Old heart drug digoxin gets a second look: can low doses save lives?

NCT ID NCT03783429

First seen May 01, 2026 · Last updated May 15, 2026 · Updated 2 times

Summary

This study tested whether a low dose of digoxin, a very old and cheap heart drug, can help people with chronic heart failure. About 982 adults with heart failure and reduced pumping function took either digoxin or a placebo. The goal was to see if digoxin could reduce hospital stays and deaths from heart problems.

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Contacts and locations

Locations

  • Admiraal de Ruyter Ziekenhuis

    Goes, Netherlands

  • Alrijne Ziekenhuis

    Leiden, Netherlands

  • Amphia Ziekenhuis

    Breda, Netherlands

  • Antonius Ziekenhuis Sneek

    Sneek, Netherlands

  • Beatrix Ziekenhuis

    Gorinchem, Netherlands

  • Bethesda

    Hoogeveen, Netherlands

  • BovenIJ Ziekenhuis

    Amsterdam, Netherlands

  • Bravis ziekenhuis

    Roosendaal, Netherlands

  • Deventer Ziekenhuis

    Deventer, Netherlands

  • Diak. Utrecht

    Utrecht, Netherlands

  • Elisabeth-Tweesteden Ziekenhuis

    Tilburg, Netherlands

  • Elkerliek Ziekenhuis

    Helmond, Netherlands

  • Erasmus Medisch Centrum

    Rotterdam, Netherlands

  • Franciscus Gasthuis

    Rotterdam, Netherlands

  • Franciscus Vlietland

    Schiedam, Netherlands

  • Gelre Ziekenhuizen

    Apeldoorn, Netherlands

  • Groene Hart Ziekenhuis

    Gouda, Netherlands

  • Haaglanden Medisch Centrum

    The Hague, Netherlands

  • Ijsselland Ziekenhuis

    Capelle aan den IJssel, Netherlands

  • Ikazia Ziekenhuis

    Rotterdam, Netherlands

  • Isala Diaconessenhuis

    Meppel, Netherlands

  • Maastricht UMC+

    Maastricht, Netherlands

  • Martini Ziekenhuis

    Groningen, Netherlands

  • Meander Medisch Centrum

    Amersfoort, Netherlands

  • Medisch Centrum Leeuwarden

    Leeuwarden, Netherlands

  • Máxima Medisch Centrum

    Veldhoven, Netherlands

  • Noordwest Ziekenhuisgroep

    Alkmaar, Netherlands

  • Radboud University Medical Center

    Nijmegen, Netherlands

  • Refaja

    Stadskanaal, Netherlands

  • Reinier de Graaf Gasthuis

    Delft, Netherlands

  • Rijnstate Ziekenhuis

    Arnhem, Netherlands

  • Rode Kruis Ziekenhuis

    Beverwijk, Netherlands

  • Saxenburgh MC

    Hardenberg, Netherlands

  • Scheper Ziekenhuis

    Emmen, Netherlands

  • Slingeland Ziekenhuis

    Doetinchem, Netherlands

  • Spaarne Gasthuis

    Haarlem, Netherlands

  • Tergooi

    Blaricum, Netherlands

  • University Medical Center Groningen

    Groningen, Netherlands

  • Van Weel Bethesda

    Dirksland, Netherlands

  • Zaans Medisch Centrum

    Zaandam, Netherlands

  • Ziekenhuis Gelderse Vallei

    Ede, Netherlands

  • Ziekenhuis St Jansdal

    Harderwijk, Netherlands

  • Zorggroep Twente

    Almelo, Netherlands

  • Zuyderland Medisch Centrum

    Heerlen, Netherlands

Conditions

Explore the condition pages connected to this study.