Dialysis showdown: which method cleans blood better in the ICU?
NCT ID NCT06369064
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of continuous dialysis used in the ICU for patients with sudden kidney failure. One method uses a citrate-based blood thinner, the other uses heparin. The goal is to see if the citrate method is just as effective at removing waste from the blood. 80 adult ICU patients will be randomly assigned to one of the two methods, and their blood will be tested after 24 hours.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Dialysis procedure (CVVHD with citrate anticoagulation vs. CVVHDF with heparin anticoagulation)
- What this could lead to
- If successful, this could show that a simpler, citrate-based dialysis method works just as well as the standard heparin-based method, potentially simplifying care for ICU patients with kidney failure.
- What could go wrong
- This is a small, early-stage study (80 patients) at a single hospital, so results may not apply to all patients. The study compares two established techniques, so no breakthrough is expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ACUTE KIDNEY INJURY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU de Nimes
RECRUITINGNîmes, 30029, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Which emergency dialysis saves more lives? a new study investigates
- A simple sensor on the back could warn of kidney danger during heart surgery
- Can a common blood thinner be safe for ICU patients with liver issues?
- A urine test that could foresee kidney danger in the ICU
- Which citrate solution minimizes metabolic chaos in kidney therapy?
- A wearable sensor might spot kidney danger before it strikes