Could a sleep drug curb heavy drinking? new trial investigates

NCT ID NCT07701928

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This trial tests whether the sleep medication daridorexant can help people with alcohol use disorder and insomnia drink less. Participants take either daridorexant or a placebo nightly for 12 weeks, along with brief counseling. The study tracks alcohol use through self-reports and urine tests, and measures sleep using an EEG headband. Results will show if improving sleep can also reduce heavy drinking.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
daridorexant, a sleep medication taken as a 50 mg tablet once daily at night
What this could lead to
If successful, this could point toward a new treatment that improves sleep and reduces heavy drinking in people with alcohol use disorder.
What could go wrong
This is a mid-stage trial with 205 participants, so results may not apply to everyone. The drug may not reduce drinking more than placebo, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • WSU Research Clinic

    Spokane, Washington, 99202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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