Gut bacteria linked to narcolepsy? new study investigates

NCT ID NCT06292598

Recruiting now Knowledge-focused Sponsor: Centre Hospitalier Universitaire de Nīmes Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether changes in gut bacteria and increased intestinal permeability can trigger inflammation that damages brain cells in people with type 1 narcolepsy. Researchers will collect blood, stool, and spinal fluid samples from 120 participants to measure bacterial DNA and immune markers. The goal is to understand the role of gut health in this rare sleep disorder.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could reveal how gut bacteria contribute to narcolepsy, pointing toward new ways to diagnose or treat the condition.
What could go wrong: This is an observational study, not a treatment trial. It may not find a clear link, and results may not lead to immediate therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

narcolepsy-cataplexy syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BACTERIAL TRANSLOCATION NARCOLEPSY TYPE 1

Contacts and locations

Locations

Centre Hospitalier Universitaire de Montpellier
RECRUITING

Montpellier, France
Nîmes University Hospital
NOT_YET_RECRUITING

Nîmes, Gard, 30029, France

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