Ketone drink shows promise for heart failure in small study

NCT ID NCT05651529

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a single dose of a ketone salt supplement could improve heart function in 20 people with stable heart failure. Participants took either the ketone supplement or a carbohydrate placebo before a heart MRI. The goal was to see if the supplement could help the heart pump more effectively.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

exogenous ketone salt supplement

What this could lead to

If it works, this could point toward a simple dietary supplement to help improve heart function in people with heart failure.

What could go wrong

This is a very small, early-stage study with only 20 participants. The supplement was taken just once, so any effects may be temporary or not meaningful in the long run.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEART FAILURE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

heart failure Ketosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Hospitalier Universitaire de Sherbrooke, departement de cardiologie

    Sherbrooke, Quebec, J1H 5N4, Canada

  • Centre Hospitalier Universitaire de Sherbrooke, departement de médecine

    Sherbrooke, Quebec, J1H 5N4, Canada