Dialysis showdown: which method cleans blood better in the ICU?

NCT ID NCT06369064

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of continuous dialysis used in the ICU for patients with sudden kidney failure. One method uses a citrate-based blood thinner, the other uses heparin. The goal is to see if the citrate method is just as effective at removing waste from the blood. 80 adult ICU patients will be randomly assigned to one of the two methods, and their blood will be tested after 24 hours.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Dialysis procedure (CVVHD with citrate anticoagulation vs. CVVHDF with heparin anticoagulation)

What this could lead to

If successful, this could show that a simpler, citrate-based dialysis method works just as well as the standard heparin-based method, potentially simplifying care for ICU patients with kidney failure.

What could go wrong

This is a small, early-stage study (80 patients) at a single hospital, so results may not apply to all patients. The study compares two established techniques, so no breakthrough is expected.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Nimes

    RECRUITING

    Nîmes, 30029, France

    Contact

    Contact Email: •••••@•••••

    Contact

    Contact