Can a 'N-of-1' trial help heart failure patients find their perfect dose?
NCT ID NCT07489352
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a personalized approach to find the best beta-blocker dose for older adults with heart failure. Fifty participants will either receive the N-of-1 intervention (testing different doses in 2-week cycles) or enhanced usual care. The goal is to see if this patient-driven method helps achieve higher, better-tolerated doses.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
beta-blocker (metoprolol, carvedilol, or bisoprolol)
What this could lead to
If successful, this approach could help doctors and patients personalize beta-blocker dosing, improving heart failure management without side effects.
What could go wrong
This is a small, early-stage behavioral study (not testing a new drug). It may not show clear benefits, and results might not apply to all patients.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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