Insomnia

This phase 3 study evaluates the safety of HS-10506, an experimental insomnia medication, in 600 Chinese adults aged 18 to 64 with insomnia disorder. Researchers track side effects, serious adverse events, and specific safety concerns over both short and long-term use. The goal i…

This study tests if special reflective roof coatings can lower indoor temperatures and improve health in Fiji. About 800 households will receive either a cool roof or usual care. Researchers will measure heart rate, blood sugar, depression, and other heat-related symptoms to see …

This study tests whether a traditional Chinese herbal formula (Tiaoshen Anti-cancer granules) combined with cognitive behavioral therapy for insomnia (CBT-I) can improve sleep and possibly extend survival in 360 women with advanced ovarian cancer. Participants will receive either…

This study will test whether applying a special heat-reflecting coating to roofs can improve the health and well-being of 800 households in Colima, Mexico. The coating is designed to keep homes cooler indoors, which may help lower heart rate, improve blood sugar control, reduce d…

This study tests whether a drug called dexmedetomidine, given through an IV to induce sleep, can help people with severe insomnia that hasn't improved with other treatments. 180 adults aged 18-65 will receive either the drug plus standard oral medication or standard medication al…

This study will develop and test artificial intelligence (AI) to automatically classify sleep stages from overnight sleep recordings (polysomnography). The goal is to see if the AI can match or beat expert manual scoring, with the aim of supporting diagnosis of chronic insomnia a…

This study tests whether a digital program that combines cognitive behavioral therapy for insomnia with circadian rhythm coaching can prevent depressive symptoms from worsening in college students aged 18-24 who have trouble falling asleep and tend to be night owls. Participants …

This study tests a new approach to prevent delirium (sudden confusion) in intensive care patients. It uses an artificial intelligence system to help nurses make better care decisions and virtual reality to keep patients mentally active. The goal is to reduce the risk of long-term…

This study tests whether a digital insomnia treatment (dCBT-I) can prevent depression in perimenopausal women with sleep problems. 230 women will receive either dCBT-I or sleep hygiene education and be followed for 2 years. The goal is to see if improving sleep reduces depressive…

This study tests whether a daily capsule containing lotus seed and rice germ extract, called ZenRest™, can improve sleep quality in menopausal women aged 40 to 65 who have mild-to-moderate sleep problems. Participants take either the supplement or a placebo for six weeks, and sle…

This study tests a program to help adult patients sleep better in the intensive care unit (ICU) after surgery. The program includes sleep education, earplugs and eye masks, reducing noise and light at night, and grouping nursing tasks to avoid waking patients. Researchers will co…

This pilot study tests whether a headband that delivers timed sound pulses (pink noise) can improve sleep in 25 people with both depression and insomnia. Participants wear the device nightly for four weeks, alternating between active stimulation and sham (placebo) sound. The goal…

This study tests a headset called HALO Clarity™ that sends mild electrical currents to the brain to help people with moderate-to-severe insomnia sleep better. 160 adults will use either the active device or a sham (fake) device at home for 4 weeks, then be followed for another 4 …

This study tests a two-session Zoom-based therapy designed to change beliefs about mental health treatment in Deaf adults who are not currently in care. Researchers will compare those who receive the therapy to a waitlist group to see if it increases treatment-seeking and reduces…

This study tests whether neurofeedback—a type of brainwave training—can help adults with episodic migraine have fewer and less severe headaches. Participants will undergo 60 sessions over 12 weeks, learning to regulate their brain activity through real-time feedback. The goal is …

This study tests whether listening to ASMR or white noise before bed can improve sleep quality for adults recovering from elective lower leg surgery. Participants are randomly assigned to listen to a 30-minute ASMR recording, white noise, or receive routine care. Sleep quality is…

This study tests whether an online sleep improvement program can help people with ongoing concussion symptoms. 70 adults with insomnia after a concussion will use a digital platform for 8 weeks. The goal is to see if better sleep reduces symptoms and improves brain and heart func…

This study tests whether the sleep medication lemborexant can improve both sleep and motor symptoms in people with Parkinson's disease. Forty-four participants will take either lemborexant or a placebo nightly for 28 days. Researchers will measure changes in sleep quality and mov…

This study tests whether a simple, low-cost sleep hygiene education program can improve insomnia as effectively as a standard cognitive behavioral therapy app. About 264 adults with insomnia will be randomly assigned to the education program, the app, or a control group. The goal…

