New wearable pump could send heart failure patients home early

NCT ID NCT05419115

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This phase 2 trial tested whether a new wearable pump that delivers a water pill (furosemide) under the skin could help heart failure patients leave the hospital earlier. 172 adults admitted for heart failure were randomly assigned to either go home with the pump or stay in the hospital for standard IV treatment. The main goal was to see if the home group spent more days alive and out of the hospital within 30 days.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
furosemide (a water pill) given under the skin via a wearable pump
What this could lead to
If it works, this could allow heart failure patients to finish their treatment at home instead of in the hospital, improving comfort and freeing up hospital beds.
What could go wrong
This is a small, early-phase trial (172 people) testing a new device and drug formulation. The device is not yet approved, and the approach may not prove safe or effective enough for routine use.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Basildon University Hospital

    Basildon, England, SS16 5NL, United Kingdom

  • Blackpool Victoria Hospital

    Blackpool, England, FY3 8NR, United Kingdom

  • Forth Valley Hospital

    Larbert, Scotland, FK5 4WR, United Kingdom

  • Glasgow Royal Infirmary

    Glasgow, Scotland, G12 8TA, United Kingdom

  • Glenfield Hospital

    Leicester, England, LE3 9QP, United Kingdom

  • Leeds General Infirmary

    Leeds, England, LS1 3EX, United Kingdom

  • Manchester Heart Centre

    Manchester, England, M13 9WL, United Kingdom

  • Ninewells Hospital

    Dundee, Scotland, DD1 9SY, United Kingdom

  • Queen Alexandra Hospital

    Portsmouth, England, PO6 3LY, United Kingdom

  • Queen Elizabeth University Hospital

    Glasgow, Strathclyde, G51 4TF, United Kingdom

  • Southmead Hospital

    Bristol, England, BS10 5NB, United Kingdom

  • St Thomas' Hospital

    London, England, SE1 7EH, United Kingdom

  • St. George's University of London

    London, England, SW17 0RE, United Kingdom

  • Stoke Mandeville Hospital

    Aylesbury, England, HP21 8AL, United Kingdom

  • Sunderland Royal Hospital

    Sunderland, England, SR4 7TP, United Kingdom

  • The Great Western Hospital

    Swindon, United Kingdom, SN3 6BB, United Kingdom

  • University Hospital Ayr

    Ayr, Scotland, KA6 6DX, United Kingdom

  • University Hospital Monklands

    Airdrie, ML6 0JS, United Kingdom

  • University Hospital Southampton

    Southampton, United Kingdom

  • University Hospital of North Tees

    Hardwick, England, TS19 8PE, United Kingdom

  • University Hospitals Dorset

    Bournemouth, England, BH7 7DW, United Kingdom

  • Wycombe General Hospital

    High Wycombe, England, HP11 2TT, United Kingdom

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