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Could a sleep apnea machine boost heart efficiency? new study investigates

NCT ID NCT02116140

Ongoing Knowledge-focused Sponsor: Ottawa Heart Institute Research Corporation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether long-term use of a breathing device called adaptive servo-ventilation (ASV) can improve how the heart uses energy and how nerves work in people with heart failure and sleep apnea. Researchers will use PET scans to measure heart metabolism and nerve function in 60 participants over six months. The goal is to understand if ASV therapy helps the heart work more efficiently, which could inform better treatments for these conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
adaptive servo-ventilation (ASV) therapy
What this could lead to
If successful, this could clarify whether ASV therapy improves heart energy efficiency and nerve function in heart failure patients with sleep apnea, potentially guiding future treatments.
What could go wrong
This is a small, early-stage substudy (60 participants) focused on measuring biological markers, not clinical outcomes. Results may not translate to broader patient benefits or confirm effectiveness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

central sleep apnea syndrome heart failure obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CENTRAL SLEEP APNEA HEART FAILURE OBSTRUCTIVE SLEEP APNEA

Contacts and locations

Locations

  • University of Ottawa Heart Institute

    Ottawa, Ontario, K1Y 4W7, Canada

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