This study tests whether a non-electric, hand-held temple massager—used daily for 4 weeks with a special lotion and optional lavender aromatherapy—can lower stress, improve emotional wellbeing, sleep quality, and overall quality of life in women aged 35 to 65. Participants use th…

This study tests whether learning progressive muscle relaxation and deep breathing exercises can improve sleep for cancer patients receiving chemotherapy. About 40 adults aged 40-60 with poor sleep will be split into two groups: one gets relaxation training plus usual care, the o…

This pilot study tests whether simple bedroom changes and sleep tips can improve sleep for older adults (65+) who live alone, have memory concerns, and struggle with insomnia. Over 8 weeks, researchers will visit participants' homes to adjust the bedroom environment and provide s…

This study tests a new smart home system that uses artificial intelligence to deliver cognitive behavioral therapy for insomnia to young adult cancer survivors. The system includes a smart speaker, smart lighting, and a special Wi-Fi router. Researchers will compare it to standar…

This study tests a sleep treatment called TranS-C, adapted for veterans with PTSD and sleep problems. The goal is to improve sleep, reduce nightmares, and help veterans function better in daily life. 182 veterans will receive either the sleep treatment or usual care to see if it …

This study tests whether suvorexant, a medication already approved for insomnia, can help Veterans with PTSD and sleep problems better unlearn fear responses. About 40 Veterans will take either suvorexant or a placebo for 7 nights while researchers measure their skin responses to…

This study tests whether a daily supplement made from salmon protein (ProGo®) can help menopausal women manage their weight and improve quality of life. About 100 healthy, overweight women aged 40-65 will take either a low or high dose of ProGo® or a placebo for 18 weeks. Researc…

This study tests whether cognitive behavioral therapy for insomnia (CBT-I) can reduce insomnia severity in physically active adults aged 30-59. Fifty participants will either receive 6 weeks of CBT-I or no treatment. The main goal is to see if CBT-I improves sleep quality and red…

This study tests whether smelling lavender essential oil can improve sleep in women aged 60 and older who are in the hospital and have trouble sleeping. Sixty-four participants will either receive lavender aromatherapy or a placebo, and their sleep quality will be measured using …

This study tests a nurse-led program for insomnia that also uses a health education chatbot. 80 adults with sleep problems will either get the program plus chatbot or just track their sleep. The goal is to see if the chatbot-assisted approach improves sleep, anxiety, depression, …

This study tests whether walking with a robot dog can improve sleep, reduce fatigue, and enhance quality of life in children aged 2-7 who are undergoing cancer treatment. Forty children will be randomly assigned to either robot-dog-assisted walks or usual care. The goal is to see…

This study tests whether a drug called gamma-hydroxybutyrate (GHB) can help intensive care patients get better deep sleep. Sleep problems are very common in the ICU and can lead to serious issues like confusion and longer recovery. The trial will give GHB or a placebo to 24 adult…

This pilot study tests whether cold-water immersion, sauna use, or a combination of both can improve sleep quality in 45 military cadets. Participants will do 14 daily sessions of one of the therapies while wearing an Oura Ring to track sleep. The goal is to see if these temperat…

This study tests whether low-intensity focused ultrasound (LIFU) applied to a nerve cluster in the neck can improve sleep quality and heart rate control in people recovering from heart surgery. 200 participants will receive either real or sham ultrasound daily for 3-7 days after …

This study tests whether a non-invasive magnetic brain stimulation treatment (rTMS) can improve sleep in people with chronic insomnia. About 70 adults aged 18 to 85 will receive six 25-minute sessions over two weeks. The goal is to see if insomnia severity and sleep patterns impr…

This study tests whether taking inulin (a prebiotic fiber) and spirulina (a nutrient-rich algae), alone or together, can improve sleep in adults aged 18 to 60 with chronic insomnia. Over 12 weeks, 180 participants will take one of four options: inulin, spirulina, both, or a place…

This study tests whether an artificial intelligence (AI)-guided sleep program is practical and well-liked by adults aged 60 and older who have both insomnia and mild memory concerns. Researchers will enroll 60 participants to check how many people join, stick with the program, an…

This phase 3 study tests whether the drug HS-10506 helps Chinese adults with insomnia fall asleep faster and wake up less during the night. About 732 participants will receive either the drug or a placebo for up to 84 days. The study measures sleep using both overnight lab tests …

This study tests a smartphone app called BELL-001 that plays sounds in sync with your breathing to help you relax and fall asleep. Forty adults with insomnia will use the app every night for 12 weeks. Researchers will track sleep quality, mood, and safety to see if this drug-free…

