whether a blood test can find tumor cells or substances released by intestinal polyps. Researchers compared blood samples from 120 people with and without polyps during a colonoscopy. The goal is to see if these markers could help predict or monitor cancer sprea…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Brain scans reveal hidden damage years after pregnancy complication
Knowledge-focused CompletedThis study uses special MRI scans to see if the white matter in the brain gets worse over time in women who have obstetric antiphospholipid syndrome, a condition that can cause pregnancy loss. Researchers will compare brain images from 40 women who were part of an earlier study. …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Rare stroke cause gets closer look in new study
Knowledge-focused CompletedThis study looked at 79 people with a rare type of stroke caused by calcified particles traveling to the brain. Researchers used CT scans to describe the size, location, and density of these particles, and compared patients' medical histories and risk factors. The goal was to bet…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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ER bias test: does race affect pain prescriptions for sickle cell?
Knowledge-focused CompletedThis study asked over 1,000 emergency doctors in Europe what they would prescribe for a patient with sudden belly pain. The patient's race was changed to see if it affected the doctor's choice to give morphine. The goal was to understand if racial bias plays a role in pain manage…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Heart attack survivors get a buddy: new program aims to keep them moving
Knowledge-focused CompletedAfter a heart attack, cardiac rehab helps patients get active, but many stop exercising within a year. This completed trial tested a program where a 'patient partner' (a fellow heart patient) and a healthcare professional provided support through two teleconsultation sessions ove…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Can better training for anesthesia teams save lives after surgery?
Knowledge-focused CompletedThis study tested whether training healthcare teams to use special monitoring tools during general anesthesia could reduce complications and deaths after non-cardiac surgery. Over 1,000 patients were included, and the training focused on tools that track pain, brain activity, and…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Blood thinner dilemma: study seeks best timing for hip fracture surgery in seniors
Knowledge-focused CompletedThis study reviewed records of 610 older adults (over 65) on blood thinners who had hip fracture surgery. Researchers wanted to see how long surgery was delayed to avoid bleeding risks and whether that delay affected survival. The goal is to find the safest approach to schedule s…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Speedy bug ID: new tests aim to cut antibiotic guesswork in ICU blood infections
Knowledge-focused CompletedThis study tested whether three new diagnostic tools could help doctors pick the best antibiotic faster for ICU patients with Gram-negative bloodstream infections. Researchers compared standard lab methods to the new tests in 100 patients. The goal was to see if more patients got…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Scientists track bacteria shifts in Women's surgery recovery
Knowledge-focused CompletedThis study looked at how the bacteria in the vagina, urine, and gut change before and after vaginal surgery in 60 menopausal women. Researchers took swabs before surgery and at 6 weeks and 12 months after to see if different bacteria types are linked to symptoms. The goal was to …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Pregnancy cell study: could tiny processes predict complications?
Knowledge-focused CompletedThis study looked at two natural cell processes—autophagy (cell cleaning) and apoptosis (cell death)—in 97 pregnant women. Researchers wanted to see how these processes vary in normal pregnancies and in women at risk for complications. The goal was to understand the balance betwe…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Tight stockings under the microscope: new data on vein pressure
Knowledge-focused CompletedThis study looked at how compression stockings of different strengths change the size and pressure of leg veins in people with chronic venous insufficiency and healthy volunteers. Researchers measured vein diameter and leg pressure while participants stood, sat, or lay down. The …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Can a tablet replace the nurse visit? new device tested at home
Knowledge-focused CompletedThis study tested a device called SMART ANGEL that lets patients record their blood pressure, heart rate, and oxygen levels at home after outpatient surgery. 30 adults used the device to send their health data to doctors. The goal was to see if the device is easy to use and works…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Heart map may predict ablation success for AFib patients
Knowledge-focused CompletedThis study looked at 175 adults with atrial fibrillation who had radiofrequency ablation. Researchers wanted to see if a special map of the heart's electrical signals (called an isochron map) could predict whether patients would stay free of atrial fibrillation 18 months later. T…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Can a video call replace your Pre-Surgery anesthesia visit?
Knowledge-focused CompletedThis study looked at whether a video call (telemedicine) is as good as an in-person visit for checking a patient's health before surgery. 172 adults scheduled for surgery at a French hospital took part. Researchers compared how well each method captured important details like med…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Researchers compare three methods to measure pelvic extension in healthy volunteers
Knowledge-focused CompletedThis study looked at 120 healthy volunteers to see how well three different methods (in-person exam, photos, and a special X-ray system called EOS) measure pelvic extension. The goal was to describe pelvic movement patterns for four common body types. No treatment or intervention…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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ICU breathing tubes linked to brain fog months later?
