New Valve-in-Valve procedure offers hope for failing heart valves

NCT ID NCT03193801

Ongoing Disease control Sponsor: Edwards Lifesciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a less invasive way to replace a failing mitral valve in the heart. About 53 people who already have a surgical valve that is not working well will receive a new valve placed inside the old one using a thin tube. The goal is to see if this procedure is safe and helps people live longer and feel better.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder heart failure mitral valve disorder mitral valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE MITRAL VALVE DISEASE MITRAL VALVE INSUFFICIENCY MITRAL VALVE REGURGITATION

Contacts and locations

Locations

Barnes-Jewish Hospital/ Washington University

St Louis, Missouri, 63110, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
Emory University

Atlanta, Georgia, 30322, United States
Instituto Dante Pazzanese de Cardiologia

Vila Mariana, São Paulo, 04012-909, Brazil
Instituto do Coração da Universidade de São Paulo

Cerqueira César, São Paulo, 05403-900, Brazil
Mayo Clinic

Rochester, Minnesota, 55905, United States
NYU Lagone Medical Center

New York, New York, 10016, United States
Northshore University Health System Research Institution

Evanston, Illinois, 60201, United States
Northwestern University

Chicago, Illinois, 60611, United States
Providence Heart & Vascular Institution

Portland, Oregon, 97225, United States
The Heart Hospital of Baylor Plano

Plano, Texas, 75093, United States
The Prince Charles Hospital

Chermside, Queensland, 4032, Australia

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