Can we predict who benefits from a heart device? new study aims to find out
NCT ID NCT06977217
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is for heart failure patients who do not have a specific heart rhythm pattern called left bundle branch block (non-LBBB). These patients often get a device called CRT-D, which combines a pacemaker and a defibrillator, but not everyone responds well. Researchers will follow 270 patients for 12 months to see if certain tests before implantation can predict who will improve. The goal is to develop a scoring system to help doctors choose the right patients for this therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cardiac resynchronization therapy with a defibrillator (CRT-D)
What this could lead to
If successful, this could help doctors identify which heart failure patients without a specific ECG pattern will benefit most from CRT-D, improving outcomes and avoiding unnecessary procedures.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test a new therapy. The findings may not apply to all patients, and the predictive score needs further validation before clinical use.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Rochester Medical Center
Rochester, New York, 14642, United States