Knowledge-focused CompletedThis study looks at 125 patients who were in the ICU, on a breathing machine and sedated for at least 48 hours. Researchers want to see how many have trouble with thinking or memory four months after leaving the hospital. Patients will talk to a psychologist before leaving the IC…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Why stroke patients avoid using their weak arm: new study investigates
Knowledge-focused CompletedAfter a stroke, many people can move their affected arm but choose not to, a condition called non-use. This study tested 53 participants (stroke survivors and healthy controls) to see how the need for force or precision affects arm use. Researchers used a weight-support system to…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Tiny study aims to perfect timing of electrical stimulation for stroke survivors
Knowledge-focused CompletedThis study observed 20 stroke patients with hemiplegia (weakness on one side) as they walked 10 meters. Researchers used sensors and a special walkway to measure foot movements and timing. The goal was to gather data that could help improve when functional electrical stimulation …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Rapid tests reveal hidden infections in detention centers
Knowledge-focused CompletedThis study tested 350 detainees in Nîmes, France for HIV, hepatitis B, and hepatitis C using rapid diagnostic tests. Many detainees come from areas where these infections are common and often don't know their status. The goal was to find out how many are infected so that care can…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Patient symptom surveys could cut chemo drug waste
Knowledge-focused CompletedThis study tested whether a 34-question symptom survey filled out by patients could give doctors enough information to authorize chemotherapy preparation, potentially reducing the number of unused drug doses. 138 people with digestive cancer participated. The goal was to see if t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Brain scan study aims to predict glioblastoma drug response
Knowledge-focused CompletedThis completed pilot study tested whether two types of brain scans—FDG PET and CT perfusion—can predict how well the drug bevacizumab works in people with recurrent glioblastoma, an aggressive brain cancer. Fourteen patients were scanned before treatment and then classified as re…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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ER violence under the microscope: counting aggressive incidents in a french hospital
Knowledge-focused CompletedThis study aimed to count how often violent events happen in the emergency department of a French hospital. Researchers observed 30 patients and staff over work periods, tracking pre-defined aggressive behaviors. The goal was to better understand the frequency and patterns of vio…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Shock therapy: high norepinephrine doses linked to death risk
Knowledge-focused CompletedThis study looked at 100 ICU patients with circulatory shock who received norepinephrine, a drug that raises blood pressure. Researchers wanted to see if a certain dose was linked to higher death rates within 5 days. They also studied how long patients needed the drug and the tot…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Kids' antibiotic habits under the microscope: new study tracks compliance after hospital discharge
Knowledge-focused CompletedThis study looked at how well children under 16 take their anti-infective medicines after being discharged from the hospital. Researchers followed 75 kids for one month to see if they followed their prescription correctly. The goal is to understand current compliance rates and he…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Robot surgery vs. traditional: which prostate cancer treatment costs less?
Knowledge-focused CompletedThis study looked at the total cost of two types of prostate cancer surgery over 5 years: robot-assisted surgery using the da Vinci system and traditional open surgery. Researchers tracked medical expenses and patient outcomes in 90 men with localized prostate cancer. The goal wa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Vitamin D's hidden power: immune cell changes revealed in healthy volunteers
Knowledge-focused CompletedThis study looked at how high doses of vitamin D change immune cells in 56 healthy adults over 3 months. Researchers used advanced lab tests to measure different types of immune cells before and after treatment. The goal was to better understand vitamin D's effects on the immune …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Pandemic's hidden toll: study reveals PTSD and burnout in ICU staff
Knowledge-focused CompletedThis study looked at the psychological impact of the COVID-19 pandemic on healthcare workers in intensive care units. Over 700 doctors, nurses, and aides completed questionnaires about post-traumatic stress, anxiety, depression, and burnout. The goal was to measure how common the…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Immune cells linked to insulin resistance in new study
Knowledge-focused CompletedThis study looked at whether immune cells from healthy people can affect how the body responds to insulin. Researchers took blood samples from 30 volunteers and tested how their immune cells influenced insulin signaling in liver cells in the lab. The goal was to better understand…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Gut bugs may hold key to immunotherapy response in bladder cancer
Knowledge-focused CompletedThis completed pilot study looked at whether the proteins produced by gut bacteria differ between bladder cancer patients who respond to immunotherapy and those who do not. Researchers collected stool and blood samples from 40 patients with advanced bladder cancer. The goal was t…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Tiny muscle signals could predict botox success in stroke survivors
Knowledge-focused CompletedThis study looked at 40 stroke patients with arm muscle stiffness (spasticity) who were treated with botulinum toxin (Botox). Researchers measured tiny electrical signals in the muscle to see how they change over time and whether they relate to how well the treatment works. The g…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Small study probes bleeding danger in stroke patients with 'leaky' brain vessels
Knowledge-focused CompletedThis study looked at 15 stroke patients with a condition called cerebral amyloid angiopathy (CAA), which makes blood vessels in the brain fragile and prone to bleeding. All patients received a clot-busting drug (thrombolysis) and were checked for brain bleeding 24 hours later. Re…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New french tool aims to better understand how patients perceive their back pain
Knowledge-focused CompletedThis study tested a French version of the Fremantle Back Awareness Questionnaire (FreBAQ) in 150 people with chronic low back pain. The questionnaire measures how patients perceive their back, including neglect and body image. The goal was to confirm that the French version works…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Tiny study aims to unlock how blood filtering helps CIDP
Knowledge-focused CompletedThis study looked at two types of plasmapheresis (blood filtering) in 8 people with CIDP, a rare nerve disorder causing weakness. The goal was to see how each method affects immune cells in the blood. It is a very early, small study focused on understanding how these treatments w…
Phase: EARLY_PHASE1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Can less fluid be better for septic shock patients?
