New heart preservation method could expand donor pool for transplants

NCT ID NCT05881278

Ongoing Disease control Sponsor: XVIVO Perfusion Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at a new way to keep donor hearts healthy during transport for transplantation. It involves 141 adults with heart failure who are on the transplant list. The goal is to see if this method is safe and effective for using hearts from extended criteria donors.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE TRANSPLANT; FAILURE, HEART

Contacts and locations

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Locations

Cedars-Sinai

Los Angeles, California, 90048, United States
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Columbia University Irving Medical Center/New York Presbyterian Hospital

New York, New York, 10032, United States
David Geffen School of Medicine at UCLA

Los Angeles, California, 90095, United States
Duke University

Durham, North Carolina, 27710, United States
Emory University

Atlanta, Georgia, 30322, United States
Johns Hopkins Medicine

Baltimore, Maryland, 21287, United States
Montefiore Medical Center

The Bronx, New York, 10467, United States
NYU Langone Health

New York, New York, 10016, United States
Northwestern Memorial Hospital

Chicago, Illinois, 60611, United States
Ohio State University

Columbus, Ohio, 43210, United States
Stanford Medicine

Palo Alto, California, 94304, United States
UT Southwestern Medical Center

Dallas, Texas, 75390, United States
University of California San Diego

La Jolla, California, 92037, United States
University of Maryland Medical Center/University of Maryland, Baltimore

Baltimore, Maryland, 21201, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15213, United States
University of Washington Medical Center

Seattle, Washington, 98195, United States
Vanderbilt University

Nashville, Tennessee, 37232, United States
Washington University - Barnes Jewish Hospital

St Louis, Missouri, 63110, United States

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