Heart failure drug samtasu put to the test in 1,600-Patient safety survey
NCT ID NCT05712746
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study monitors the safety of the intravenous drug Samtasu (tolvaptan sodium phosphate) in people with heart failure who have fluid overload. Researchers will track side effects, including serious events and off-label use, in about 1,600 patients. The goal is to confirm the drug's safety in real-world use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Samtasu (tolvaptan sodium phosphate)
- What this could lead to
- If this study shows Samtasu is safe in a broad group of heart failure patients, it could support its continued use to help remove excess fluid and ease symptoms.
- What could go wrong
- This is an observational safety study, not a test of effectiveness. It may reveal unexpected side effects or find that the drug does not work well in certain patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Pharmacovigilance Department
Osaka, 540-0021, Japan
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