Knowledge-focused CompletedThis study tested whether carefully limiting fluids given for non-emergency reasons (like nutrition or drug dilution) could reduce fluid overload in intensive care patients with septic shock. 50 patients were randomly assigned to either the standard approach or a restrictive flui…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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How do antifungals behave in septic shock? small study aims to find out
Knowledge-focused CompletedThis completed Phase 4 study looked at how the body processes echinocandin antifungal drugs (caspofungin or micafungin) in 24 adults with septic shock caused by peritonitis. Researchers measured drug levels in the blood to understand clearance, distribution, and concentration. Th…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Can rehab get chronic back pain patients moving more and sitting less?
Knowledge-focused CompletedThis study looked at 89 adults with chronic low back pain who went through a rehabilitation program. Researchers measured their physical activity, sitting time, and motivation before and after the program. The goal was to see if the program helped patients become more active and …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Scientists probe immune overreaction in severe COVID-19
Knowledge-focused CompletedThis study examined the immune systems of 120 COVID-19 patients who had trouble breathing. Researchers measured many immune markers in the blood to see if an overactive immune response causes lung damage. They also compared these markers to healthy people and looked for patterns …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Antibiotic levels measured in lungs of sickest pneumonia patients
Knowledge-focused CompletedThis study looked at how the antibiotic ceftobiprole moves through the blood and lungs of 12 adults with severe pneumonia who were on breathing machines. Researchers gave a high dose continuously through a vein and took blood and lung fluid samples to measure drug levels. The goa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Blood clot patients checked for 'Sleeping' gene mutations
Knowledge-focused CompletedThis completed study examined stored DNA from 150 adults over 50 who had a history of venous thromboembolism (blood clots). Researchers looked for specific gene mutations linked to a condition called clonal hematopoiesis of indeterminate potential (CHIP). The goal was to see how …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Ultrasound could give doctors a new window into lung health
Knowledge-focused CompletedThis study measured lung strain using ultrasound in 30 healthy adults, both while breathing normally and while on a breathing machine. The goal was to establish normal values and see how lung strain changes with different breathing volumes. This could lead to a new bedside tool t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Blood marker may predict COVID-19 survival
Knowledge-focused CompletedThis study examined whether a blood test parameter called NEU-SFL, which reflects neutrophil activation, could predict the risk of death in patients hospitalized for COVID-19 in 2021. Researchers compared NEU-SFL levels between those who survived and those who died. The goal was …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Which screening test is better for spotting brain fog in alcohol use disorder?
Knowledge-focused CompletedThis study compared two simple questionnaires—the MoCA and the BEARNI—to see which one better detects cognitive problems in people with alcohol use disorder. Researchers tested 90 patients and compared the results against a full set of standard neuropsychological tests. The goal …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Throat bone may play role in stroke: new study explores link
Knowledge-focused CompletedThis study looked at 206 patients who had carotid artery surgery to see if the hyoid bone (a small bone in the neck) is linked to artery narrowing and stroke. Researchers used CT scans to measure the distance and position between the hyoid bone and the carotid artery. The goal wa…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Tiny study probes how COVID shots alter immune cell activity
Knowledge-focused CompletedThis completed early-phase study looked at how mRNA COVID-19 vaccines (Pfizer or Moderna) affect certain immune cells called monocytes in people of different ages. Researchers measured changes in reactive oxygen species (a type of cell activity) and a blood protein called AngII b…
Phase: EARLY_PHASE1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Gene hunt: why does sunitinib work differently in kidney cancer patients?
Knowledge-focused CompletedThis completed study enrolled 43 people with kidney cancer who were starting sunitinib (Sutent). Researchers measured the drug's level in the blood and checked for genetic differences that might affect how the body processes it. The goal was to understand why sunitinib levels var…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Can CRPS patients imagine movement? new study investigates
Knowledge-focused CompletedThis completed study compared how well people with complex regional pain syndrome (CRPS), people with other muscle or bone pain, and healthy individuals can imagine movements. Researchers used a questionnaire called the MIQ-RS to measure motor imagery skills. The goal was to see …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Pocket ultrasound could give quick, reliable heart checks in the ER
Knowledge-focused CompletedThis study tested a new automatic tool on a pocket ultrasound device to measure how well the heart pumps blood (left ventricle ejection fraction). Researchers compared its results to those from heart MRI, the gold standard, in 60 adults with shortness of breath, low blood pressur…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Scientists uncover immune clues in pregnancy complication
Knowledge-focused CompletedThis study looked at how certain immune cells (neutrophils) form web-like structures in women with preeclampsia compared to those with normal pregnancies. Researchers analyzed stored blood samples from 26 women to understand two different ways these webs are made. The goal was to…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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ICU antibiotic dosing: what really matters?
