New heart pacing technique could offer alternative for heart failure patients
NCT ID NCT04409119
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compared a newer pacing method, called HIS or left bundle branch (LBB) pacing, to the standard biventricular pacing in 150 heart failure patients with a specific heart electrical problem (left bundle branch block). The goal was to see if the new method could improve heart function and symptoms as well as or better than the standard approach. Researchers measured changes in heart size and pumping ability after 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HIS/LBB pacing (a device-based pacing procedure)
What this could lead to
If successful, this could offer a more natural pacing method for heart failure patients, potentially improving heart function and symptoms.
What could go wrong
This is a completed study with 150 participants, but it is not a large-scale trial. The new pacing method may not work for everyone and could have implantation challenges or risks like lead dislodgement.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Rigshospitalet
Copenhagen, Capital Region, 2100, Denmark