This study tests whether reflexology (foot massage) or progressive muscle relaxation can reduce fatigue in people on hemodialysis. Sixty patients aged 50-70 will be split into three groups: reflexology, relaxation, or standard care. Fatigue and sleep quality will be measured afte…

This study tests whether electroacupuncture can improve sleep in people with long-term sciatica caused by a slipped disc. About 114 adults with chronic insomnia and leg pain will receive either real electroacupuncture or a sham version three times a week for four weeks. Researche…

This study tests whether combining thread embedding acupuncture with ear acupressure can improve sleep in people with non-organic insomnia. Seventy adults aged 40 to 75 will receive either personalized or standard treatment over 8 weeks. Researchers will also check if changes in …

This study tests a sleep program for people hospitalized after a leg injury that needed surgery. The program includes sleep medicine, melatonin, and sleep tips. Researchers want to see if it helps patients sleep longer and better, and if it reduces the need for strong painkillers…

This study tests whether a short, telephone-delivered insomnia treatment (BBTI) can improve sleep and cognitive function in 214 older adults with HIV, compared to a mindfulness approach (BMT). Participants will complete four weekly phone sessions and attend in-person visits for s…

This study tests a slow-release melatonin (PedPRM) in 120 children aged 6 to 18 who have anorexia nervosa and trouble sleeping. Participants take either melatonin or a placebo for 13 weeks. The goal is to see if it safely improves total sleep time and related symptoms like anxiet…

This study tests a structured sleep hygiene education program for adults with insomnia. Ten Hong Kong Chinese participants will learn behavior-change techniques to improve their sleep. The goal is to see if this low-cost, non-drug approach is feasible and effective for reducing i…

This study tests whether THC (with or without CBD) can improve sleep in people with solid organ cancer who have insomnia. About 69 participants will receive either THC, a THC/CBD mix, or a placebo as a liquid under the tongue. The goal is to see if these cannabis-based compounds …

This study will test a 4-step training program designed to help teenagers aged 13-18 reduce their social media addiction and improve their mental health. The program uses education, cognitive-behavioral techniques, and relapse prevention. Researchers will compare a group that rec…

This study tests whether a special smartwatch can improve sleep in warfighters who have trouble sleeping due to PTSD, traumatic brain injury, or stress. The watch detects signs of stress during sleep, like a fast heart rate, and gives gentle vibrations to calm the body without wa…

This study tests whether daridorexant, a sleep medication, can help people who have both major depression and insomnia. Researchers want to see if it improves sleep quality and also eases depressive symptoms. About 134 adults will take either daridorexant or a placebo for three m…

This study looks at people who have both sleep apnea and chronic insomnia. All 120 participants will receive standard CPAP therapy for sleep apnea. Half will also get a digital program to treat their insomnia starting at the same time as CPAP. The other half will follow usual car…

This study looks at whether a type of talk therapy for insomnia (CBT-I) can also improve markers of metabolic syndrome, like blood sugar and insulin resistance. Twenty adults with insomnia and higher body weight will be randomly assigned to CBT-I or basic sleep tips for 5 weeks. …

This study tests if a gentle brain stimulation technique called tDCS can improve movement, balance, fatigue, sleep, and thinking in people with multiple sclerosis. Forty adults with MS will receive either real or sham stimulation over two weeks. Researchers will check if the trea…

This study tests whether a low-level laser applied to specific points on the ear can improve sleep in women with breast cancer who have insomnia. Seventy participants will receive either real or sham laser acupuncture twice a week for five weeks. Sleep quality, fatigue, and mood …

This pilot study will test whether a 6-week program of cognitive behavioral therapy for insomnia (CBT-I) can improve sleep and blood sugar control in 30 adults aged 40+ with type 2 diabetes and chronic insomnia. Participants are randomly assigned to CBT-I or usual care, and outco…

This study tests a psychological program designed to improve sleep quality in female university students aged 18-25 who have insomnia. The goal is to see if better sleep helps their thinking skills and academic performance. About 35 participants will take part in the program and …

This study looks at whether adding sleep-focused treatments to standard psychiatric care can reduce suicide risk in young adults. About 90 college students with suicidal thoughts and sleep problems will be randomly assigned to one of three sleep interventions. Researchers will tr…

This study tests whether two relaxation techniques—Benson relaxation and progressive muscle relaxation—can help reduce pain and improve sleep quality in 160 patients who have had a lung lobectomy. Participants will practice these techniques after surgery, and their pain levels an…

