Robotic knee surgery debate: to keep or remove a key ligament?

NCT ID NCT07489963

Symptom relief Sponsor: Centre Hospitalier Universitaire de Nīmes Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether keeping or removing the posterior cruciate ligament during robotic knee replacement helps patients feel more natural after surgery. About 300 adults having their first robotic knee replacement will be randomly assigned to one of the two methods. The main goal is to see which group reports less awareness of their artificial knee one year later.

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Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Sep 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient scheduled for first-intention robotic-assisted total knee replacement (MAKO). * Unilateral replacement, regardless of laterality. * Patient able to answer questionnaires. * Patient willing to undergo usual 12-month follow-up. * Patient has given free and informed consent and has signed the consent form. * Patient affiliated with or benefiting from a health insurance scheme. Exclusion Criteria: * Patient with intraoperative technical impossibility of retaining PCL (flessum \> 20°, flexion stiffening \< 100°). * Previous posterior cruciate ligament surgery. * Post-traumatic gonarthrosis. * Valgus \> 185°. * Patient with septic complication. * Patient participating in another interventional trial. * Patient in an exclusion period determined by another study. * Patient under court protection, guardianship or curatorship. * Patient unable to give consent. * Patients for whom it is impossible to provide informed information. * Pregnant women

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee arthroplasty, total

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

3 sites. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Robotic knee surgery debate: to keep or remove a key ligament?

What the study statuses mean