Heart failure drug shot could replace IV needles

NCT ID NCT04384653

Completed Disease control Sponsor: SQ Innovation, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new way to give the heart failure drug furosemide: as a shot under the skin instead of through an IV. Twenty adults with chronic heart failure received both versions to compare how much drug gets into the body. The goal is to see if the shot works well enough to offer a simpler, more convenient option for patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: furosemide
What this could lead to: If successful, this could offer a more convenient way to give furosemide to heart failure patients, potentially allowing treatment at home instead of in a hospital.
What could go wrong: This is an early-stage study with only 20 people, so results may not apply to everyone. The new shot is not expected to work exactly like the IV version, and it may not be as effective or could cause skin reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

Locations

Accel Research Sites - DeLand Clinical Research Unit

DeLand, Florida, 32720, United States

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Other studies related to the condition(s) this trial covers.