This study looks at whether doing physical therapy in the daytime or evening helps people with a herniated disc in their lower back sleep better and feel less sleepy during the day. It includes 60 adults who also have a high risk for obstructive sleep apnea. Participants will be …

This study tests a wearable smart eye-mask that combines gentle heat and massage with voice-guided sleep therapy to help people who have both insomnia and sleep apnea. The 4-year project will first explore how the condition works, then develop the device, and finally test it in 1…

This study tests whether a mobile app or virtual reality program that teaches mindfulness and breathing exercises can lower stress, burnout, and improve sleep and thinking in nurses who work rotating shifts. 300 nurses will be split into four groups: one gets health education onl…

This study tests whether doing progressive relaxation exercises at times matched to each patient's natural circadian rhythm can help manage symptoms, improve sleep quality, increase comfort, and boost mental well-being in people receiving hemodialysis. Researchers will enroll 75 …

This study tests whether a smartphone app called SOLOMIYA is helpful and easy to use for people living under the stress of war in Ukraine. About 80 adults with mild to moderate depression or sleep problems will use the app for a few weeks. The app provides relaxation exercises, m…

This study tests an AI-driven home exercise program for adults aged 60 and older with chronic insomnia. The program uses a smart mirror for real-time exercise guidance and a wearable device to track sleep. Researchers will measure sleep quality, physical fitness, and body composi…

This small pilot study will test whether an 8-week group mindfulness program can reduce stress, anxiety, depression, and insomnia in parents caring for children with autism or ADHD. Thirty Chinese caregivers will attend weekly sessions and complete surveys before and after the pr…

This study tests a multidisciplinary program for adults with chronic back pain. Participants will attend group sessions on pain education, healthy habits, and emotional coping, plus do therapeutic exercises. The goal is to see if the program improves physical function, reduces fe…

This study tests whether a supplement called FibroThol (containing 2-Aticyto Complex and D-ribose) can help reduce pain and other symptoms in people with fibromyalgia. About 200 adults aged 18 to 65 who have had fibromyalgia for at least a year and are already on standard medicat…

This phase 2 trial tests whether a traditional Chinese herbal paste called Ning Shen Dan Xiang Gao Fang, made with donkey-hide gelatin, can improve sleep in adults with chronic insomnia. Sixty participants will take the paste or a placebo twice daily for 8 weeks. Researchers will…

This study tests whether teaching older adults (60+) about healthy sleep habits can reduce insomnia. Over 6 weeks, participants attend two face-to-face sessions and get regular phone follow-ups. The goal is to see if this behavioral approach improves sleep quality without medicat…

This pilot study tests whether a short, four-session cognitive behavioural therapy for insomnia (CBT-I) group, led by trained laypersons, can improve sleep quality in older adults in Hong Kong. Fifty participants aged 45 and older with mild depression and sleep problems will eith…

This study tests whether electroacupuncture (a type of acupuncture with mild electrical pulses) can reduce a group of common symptoms—pain, tiredness, sleep problems, anxiety, depression, and memory fogginess—in breast cancer survivors who are on hormone therapy. About 228 women …

This study tests if tiny thumbtack needles placed on the skin can help women going through menopause sleep better. 198 women with chronic insomnia will either get real or fake needles for 4 weeks. The goal is to see if this simple, low-risk treatment improves sleep quality and re…

This study will test whether an 18-day spa therapy program can reduce insomnia severity. About 270 adults who are already scheduled for spa treatment will fill out questionnaires about their sleep, fatigue, pain, and mood before, right after, and two months after the program. The…

This study looks at whether listening to music can help lower anxiety and improve sleep in people who have had a heart attack and are spending their first night in a special heart unit. About 64 adults will take part. They will listen to music and then use eye masks and earplugs …

This study looks at whether racism-related stress affects how well a digital cognitive behavioral therapy program (Sleepio) works for insomnia in Black adults. One hundred participants will use the app for 6-10 weeks while researchers track their sleep and stress levels. The goal…

This study looks at whether laughter yoga can help menopausal women feel better. Researchers will split 80 women into two groups: one does laughter yoga for 8 sessions, the other does nothing new. They will check if the yoga group has fewer menopause symptoms, better sleep, and a…

This study tests whether wearing blue-blocking glasses at night can help teenagers (ages 12-18) with insomnia or delayed sleep phase disorder who are already receiving psychiatric care. Forty participants will wear the glasses or use real darkness for one week. The goal is to see…