Knowledge-focused CompletedThis study looked at 156 critically ill patients to find out what factors help achieve the right levels of beta-lactam antibiotics in the blood. Researchers collected clinical data and used therapeutic drug monitoring to see which patients reached target concentrations. The goal …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Tiny brain strokes linked to heart hole in young adults
Knowledge-focused CompletedThis study looked at 50 young adults (under 60) who had a stroke with no clear cause. Researchers wanted to see if small strokes in the cerebellum (back part of the brain) were linked to a common heart condition called PFO (a small hole between the heart's upper chambers). They c…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Pharmacist intervention may boost pneumococcal shots in hospital patients
Knowledge-focused CompletedThis study looked at whether a clinical pharmacist could help increase pneumococcal vaccination rates in patients at high risk for infection when they leave the hospital. Researchers tracked how many vaccine prescriptions were given to 167 at-risk adults. The goal was to see if t…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Brain scan clues could help tell two blood vessel diseases apart
Knowledge-focused CompletedThis study looked at brain scans from 315 people with two types of small vessel disease: cerebral amyloid angiopathy (CAA) and hypertensive arteriopathy (HA). Researchers wanted to see if the pattern of white matter changes around the brain's fluid-filled spaces could help tell t…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Nursing home staff under siege: study reveals high rates of PTSD during pandemic
Knowledge-focused CompletedThis study looked at how the COVID-19 pandemic impacted the mental health of 501 nursing home workers in Occitanie, France. Researchers measured rates of post-traumatic stress disorder (PTSD), depression, and burnout using standard questionnaires. The goal was to understand how c…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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France's ICU expansion during COVID: a look back at how hospitals coped
Knowledge-focused CompletedThis study looked back at how French hospitals created more intensive care unit (ICU) beds and found extra healthcare workers during the COVID-19 pandemic. Researchers gathered information from nearly 10,000 hospitals across France. The goal was to understand where the new beds c…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Magnetic needle guide tested on dummies for safer IV insertion
Knowledge-focused CompletedThis study tested a new magnetic device (Needle-Pilot) to help doctors insert central venous catheters into a practice mannequin. 51 doctors from a French hospital participated. The goal was to see if the device made the procedure faster or easier compared to standard ultrasound …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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French hospitals review gunshot wound care in ICUs
Knowledge-focused CompletedThis study looked back at records of 120 people admitted to intensive care units in four French hospitals after gunshot wounds. The goal was to describe how often patients died within 28 days and what factors might affect their survival. The study did not test any new treatment, …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Blood protein clues may predict dangerous pregnancy problems
Knowledge-focused CompletedThis study measured certain proteins (histones and HMGB1) in the blood of 115 pregnant women to see if they could help detect placenta-related complications like pre-eclampsia. Researchers compared women with normal pregnancies, those with complications, and healthy non-pregnant …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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French ICUs treat more sick patients, but deaths drop
Knowledge-focused CompletedThis study looked at over 1.5 million adults admitted to French intensive care units (ICUs) between 2013 and 2019. Researchers found that while patients were becoming more critically ill, their stays in the ICU got shorter and death rates decreased. The goal was to understand tre…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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MRI study sheds light on hidden brain bleeding patterns
Knowledge-focused CompletedThis study looked at 111 people with cerebral amyloid angiopathy (CAA), a condition that causes bleeding in the brain. Researchers used MRI scans to check for iron deposits in the cerebellum, a part of the brain that controls balance and coordination. The goal was to learn where …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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COVID-19 blood clot mystery: new study aims to unravel why some patients develop dangerous clots
Knowledge-focused CompletedThis completed study looked at blood clotting in 175 hospitalized COVID-19 patients. Researchers used a special test to measure how quickly and strongly blood clots form, and whether a protein called thrombomodulin can slow this process. The goal was to understand why some COVID-…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Heart clots leave unique brain marks after stroke
Knowledge-focused CompletedThis study looked at brain MRI scans of 122 stroke patients to see if those with a blood clot in the heart (intracardiac thrombus) had different patterns of brain damage compared to those with atrial fibrillation. Researchers analyzed the location, size, and number of stroke lesi…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Pre-Surgery blood vessel block may boost colon healing
Knowledge-focused CompletedThis small pilot study tested whether blocking the inferior mesenteric artery with tiny particles 3-4 weeks before rectal or sigmoid colon cancer surgery helps the colon develop extra blood vessels. The goal was to see if this improves blood flow and oxygen supply to the colon du…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Scientists measure walking imbalance in amputees
Knowledge-focused CompletedThis study looked at how people with leg amputations (below or above the knee) balance while walking. Researchers used special pressure-sensing platforms to measure the center of pressure in 130 patients after they finished rehabilitation. The goal was to understand walking asymm…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Hidden danger: abuse may double blood clot risk for women on the pill
Knowledge-focused CompletedThis completed study looked at whether intimate partner violence (IPV) increases the risk of blood clots in women taking combined oral contraceptives. Researchers compared 997 women who had a first blood clot with similar women who did not, using a questionnaire to screen for IPV…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Protein test may spot preeclampsia risk in High-Risk pregnancies
Knowledge-focused CompletedThis study examined whether measuring a protein called ADAMTS13 in early pregnancy can help predict preeclampsia in women with antiphospholipid antibody syndrome (APS). Researchers analyzed stored blood samples from 513 women in the NOH-APS cohort who became pregnant after their …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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What happens to the sickest COVID patients? french ICU study aims to find out
Knowledge-focused CompletedThis study followed over 1,000 adults with confirmed or suspected COVID-19 who were admitted to intensive care units (ICUs) across France. Researchers tracked their treatments, complications, and survival at 28 days. The goal was to learn how these patients are managed and what f…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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New heart ultrasound tool tested in ICU: could it save time?
