Could ditching Beta-Blockers boost quality of life for seniors with heart failure?
NCT ID NCT07298993
First seen Jun 24, 2026 · Last updated Jul 16, 2026 · Updated 3 times
Summary
This study looks at whether gradually stopping beta-blockers (medicines often used for heart failure) can improve symptoms and daily function in adults aged 60 and older with a specific type of heart failure called HFpEF. About 240 participants will either taper off their beta-blocker or continue it, and researchers will track hospitalizations, quality of life, and mood over 4 months. The goal is to see if removing these medications, when they may no longer be needed, leads to better outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- beta-blockers (atenolol, bisoprolol, carvedilol, metoprolol succinate, metoprolol tartrate)
- What this could lead to
- If successful, this could show that stopping unnecessary beta-blockers helps older adults with HFpEF feel better and have fewer hospitalizations.
- What could go wrong
- This is a small, early-phase study (240 participants) focused on symptom improvement, not a cure. Results may not apply to all patients, and stopping beta-blockers could carry risks like increased heart rate or blood pressure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Kaiser Permanente Northern California (KPNC)
Pleasanton, California, 94588, United States
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