This study tests whether a single session of sleep hygiene education can improve sleep quality and reduce pain in 100 adults with migraine or chronic lower back pain. Participants will learn healthy sleep habits and follow them for four weeks, tracking changes through questionnai…

This study tests whether daily mindfulness exercises—like breathing and meditation—can reduce anxiety, depression, and poor sleep in women going through early menopause. Twenty women in Turkey will be split into two groups: one does mindfulness training for an hour, six days a we…

This Phase II trial tests a new drug called APSTZD for people with chronic insomnia. About 222 adults aged 18-64 will receive either APSTZD, an active comparator (Stilnox CR), or a placebo. The main goal is to see if APSTZD reduces time awake after falling asleep, measured by ove…

This study tests whether teaching parents a consistent, calming bedtime routine can improve sleep in infants and toddlers diagnosed with behavioral insomnia. Thirty children aged 0-3 years will wear a watch-like device to track sleep quality, and parents will report on sleep patt…

This study tests whether combining relaxation exercises with listening to a specific Quran chapter (Surah Ar-Rahman) can reduce anxiety and improve sleep in people undergoing kidney dialysis. 76 adult Muslim patients will be split into two groups: one doing the relaxation and Qur…

This pilot study tests whether a smartphone app called SleepFix, combined with support from a psychologist, can help young people aged 16-24 with insomnia. The app uses sleep restriction therapy to reset sleep patterns. The trial will check if the approach is practical and accept…

This study tests whether taking a specific probiotic (Lactobacillus rhamnosus GG) with a special form of vitamin B2 for 12 weeks can improve memory and thinking in adults over 65 who have mild memory problems. Researchers will measure changes in cognitive tests and brain activity…

This study tests whether a program that strengthens the quadriceps and calf muscles can improve walking, reduce pain, and enhance sleep in people with knee osteoarthritis. About 52 adults aged 40-60 with moderate knee arthritis will be randomly assigned to either the exercise pro…

This study tests a safe, non-invasive therapy that uses gentle pressure on the arms to improve sleep and mood in people who have had a stroke and suffer from insomnia. The treatment, called remote ischemic adaptation, aims to help the brain recover by briefly restricting and rest…

This study tests a sleep therapy called SleepSMART for older veterans who have both insomnia and mild cognitive impairment (MCI). The therapy adapts standard insomnia treatment with extra memory and learning support. Researchers will compare SleepSMART to standard therapy in 150 …

This study tests whether reducing blue light exposure in the evening—using amber-tinted glasses or smart lightbulbs—can help children ages 5 to 6 fall asleep faster. Sixty children with sleep difficulties will be randomly assigned to one of three light-reducing strategies for two…

This study tests whether short, controlled sessions of low-oxygen breathing (intermittent hypoxia) can improve sleep in people with primary insomnia. Thirty adults aged 18 to 60 who are not taking sleep medications will be randomly assigned to receive either the real low-oxygen t…

This study tests whether facial acupuncture and scraping can help people with insomnia sleep better. 82 participants aged 16-30 will receive treatments twice a week for four weeks. Researchers will measure sleep quality and other symptoms to see if this traditional Chinese medici…

This pilot study will test whether a special form of kava (AB-free kava) can improve mobility and physical function in adults over 70 who have mild sleep problems and are somewhat inactive. Forty participants will take either kava capsules or a placebo daily for a period, and res…

This study will test a robotic device called BackHug that delivers deep back massages to 30 adults with mild-to-moderate Parkinson's disease. The goal is to see if it improves walking, balance, back pain, and sleep quality. Participants will receive 40-minute sessions over a set …

This study tests whether EMDR group therapy can help adults who experienced the April 2025 Silivri earthquake in Turkey. Forty participants will be randomly assigned to either the therapy group or a waitlist. Researchers will measure changes in PTSD, depression, anxiety, sleep qu…

This study looks at whether using a pillow placed behind the shoulder after rotator cuff repair surgery can lower pain and improve sleep. About 126 adults aged 40 to 70 will choose whether to use the pillow or not. Their pain, sleep quality, and shoulder function will be checked …

This study looks at whether teaching people with rotator cuff syndrome the best sleeping positions can improve their sleep quality while they undergo physical therapy. Researchers will compare two groups: one getting standard physical therapy, and another getting physical therapy…

This study tests whether a small, home-use ear stimulation device can improve sleep and reduce stress in health sciences students who have trouble sleeping. Sixty students will either receive active stimulation or a placebo for three weeks. The goal is to see if this easy, non-in…

