Ultrasound may predict which patients get poor pain relief from a common knee block

NCT ID NCT07730216

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 28, 2026 · Last updated Aug 13, 2026 · Updated 3 times

Summary

After knee replacement, a nerve block called the adductor canal block is often used to control pain while preserving leg strength. But it does not work equally well for everyone. This study will examine whether ultrasound measurements—such as tissue depth and nerve visibility—can predict which patients will need extra pain medication. The goal is to identify factors that lead to block failure and improve pain management after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
adductor canal block (a nerve block procedure)
What this could lead to
If ultrasound features reliably predict block failure, doctors could adjust the technique or choose alternative pain relief for certain patients, improving recovery after knee replacement.
What could go wrong
This is an observational study, not a test of a new treatment. It may find that ultrasound measures are not strong enough predictors to change practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 623 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Scheduled for elective primary unilateral total knee arthroplasty under spinal anesthesia

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years * Scheduled for elective primary unilateral total knee arthroplasty under spinal anesthesia * American Society of Anesthesiologists (ASA) physical status I-III Exclusion Criteria: * Daily opioid use or chronic pain syndrome * Diabetic or other clinically diagnosed peripheral neuropathy * Coagulopathy * Infection at the injection site * Known allergy or hypersensitivity to local anesthetics * Revision total knee arthroplasty * Conversion from spinal anesthesia to general anesthesia during surgery * General anesthesia as the planned anesthetic technique

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Arthroplasty, replacement, knee are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Konya City Hospital

    RECRUITING

    Konya, Konya, 42090, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.