New diuretic strategy aims to improve heart failure care in the ER

NCT ID NCT04481919

First seen Jan 05, 2026 · Last updated Jun 14, 2026 · Updated 23 times

Summary

This study compares a structured diuretic treatment plan guided by urine sodium levels to standard care for adults with acute heart failure in the emergency department. About 474 participants will be randomly assigned to one of two groups. The goal is to see if the urine-sodium-guided approach leads to better clinical outcomes and less congestion.

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Contacts and locations

Locations

  • VA Tennessee Valley Health Service

    Nashville, Tennessee, 37232, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.