This study tests a special type of acupuncture—dense cranial electroacupuncture plus body acupuncture—in 148 teens aged 15-22 with mild to moderate anxiety or depression. Participants receive treatment twice a week for 8 weeks, and researchers measure changes in anxiety, depressi…

This study tests whether a warm foot bath on the night of abdominal surgery can reduce pain, improve sleep, and increase comfort. Around 96 adults will be randomly assigned to receive a foot bath or standard care. Researchers will measure pain levels and sleep quality using simpl…

This study tests whether a special type of acupressure—timed to the body's natural daily rhythms—can improve sleep in nursing home residents aged 60 and older. Eighty participants will receive either real or fake acupressure twice a day for four weeks. Researchers will measure sl…

This pilot study will test whether a smartphone app that teaches cognitive behavioral therapy for insomnia (CBTI) can improve sleep in 144 active-duty service members. Participants will use the app for five weeks, and researchers will measure changes in insomnia severity, depress…

This study looks at whether taking magnesium by mouth or soaking feet in a magnesium solution can help colorectal cancer patients who are on chemotherapy. The goal is to see if these simple treatments can reduce nerve damage (pain, tingling) and improve sleep quality. About 75 ad…

This study tests whether daridorexant, a recently FDA-approved sleep medication, can improve sleep quality and daytime alertness in smokers who struggle with insomnia during quit attempts. About 44 adult smokers who smoke at least 10 cigarettes daily will take the drug or a place…

This study tests whether Emotional Freedom Techniques (EFT), a tapping-based therapy, can lower stress, anxiety, and improve sleep in nursing students. 105 students will be randomly assigned to either EFT or a placebo. The main goal is to see if stress levels drop after 8 weeks. …

This study tests a high-tech version of cognitive behavioral therapy for insomnia (CBT-I) in adults aged 65 and older. It uses smart devices, sensors, and artificial intelligence to personalize sleep coaching at home. Researchers will compare it to simpler digital sleep programs …

This study will test a smartphone app called CONEMO in over 12,000 adults visiting primary care clinics. The app uses cognitive behavioral therapy techniques to help reduce symptoms of depression, anxiety, and insomnia. Participants will use the app on their own phones or tablets…

This study tests whether a special 40 Hz flickering light, used for 30 minutes each night for a week, can improve insomnia in people with Parkinson's disease. Thirty participants will be randomly assigned to receive either the 40 Hz light or a control light. The main goal is to s…

This study looks at whether adding stress management and sleep education to standard physiotherapy can help people with temporomandibular disorders (TMD). TMD causes jaw pain, teeth grinding, and sleep problems. Forty adults with TMD will receive either physiotherapy alone or phy…

This study tests a nurse-led program to reduce stress and improve sleep for patients in the intensive care unit (ICU). The program includes lowering noise, dimming lights at night, and grouping care tasks to avoid waking patients. About 68 awake adults will either receive this pr…

This study tests a non-invasive treatment called remote ischemic conditioning (RIC) for sleep problems in people with Parkinson's disease. For 7 days, 48 participants will receive either active RIC (using a blood pressure cuff to briefly restrict arm blood flow) or a sham version…

This study tests whether teaching COPD patients how to use their inhalers correctly, via video calls with a nurse, can improve their sleep quality. Researchers will compare sleep scores between those who get the education and those who don't. Sixty adults who already use inhaled …

This study tests a drug-free approach for restless leg syndrome (RLS) in people with type 2 diabetes. 42 adults aged 50-65 will receive either vibration, near-infrared light, or both, plus stretching, for 4 weeks. Researchers will measure changes in pain, sleep quality, and RLS s…

This study tests whether Compound Ciwujia Granules, a traditional Chinese herbal medicine, can improve sleep in people with chronic insomnia. 1,200 adults aged 40-75 will take either the herb, a standard sleep drug (estazolam), or both for 4 weeks. Researchers will measure sleep …

This study tests whether a smartphone app can improve sleep for new parents struggling with insomnia. About 250 first-time parents with babies aged 4-12 months will use the Headspace Health Sleep Program for 18 days. The app combines sleep tracking, cognitive behavioral therapy, …

This study will test whether using an automatic baby swing helps newborns in the neonatal intensive care unit (NICU) sleep better, feel more comfortable, and have stable heart rate, breathing, and temperature. The study will include 40 healthy newborns born between 35 and 42 week…

This study tests a smartphone app called BELL-001 that plays personalized sounds in sync with your breathing to help you relax and fall asleep. 114 adults with insomnia will use the app or a sham version nightly for 4 weeks. Researchers will measure changes in sleep quality and d…

