New Valve-in-Valve procedure offers hope for failing heart valves

NCT ID NCT03193801

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a less invasive way to replace a failing mitral valve in the heart. About 53 people who already have a surgical valve that is not working well will receive a new valve placed inside the old one using a thin tube. The goal is to see if this procedure is safe and helps people live longer and feel better.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder heart failure mitral valve disorder mitral valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Barnes-Jewish Hospital/ Washington University

    St Louis, Missouri, 63110, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Instituto Dante Pazzanese de Cardiologia

    Vila Mariana, São Paulo, 04012-909, Brazil

  • Instituto do Coração da Universidade de São Paulo

    Cerqueira César, São Paulo, 05403-900, Brazil

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • NYU Lagone Medical Center

    New York, New York, 10016, United States

  • Northshore University Health System Research Institution

    Evanston, Illinois, 60201, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Providence Heart & Vascular Institution

    Portland, Oregon, 97225, United States

  • The Heart Hospital of Baylor Plano

    Plano, Texas, 75093, United States

  • The Prince Charles Hospital

    Chermside, Queensland, 4032, Australia