Scientists collect heart tissue to unlock heart failure secrets
NCT ID NCT02683681
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study collects tissue and blood samples from 200 people with advanced heart failure who are getting a heart pump or transplant. Researchers will use these samples to learn more about the disease. No new treatments are being tested, and the study does not change how patients are treated.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this registry could help researchers better understand heart failure and potentially guide future treatments.
- What could go wrong
- This is an observational study, not a treatment trial. It collects samples but does not test any therapy, so it won't directly help participants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
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Jun 2008
- Expected to finish
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Dec 2036
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who are seen at participating facilities for left ventricular assist device (LVAD) implantation and/or heart transplantation will be screened for this registry study.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients must be in one of the following groups: 1.1. Patients must be eligible for a - * LVAD implantation or * Heart transplantation 1.2. Patients must be scheduled for another type of cardiac surgery during which tissue is excised that would normally be discarded after surgery. 1.3. Patients must have a VAD already implanted as destination therapy with no cardiac surgery scheduled at the time of consent. 2. Patients must agree to one or more blood and/or cardiac tissue sample donation(s), and longterm storage of these biological samples. 3. Patients must be \> 18 years of age. Exclusion Criteria: Patients will be excluded from the study if any of the following conditions are present: 1. The patient or the patient's personal representative is unable or unwilling to give written informed consent for participation. 2. Patients who are less than 18 years of age.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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