This study looks at whether doing foot and ankle exercises at home can help people with diabetic nerve pain feel better. The exercises are done twice a day, three days a week, for eight weeks. Researchers will measure pain, sleep quality, and depression in 70 adults with diabetic…

This real-world study will test whether Ciwujia Capsules or Compound Ciwujia Granules can improve sleep quality and reduce insomnia severity in 40,000 adults aged 18-75. Participants will take the herbal supplement for 8 weeks, and researchers will measure changes in sleep scores…

This study tests whether a mobile app called SleepQ can reduce insomnia symptoms in adults. The app provides a 12-week digital cognitive behavioral therapy program, including sleep scheduling and relaxation techniques. Eighty participants will be randomly assigned to use the app …

This study tests a smartphone app called GoodShleep that gives personalized sleep and circadian tips in real time. It includes a wearable to track sleep and activity, plus mood check-ins. Researchers will first optimize the app with 77 adults in Hong Kong who have sleep or circad…

This study tests a smartphone app called GoodShleep+ that gives personalized, in-the-moment suggestions to help people with sleep and circadian problems. About 80 adults in Hong Kong will either use the app for 8 weeks or continue their usual care. The goal is to see if the app i…

This study looks at whether eating special healthy cookies high in linoleic acid (a type of fat) for 8 weeks can improve sleep quality in overweight adults who have trouble sleeping. Researchers will measure sleep changes, blood fat levels, and how well people stick to eating the…

This study tests whether practicing tai chi for 8 weeks can improve sleep quality in adults aged 40 to 69 with mild to moderate chronic insomnia. Sixty participants will be randomly assigned to either a tai chi group or a walking group. The goal is to see if tai chi offers a safe…

This study tests whether a structured eye exercise program can improve sleep quality in older adults (65+) living in a nursing home. Participants will do eye exercises three times a week for four weeks, guided by a researcher. The goal is to see if these exercises lead to better …

This study tests whether a smartphone app that guides patients through acupressure can reduce fatigue, itching, and improve sleep in people on hemodialysis. About 70 adults who have been on dialysis for at least three months will be randomly assigned to use the app daily for four…

This study looks at whether a regular, low-intensity exercise program can improve sleep quality in people aged 65 and older. Eighteen participants will do safe movements like chair exercises, balance work, and stretching. Researchers will measure sleep changes using questionnaire…

This study looks at whether doing moderate resistance exercises in the morning can improve sleep quality in young adults aged 18-35. Over 8 weeks, 64 participants with different sleep patterns (morning or evening types) will follow an online exercise program. Researchers will mea…

This study tests whether a gentle, non-invasive brain stimulation technique called transcranial alternating current stimulation (tACS) can improve sleep and reduce anxiety in adults over 60 who have chronic insomnia. Sixty participants will receive tACS sessions, and researchers …

This study tests whether a brief behavioral therapy for insomnia (BBTI) can improve sleep in 58 bereaved adults who have trouble sleeping. Participants will either receive BBTI or sleep hygiene education. The study also looks at whether better sleep eases symptoms of complicated …

This study tests whether a type of talking therapy called Cognitive Behavioral Therapy for Insomnia (CBTi) can improve sleep and reduce mental distress in young people aged 12-24 in Hong Kong who have moderate mental health concerns. Participants will attend six weekly group sess…

This study looks at whether Benson relaxation exercises can improve sleep quality in people with lung cancer who are staying in the hospital. About 60 patients will be randomly assigned to do the exercises or not. The goal is to see if this simple, drug-free technique helps them …

This study tests whether a dietary supplement can help people with poor sleep quality fall asleep faster and improve their overall sleep. About 70 adults aged 24-65 with mild sleep issues will take either the supplement or a placebo, and their sleep will be tracked with a wrist m…

This study looks at whether listening to music during dialysis sessions can help reduce fatigue, improve sleep quality, and boost mental well-being. Sixty adults on hemodialysis will receive 30 minutes of music therapy after the second hour of each session for four weeks. Researc…

This study tests a gentle exercise method called global postural reeducation in 30 housewives aged 25-40 who have had low back pain for over 3 months. The goal is to see if it can reduce pain, lower stress, and improve sleep quality. Unlike painkillers, this approach focuses on r…

This study tests whether inhaling agarwood essential oil while sleeping can reduce fatigue and improve sleep quality in hospital staff. About 78 participants will use either an agarwood sachet or a placebo (almond oil) near their bed for one week. Researchers will measure changes…

