Ultrasound may predict which patients get poor pain relief from a common knee block
NCT ID NCT07730216
First seen Jul 28, 2026 · Last updated Aug 13, 2026 · Updated 3 times
Summary
After knee replacement, a nerve block called the adductor canal block is often used to control pain while preserving leg strength. But it does not work equally well for everyone. This study will examine whether ultrasound measurements—such as tissue depth and nerve visibility—can predict which patients will need extra pain medication. The goal is to identify factors that lead to block failure and improve pain management after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- adductor canal block (a nerve block procedure)
- What this could lead to
- If ultrasound features reliably predict block failure, doctors could adjust the technique or choose alternative pain relief for certain patients, improving recovery after knee replacement.
- What could go wrong
- This is an observational study, not a test of a new treatment. It may find that ultrasound measures are not strong enough predictors to change practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 623 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2026
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Scheduled for elective primary unilateral total knee arthroplasty under spinal anesthesia
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years * Scheduled for elective primary unilateral total knee arthroplasty under spinal anesthesia * American Society of Anesthesiologists (ASA) physical status I-III Exclusion Criteria: * Daily opioid use or chronic pain syndrome * Diabetic or other clinically diagnosed peripheral neuropathy * Coagulopathy * Infection at the injection site * Known allergy or hypersensitivity to local anesthetics * Revision total knee arthroplasty * Conversion from spinal anesthesia to general anesthesia during surgery * General anesthesia as the planned anesthetic technique
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Konya City Hospital
RECRUITINGKonya, Konya, 42090, Turkey (Türkiye)
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