Centre Hospitalier Universitaire De Nīmes

This study follows 100 men who have had prostate surgery and still struggle with stress urinary incontinence (leaking urine when coughing or moving). They receive an adjustable implant called REMEEX to help control leakage. Researchers will track how well it works, side effects, …

This study looks at how well a combination of two drugs (enfortumab vedotin and pembrolizumab) works as a first treatment for people with advanced upper tract urothelial carcinoma, a rare cancer of the urinary tract. Researchers will track 50 patients in France to see how many re…

This study tests whether a newer type of blood thinner (DOA) works better than the standard one (VKA) for dissolving dangerous blood clots inside the heart. About 340 adults with such clots will be randomly assigned to one of the two treatments. The goal is to see which drug redu…

This study looks at whether involving bipolar patients in decisions about their long-term medication (shared decision-making) helps them take their medicine as prescribed. Researchers will compare standard care to a shared decision-making plan in 300 adults after a mood episode. …

This study aims to see if a simple, inexpensive saliva test can accurately diagnose Cushing's syndrome, a condition where the body makes too much cortisol. Researchers will compare two automated saliva test methods in 380 adults who are already being checked for the condition. Th…

This trial tests whether a continuous infusion of numbing and anti-inflammatory drugs directly into the C-section wound can control pain as well as a standard spinal injection of morphine. The study enrolls women having a planned C-section with a single, healthy pregnancy. Resear…

This study planned to see if having a dietitian help follow nutrition guidelines improves calorie intake for ICU patients. It was withdrawn before enrolling anyone, so no results are available. The goal was to measure energy balance over seven days.

This study was designed to compare decision-making skills between bipolar patients who had attempted suicide and those who had not. Researchers planned to use computer tasks and questionnaires to measure thinking patterns. However, the study was withdrawn before enrolling any par…

This study was designed to see how accurately patients report their own medication and healthcare use in diaries compared to official health insurance records. It planned to include people with diabetes, arthritis, kidney disease, or prostate cancer. However, the study was withdr…

This study tests whether a simple breathing test can reliably measure blood flow in the lining of the windpipe and large airways. Healthy adults breathe a harmless gas called dimethyl ether, and the amount they breathe out reveals how much blood is flowing through the airway tiss…

This study was designed to compare two procedures—vertebroplasty and kyphoplasty—for treating spinal fractures caused by trauma. Researchers planned to measure how much bone cement was injected and how well the spine's shape and function were restored. However, the study was with…

This study looks at data from 9,600 adults in France who had a special type of CT scan called spectral CT. The goal is to find safe radiation dose levels for these scans, which are not yet regulated. By analyzing past scans, researchers hope to create guidelines that protect pati…

This study looks at how the types of bacteria in the guts of premature babies during their first six weeks of life might affect their immune system at age 3. Researchers will track 130 preterm infants born before 33 weeks to see if early gut changes are linked to a balanced immun…

This study involves 48 adults with HIV who have had undetectable virus levels for at least 2 years while on antiretroviral therapy. Researchers are measuring two specific markers (CD32a and X) on immune cells to see if they relate to the amount of hidden HIV DNA in the body. The …

This study looks at how the process of diagnosing infertility affects the sexuality of couples. Researchers will survey 80 heterosexual couples to see if the diagnosis and testing cause sexual problems. The goal is to better understand the link between infertility and sexual heal…

This study uses a survey to understand why transgender men (people assigned female at birth who identify as male) in France may not get screened for cervical cancer. Researchers will ask 300 participants aged 25–65 about their screening history and what helps or hinders them. The…

This study looks at whether changes in gut bacteria can affect Sjögren's syndrome, an autoimmune disease causing dry eyes, dry mouth, and fatigue. Researchers will measure blood markers of gut leakage in 50 adults with Sjögren's to see if these markers change when disease activit…

This study looks at how COVID-19 changes the bacteria in the gut of hospitalized patients. Researchers will collect stool samples from 15 patients to measure the virus in feces and see if these changes relate to how sick patients become. The goal is to better understand the link …

This study looks at a type of bacteria called Staphylococcus pettenkoferi, often found in diabetic foot ulcers. Researchers will analyze the DNA of 230 bacterial samples to see if certain strains are more harmful. The goal is to understand if this bacteria plays a role in making …

This study uses ultrasound to measure heart changes in 66 healthy blood donors before and after giving blood. The goal is to see if a simple, non-invasive test can detect mild blood loss. If it works, it could help doctors spot internal bleeding early in trauma patients.