New heart device aims to ease pressure in failing hearts

NCT ID NCT03523416

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early study tests a device that creates a small opening between the upper chambers of the heart to relieve pressure in people with symptomatic heart failure. The study includes 71 participants and focuses on safety and whether the device works as intended. It is not a cure but aims to control the disease and improve symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Transcatheter Atrial Shunt System (a device that creates a small passage between the upper chambers of the heart)

What this could lead to

If it works, this device could offer a new way to manage heart failure symptoms and reduce hospital stays.

What could go wrong

This is an early feasibility study with only 71 people, so it's too soon to know if it's safe or effective. There are risks of heart, brain, or kidney complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart failure systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Abbott Northwestern

    Minneapolis, Minnesota, 55407, United States

  • Atrium Health

    Charlotte, North Carolina, 28203, United States

  • Kansas University Medical Center

    Kansas City, Kansas, 66160, United States

  • Lankenau Institute for Medical Research

    Wynnewood, Pennsylvania, 19096, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • St. Vincent Medical Group

    Indianapolis, Indiana, 46260, United States

  • Swedish Medical Center

    Seattle, Washington, 98122, United States

  • The Christ Hospital

    Cincinnati, Ohio, 45219, United States

  • The Ohio State University Medical Center

    Columbus, Ohio, 43210, United States

  • UC San Diego Health

    La Jolla, California, 92037, United States

  • University California San Francisco

    San Francisco, California, 94143, United States

  • University of Florida Health - Jacksonville

    Jacksonville, Florida, 32209, United States