Knowledge-focused CompletedThis study tested a new automatic way to measure heart function using ultrasound in 70 ICU patients with acute circulatory failure (shock). The automatic method was compared to the standard manual approach to see if they agree. If the automatic method works well, it could help do…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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New therapies for Women's pelvic pain under the microscope
Knowledge-focused CompletedThis study looked at 173 women with pelvic or perineal issues (like pain, incontinence, or scarring) that didn't get better with standard treatments. Researchers observed the use of newer therapies such as LED light, radiofrequency, laser, and hyaluronic acid injections. The goal…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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DNA levels in blood tracked during cancer operations
Knowledge-focused CompletedThis study looked at how DNA from tumors changes in the blood before, during, and after surgery for breast, prostate, or colon cancer. Thirty adults having curative surgery provided blood samples to measure these DNA levels. The goal was to understand the natural pattern of DNA c…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Spinal fluid clues may predict MS years before symptoms
Knowledge-focused CompletedThis study examined 100 people who had brain MRI findings suggesting possible multiple sclerosis (MS) but no symptoms yet. Researchers measured four new biomarkers in their spinal fluid and blood to see if these could predict who would later develop MS. The goal was to improve ea…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Could pregnancy loss signal future cancer risk? new study investigates
Knowledge-focused CompletedThis study followed over 1,500 women who had pregnancy losses and were tested for antiphospholipid syndrome (APS) and other clotting disorders. Researchers compared cancer rates among women with APS, those with other clotting gene changes, and those with no clotting issues. The g…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Blood protein may help ER spot serious headaches
Knowledge-focused CompletedThis study looked at whether measuring a protein called S100B in the blood can help emergency doctors tell the difference between primary headaches (like migraines) and secondary headaches (caused by something serious like a bleed or infection). Researchers enrolled 81 adults wit…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Could a common virus and low vitamin d trigger MS? new study investigates
Knowledge-focused CompletedThis completed study examined 110 people with radiologically isolated syndrome (RIS) — a condition where brain scans show signs that could lead to multiple sclerosis (MS). Researchers looked at whether past Epstein-Barr virus infection and low vitamin D levels are linked to a hig…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Hidden diabetes complication under the microscope: charcot foot care revealed
Knowledge-focused CompletedThis study aimed to learn how Charcot foot, a serious but poorly understood diabetes complication, is currently diagnosed and treated in specialized foot centers across France and Belgium. Researchers collected information from over 1,100 patients to identify common practices and…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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New study looks at early treatment of abdominal infections
Knowledge-focused CompletedThis study observed 200 adults who came to the emergency room with a suspected abdominal infection that needed surgery. Researchers wanted to see how quickly patients received antibiotics and surgery, and how that affected their hospital stay. The goal was to find factors that le…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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New questionnaire aims to predict falls in the elderly
Knowledge-focused CompletedThis study tested a questionnaire called the Balance and Daily Life (EVQ) to see if it reliably measures balance and fall risk in frail elderly people. Researchers enrolled 140 participants aged 65 and older who were hospitalized for physical medicine. The goal was to check if th…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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New heart imaging study seeks clues in septic shock survival
Knowledge-focused CompletedThis study looked at 50 adults with septic shock to see how a sensitive heart ultrasound technique, called strain echocardiography, can track heart function changes. The goal was to understand if these measurements can help predict patient outcomes. The research did not test a tr…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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New blood pressure test could help kidney patients
Knowledge-focused CompletedThis study tested a new way to measure blood pressure in 90 people with severe kidney disease. The new method uses a different part of the blood pressure wave, and researchers wanted to see if it works as well as the standard arm cuff method. The goal was to find a more accurate …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Study tests whether a standard Clot-Risk tool works for hospital patients on blood thinners
Knowledge-focused CompletedThis study looked at how well the Wells score, a tool used to predict deep vein thrombosis (blood clots), works for hospitalized patients who are already receiving blood thinners. Researchers compared the score's accuracy between patients with and without thromboprophylaxis and c…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Gut bacteria clues in new arthritis patients
Knowledge-focused CompletedThis study looked at the gut bacteria of 55 people—some newly diagnosed with rheumatoid arthritis and some without the disease. Researchers wanted to see if certain bacteria are more common in arthritis patients. The goal is to better understand how gut health might be linked to …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Simple blood test after heparin could spot High-Risk pregnancies
Knowledge-focused CompletedThis study followed 513 women with antiphospholipid syndrome starting a new pregnancy. Researchers measured two blood markers (PGF and sFlt1) before and after the first low-molecular-weight heparin injections. The goal was to see if changes in these markers could predict serious …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Immune clues could predict diabetes risk in older adults
Knowledge-focused CompletedThis study examined blood samples and physical measurements from 158 adults aged 55-69 to see if certain immune system patterns are linked to insulin resistance, a condition that can lead to diabetes. Researchers measured various immune cells and markers to find a profile that co…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Global survey reveals how ICUs use powerful antibiotics
Knowledge-focused CompletedThis completed study surveyed 964 intensive care patients across multiple countries to understand how doctors currently prescribe and monitor aminoglycoside antibiotics (tobramycin, amikacin, gentamicin). Researchers collected data on dosing, therapy duration, and drug monitoring…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Robot help for Surgeons-in-Training: does it speed up learning?
