Heart repair with stem cells: a new hope for chronic heart failure?
NCT ID NCT06340048
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether injecting lab-grown heart muscle cells (HiCM-188) into the heart during bypass surgery can safely help people with severe chronic heart failure. About 36 adults with damaged heart tissue and reduced pumping function will receive the cell injection. The main goal is to check for serious side effects within the first month, while also looking at heart function and tumor risk over a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Allogeneic human pluripotent stem cell-derived cardiomyocytes (HiCM-188)
- What this could lead to
- If successful, this could lead to a new way to repair damaged heart muscle in people with severe heart failure, potentially improving heart function and quality of life.
- What could go wrong
- This is an early-phase trial with only 36 participants, so results may not apply to everyone. Risks include serious side effects like arrhythmias, heart attack, or stroke, and it is unknown if the cells will work long-term.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEART FAILURE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
TEDA International Cardiovascular Hospital
Tianjin, Tianjin Municipality, 300457, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could delaying kidney implant during heart transplant reduce complications?
- A simple conversation could change how heart failure patients care for themselves
- A picture-based lesson may help heart failure patients spot trouble early
- Can a Two-Drug punch early in hospitalization tame heart failure?
- Bedside flu shot for heart patients: a simple strategy to save lives?
- AI takes on sonographers: a 4,000-Patient trial to sharpen heart imaging