Ketone drink shows promise for heart failure in small study

NCT ID NCT05651529

Completed Symptom relief Sponsor: Université de Sherbrooke Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a single dose of a ketone salt supplement could improve heart function in 20 people with stable heart failure. Participants took either the ketone supplement or a carbohydrate placebo before a heart MRI. The goal was to see if the supplement could help the heart pump more effectively.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: exogenous ketone salt supplement
What this could lead to: If it works, this could point toward a simple dietary supplement to help improve heart function in people with heart failure.
What could go wrong: This is a very small, early-stage study with only 20 participants. The supplement was taken just once, so any effects may be temporary or not meaningful in the long run.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure Ketosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

Locations

Centre Hospitalier Universitaire de Sherbrooke, departement de cardiologie

Sherbrooke, Quebec, J1H 5N4, Canada
Centre Hospitalier Universitaire de Sherbrooke, departement de médecine

Sherbrooke, Quebec, J1H 5N4, Canada

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