Knowledge-focused CompletedThis study tested whether surgical interns learn faster with robotic assistance during laparoscopic training. 34 interns were split into two groups: one trained with a standard pelvic trainer, the other with robotic help. They were then timed while performing a kidney surgery on …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Brain scans may predict recovery in conversion disorder
Knowledge-focused CompletedThis study looked at 20 people with a first episode of motor conversion disorder, a condition where psychological stress causes physical symptoms like paralysis. Researchers used PET scans to measure brain metabolism at the start of symptoms and checked if those patterns related …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Can distraction change how you walk with back pain?
Knowledge-focused CompletedThis pilot study looked at how distraction (like listening to something) changes walking patterns and pain in people with chronic low back pain. Sixteen participants walked on a treadmill at different speeds, with and without distraction. The goal was to see if distraction could …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Ultrasound-Guided vein access: which route is safer?
Knowledge-focused CompletedThis study compared two ultrasound-guided methods for inserting a central venous catheter: one through the lower part of the internal jugular vein and the other through the subclavian vein. Researchers wanted to see which approach is more successful and safer. The study involved …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Mental health risks explored in women with pregnancy loss condition
Knowledge-focused CompletedThis study looked at how common major psychiatric disorders are in women with antiphospholipid syndrome (a blood clotting disorder) and similar pregnancy loss histories. Researchers compared three groups of women about 10 years after their initial diagnosis. The goal was to under…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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ALS gene hunt: vitamin d clues under microscope
Knowledge-focused CompletedThis completed study looked at genetic differences in vitamin D processing and action in 400 people with ALS and 400 healthy controls. Researchers analyzed DNA samples to find variations in eight specific genes. The goal was to better understand the biology of ALS, not to test a …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Blood DNA levels may signal pregnancy problems
Knowledge-focused CompletedThis study measured the amount of free-floating DNA and nucleosomes in the blood of 137 women to see if these levels differ between those with pregnancy complications (like preeclampsia or blood clots) and healthy women (both pregnant and non-pregnant). The goal was to better und…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Breathing tube removal method may boost oxygen after surgery
Knowledge-focused CompletedThis study tested two methods of removing a breathing tube after general anesthesia to see which helps patients breathe room air longer without their oxygen levels dropping. 68 adults having limb surgery took part. The goal was to find a safer way to wake up from anesthesia.
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Healthy volunteers help doctors understand vein collapse
Knowledge-focused CompletedThis study looked at how the inferior vena cava, a large vein returning blood to the heart, changes size with breathing in 52 healthy volunteers. Researchers used ultrasound to measure the vein's diameter and diaphragm movement during controlled breaths. The goal was to find a br…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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ICU dialysis study seeks sweet spot for fluid removal
Knowledge-focused CompletedThis study looked at 39 intensive care patients with acute kidney failure who needed dialysis to remove excess fluid. Researchers tested three different fluid removal rates (1, 2, and 3 ml per kg per hour) to see which caused the fewest drops in blood pressure while still effecti…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Sitting study reveals how chairs change your spine
Knowledge-focused CompletedThis study looked at how sitting in a regular chair versus an ergonomic chair changes the curve of your lower back and pelvis. Researchers measured 20 people, some with chronic back pain and some without, to see if chair type makes a difference. The goal was to understand how sit…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Social hardship linked to late breast cancer detection
Knowledge-focused CompletedThis study looked at whether people with unstable living conditions are more likely to be diagnosed with advanced breast cancer. Researchers compared 684 patients with early-stage versus late-stage breast cancer. They found that social fragility may be linked to a later diagnosis…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Finger-Prick blood test may rival standard lab draw for elderly on warfarin
Knowledge-focused CompletedThis study looked at 31 elderly nursing home residents taking blood thinners (vitamin K antagonists) to see if a simple finger-prick test (capillary INR) gives the same results as a standard blood draw (venous INR) for making treatment decisions. Over 6 months, researchers compar…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Scientists probe colon Cancer's 'Root' cells to unlock new treatments
Knowledge-focused CompletedThis completed study looked at 60 people with colorectal cancer to better understand the cells that help the cancer spread and resist chemotherapy. Researchers collected blood and tumor samples to identify and study these 'cancer stem cells' in the lab. The goal was to learn more…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Blood test for clot risk? study checks monthly changes
Knowledge-focused CompletedThis study looked at whether levels of nucleosomes and free DNA in the blood change from month to month in healthy people and in those who have had a blood clot (venous thromboembolism). Researchers measured these markers monthly for six months in 15 healthy volunteers and 15 pat…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Tailored workouts may boost heart function in obesity and diabetes
Knowledge-focused CompletedThis study tested whether an 8-week individualized training program could improve heart and blood vessel function in men with obesity or type 2 diabetes. Researchers compared four groups: trained and untrained healthy volunteers, obese subjects, and diabetic patients. The goal wa…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Healthy volunteers help unravel movement mysteries
Knowledge-focused CompletedThis study looked at how complex our movements are by measuring finger-tapping patterns in 60 healthy volunteers. The goal was to understand normal sensorimotor behavior and see if these measurements could be useful in future clinical settings. No treatment was given; it was pure…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Do kidney disease or diabetes change how long nerve blocks last?