This study will test whether taking a break from digital devices and social media can help reduce depression, anxiety, stress, and improve sleep quality in young adults. One hundred participants who use social media at least 8 hours a day will be randomly assigned to a digital de…

This study tests whether low-dose laser acupuncture (LLA) can safely improve sleep in 120 adults with major depressive disorder and insomnia. Participants will receive either real or sham laser acupuncture five times a week for six weeks, while continuing their usual depression m…

This study tests whether a 4-week program combining ergonomic training with exercise can reduce pain, improve sleep quality, and lower anxiety in nursing students. Sixty participants will be randomly assigned to either the program or standard curriculum. The goal is to see if the…

This study looks at whether university students who exercise regularly have better cognitive awareness, body awareness, and sleep quality compared to those who are sedentary. Researchers will survey 140 students aged 18-25, grouping them by their physical activity levels. No drug…

This study follows adults waiting for a liver transplant to see how their sleep quality changes from before surgery to six months after. Researchers use questionnaires to measure sleep, anxiety, and other factors. The goal is to understand what influences sleep problems in these …

This observational study will follow 200 women aged 45 to 60 to understand how muscle strength, bone density, body composition, physical activity, sleep, mood, and menopause symptoms relate to overall functional health. Participants will undergo simple strength tests, bone scans,…

This study follows 100 new nurses over time, using non-invasive sleep monitors and questionnaires to track sleep quality, stress, and burnout. Researchers will use AI to see if sleep data can predict which nurses are at risk of burnout or leaving their jobs. No treatments are giv…

This study follows 25 adolescent girls with anorexia nervosa over 12 months of psychiatric treatment. Researchers will measure sleep patterns, inflammation, hormones, and quality of life at the start and after one year. The goal is to see how these factors change with treatment a…

This study looks at how stress levels, sleep quality, and teeth grinding (bruxism) together affect gum disease in adults aged 30-45. Researchers will compare two groups of people with gum disease: those who grind their teeth and those who do not. The goal is to understand how the…

This study will use wearable devices like heart rate monitors and sleep trackers to see how financial stress and news affect your body. Researchers will follow 2,500 adults remotely, collecting data on heart rate, sleep, and stress levels. The goal is to create AI tools that can …

This study will examine 600 men aged 35-59 in Uzbekistan to find out which physical, lifestyle, and emotional factors are linked to low testosterone. Participants will have blood tests, physical measurements, and complete questionnaires. The goal is to create a model that helps d…

This study looks at how internet addiction affects sleep quality and academic performance in medical students at Sohag University. Researchers will survey 499 students using standard tests for internet addiction, sleep quality, and grades. The goal is to understand the problem, n…

This study will test a new wearable device that monitors your body's internal clock (circadian rhythm) by tracking signals like heart rate and movement. Researchers will compare the device's readings to standard saliva tests in 30 adults who are either healthy, have sleep apnea, …

This study will track sleep patterns in 20 people before and after reverse shoulder replacement surgery. Participants will wear a MotionWatch 8 sleep tracker for a week before surgery and again 6 months after. The goal is to see if better sleep is linked to better recovery and sh…

This study aims to find out which daily habits and surroundings are linked to poor sleep in people with lupus. Researchers will survey 250 adults with lupus from different parts of Spain about their sleep, physical activity, screen time, and bedroom environment. The goal is to id…

This study looks at how physical activity levels are linked to posture, sleep quality, depression, and muscle or joint pain in health science professors and researchers at Istanbul Aydin University. About 73 academics aged 23 to 65 will fill out questionnaires. The goal is to und…

This study uses a large Korean health database to see if developing insomnia after a heart attack (treated with stents or bypass surgery) is linked to worse long-term outcomes like death, another heart attack, or stroke. Researchers will compare patients who take insomnia medicat…

This pilot study will test whether a drug called dexmedetomidine can reduce activity in a brain region (the locus coeruleus) that may be too active during sleep in people with insomnia. Fifteen adults with insomnia will receive either the drug or a placebo before bed in a crossov…

This study looks at whether a short sleep education program can improve sleep habits and quality in health sciences students. About 100 students will attend four weekly 40-minute classes covering bedtime routines, caffeine limits, and stress management. Researchers will measure s…

This study will use an overnight sleep test (polysomnography) to measure breathing problems during sleep in 30 adults with systemic sclerosis (scleroderma). The goal is to find out how common sleep-disordered breathing is in this group. No treatment is given—this is purely an obs…