Knowledge-focused CompletedThis completed study looked at how long nerve blocks last in people with kidney failure or diabetes compared to those without these conditions. Researchers gave 120 patients a truncal block during hand or wrist surgery and measured when sensation returned. The goal was to see if …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New sexuality questionnaires tested for women with bladder or pelvic issues
Knowledge-focused CompletedThis study tested two French questionnaires about sexuality in 298 women who had surgery for urinary incontinence, pelvic organ prolapse, or fecal incontinence. The goal was to see if these questionnaires accurately measure sexual function compared to an existing tool. No treatme…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Ultrasound may take the guesswork out of wrist blood draws
Knowledge-focused CompletedThis study tested whether using an ultrasound device to locate the radial artery in the wrist helps healthcare workers draw blood on the first try. 74 adults who needed an arterial blood sample took part. Half had the procedure with ultrasound guidance, half without. Researchers …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Back pain study reveals hidden instability in everyday movements
Knowledge-focused CompletedThis study looked at how chronic low back pain changes the way people control their movements. Researchers compared 70 participants—some with long-term back pain and some healthy—by measuring their stability during bending and twisting motions. The goal was to better understand t…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New blood score could predict septic shock survival
Knowledge-focused CompletedThis study tested a new scoring system that uses routine blood tests to predict the risk of death within one month for patients in intensive care with septic shock. Researchers looked at 780 patients to see how well the score works. The goal is to help doctors make faster, better…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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French hospitals track spleen injury care to find best practices
Knowledge-focused CompletedThis study looked at how 93 people with spleen injuries from accidents were treated in hospitals in southern France. Researchers tracked deaths, complications, and how long patients stayed in the hospital. The goal was to understand current treatment patterns and outcomes, not to…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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ICU antibiotic levels under the microscope
Knowledge-focused CompletedThis study looked at whether antibiotics given to critically ill patients reach high enough levels in the blood to kill bacteria. Researchers measured drug concentrations in 98 ICU patients and compared them to targets known to be effective. The goal was to understand dosing, not…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Vaginal bacteria linked to birth tears?
Knowledge-focused CompletedThis study looked at 1,100 pregnant women to see if having abnormal vaginal bacteria (like bacterial vaginosis) makes vaginal tears more likely during delivery. Researchers checked routine vaginal test results and recorded any tears that happened. The goal is to understand if thi…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Thirst-Guided hydration studied in Ultra-Trail runners
Knowledge-focused CompletedThis study followed 198 runners in the 2015 Ultra-Trail Mont-Blanc to see if drinking only when thirsty ("at thirst") keeps blood sodium levels more stable compared to other drinking plans. The goal is to understand how hydration affects health during extreme endurance events. Re…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Brain scans reveal how stroke survivors recover movement
Knowledge-focused CompletedThis study used a special light-based imaging technique called fNIRS to watch how the brain reorganizes itself in the first two months after a stroke. Ten participants who had a stroke 2-4 weeks earlier underwent standard physical and occupational therapy while researchers measur…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Ultrasound showdown: which vein route wins for catheter placement?
Knowledge-focused CompletedThis study looked at 132 people who needed a central venous catheter (a thin tube placed in a large vein). Doctors compared two ultrasound-guided methods: one using the subclavian vein (under the collarbone) and one using the axillary vein (in the armpit). The goal was to see whi…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Ultrasound beats touch for tough blood draws?
Knowledge-focused CompletedThis study tested whether using ultrasound to find the wrist artery makes blood draws easier for patients whose arteries are hard to feel. 74 adults with difficult-to-locate arteries were randomly assigned to have their blood drawn with or without ultrasound guidance. The main go…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Post-Birth sugar check reveals hidden diabetes risk in moms
Knowledge-focused CompletedThis study looked at 500 women who had gestational diabetes during pregnancy. They took a glucose test 4 to 12 weeks after giving birth to see how many had type 2 diabetes, impaired glucose tolerance, or impaired fasting glucose. The goal was to compare women diagnosed with gesta…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New study aims to catch deadly fungal infections earlier in ICUs
Knowledge-focused CompletedThis study looked at better ways to detect Candida (a type of fungus) infections early in intensive care unit (ICU) patients. Researchers tested 422 non-neutropenic adults who had been in the ICU for more than 48 hours. They used four different tests, including blood tests and sw…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Robots take on throat cancer: early results show promise
Knowledge-focused CompletedThis study looked at how well robot-assisted surgery removes early-stage laryngeal cancer. 54 patients had their tumors removed using a da Vinci robot. The main goal was to see how often the surgery got all the cancer out (clear surgical margins). The study also tracked surgery t…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Blood test showdown: which method spots melanoma cells better?
Knowledge-focused CompletedThis study compared two blood test methods, EPISPOT and CellSearch, to see how well they detect circulating melanoma cells in people with advanced melanoma. Researchers took blood samples from 73 participants, including patients with stage 4 melanoma and hospitalized controls wit…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Arm position matters for vein visibility on ultrasound
Knowledge-focused CompletedThis study looked at 50 healthy adults to see if changing arm position makes veins in the armpit and collarbone area show up bigger on ultrasound. The goal was to find the best arm position for easier and safer vein access. Results help guide doctors when placing central lines.
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Twin birth study: vaginal vs. C-Section and incontinence risk
Knowledge-focused CompletedThis study looked at over 3,000 first-time mothers of twins to see if the way they gave birth (vaginal or cesarean) affected their risk of leaking urine 3 months after delivery. The goal was to understand which delivery method might be safer for bladder health. The study did not …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Can two doctors get the same ultrasound reading? small study tests reliability in breathing emergencies
Knowledge-focused CompletedThis study looked at whether two different doctors can get the same diaphragm measurements using ultrasound in patients with severe breathing problems in the emergency room. 26 adults with acute respiratory distress were each scanned twice by two separate investigators. The goal …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Bone scanner showdown: are new machines as accurate as the old?
Knowledge-focused CompletedThis study tested two different bone densitometers (the Stratos DR and the Discovery A) to see if they give the same results when measuring body fat and lean muscle mass. Fifty adults who were already scheduled for a bone density scan took part. Each person was scanned on both ma…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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New sensor aims to help stroke survivors walk better
Knowledge-focused CompletedThis study tested a small, wearable sensor (FOX HiKoB) to measure foot movement in 29 stroke survivors who have foot drop. The goal was to see if the sensor could accurately detect when the foot lifts, which could then trigger electrical stimulation to help lift the foot. The sen…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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New study tests if simple guidelines can cut unnecessary ER scans
Knowledge-focused CompletedThis study looked at whether giving emergency room doctors referral guidelines helps them order more relevant imaging exams. Over 8,500 patients were observed before and after the guidelines were introduced. The goal was to see if the rate of confirmed diagnoses improved, meaning…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Fasting before surgery: safe or risky? new study checks blood volume
Knowledge-focused CompletedThis study looked at whether not eating before surgery (preoperative fasting) causes low blood volume. Researchers used heart ultrasound to measure blood volume changes in 100 patients before and after fasting. The goal was to see if fasting increases the chance of low blood volu…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Scientists hunt for biological clues in mysterious movement disorder
Knowledge-focused CompletedThis study examined 20 adults experiencing their first episode of conversion disorder (a condition where psychological stress causes physical symptoms like paralysis or abnormal movements). Researchers measured inflammation markers in the blood and compared them with brain scans …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Immune cell study sheds light on childhood disease
Knowledge-focused CompletedThis study examined blood samples from 100 children with Henoch Schönlein Purpura (HSP) and a control group to see if regulatory T cells (Tregs) are missing or not working properly. The goal was to learn more about the disease, not to test a new treatment. Researchers measured Tr…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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New tool aims to predict kidney disease risk after severe injury
Knowledge-focused CompletedThis study looked at 319 patients who needed dialysis for severe acute kidney injury. Researchers collected their medical information to identify risk factors for developing chronic kidney disease. The goal was to create a scoring system that helps doctors decide which patients w…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Timing is everything: fluid challenge evaluation in septic shock
Knowledge-focused CompletedThis study looked at 145 patients with septic shock to see if the time when doctors check if a fluid bolus worked changes the results. Patients received 500 ml of fluid over 10 minutes. The study found that some patients who seemed to respond right away were no longer responding …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Can your first week of pain after surgery predict chronic pain?
Knowledge-focused CompletedThis study followed 392 adults who had planned surgeries to map their pain levels over the first 7 days after the operation. Researchers wanted to see if certain pain patterns could predict who would still have pain 3 months later. The goal is to better understand and possibly pr…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Nose bacteria linked to diabetic foot infections?
Knowledge-focused CompletedThis study looked at 278 diabetic patients to see if the same staph bacteria found in their noses also appear in their foot ulcers. Researchers compared the genetic fingerprints of the bacteria to understand the link. The goal was to learn more about infection risks, not to test …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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New CT method could slash radiation in bone scans
Knowledge-focused CompletedThis study tested whether a newer CT reconstruction method (ASIR) can produce bone SPECT-CT images as good as the standard method (FBP) while using less radiation. Researchers enrolled 75 patients scheduled for a SPECT-CT exam. They compared image quality by measuring signal and …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Which mattress wins? study tests pressure relief for bedridden patients
Knowledge-focused CompletedThis study compared two special mattresses designed to prevent bedsores in people who are bedridden. Researchers measured pressure on the body while patients lay on each mattress. The goal was to see which mattress spreads pressure more evenly, which could help reduce the risk of…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC