Could a sleep drug fix chronic insomnia? new trial aims to find out

NCT ID NCT07255027

Not yet recruiting Disease control Sponsor: Beijing Tiantan Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a drug called dexmedetomidine, given through an IV to induce sleep, can help people with severe insomnia that hasn't improved with other treatments. 180 adults aged 18-65 will receive either the drug plus standard oral medication or standard medication alone. The goal is to see if this approach improves deep sleep and provides lasting relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dexmedetomidine (a sedative drug given intravenously) plus standard oral sleep medication
What this could lead to: If it works, this could offer a new treatment option for people with severe, hard-to-treat insomnia that hasn't improved with standard therapies.
What could go wrong: This is an early-stage study with only 180 participants, so results may not apply to everyone. The treatment involves sedation and carries risks like low blood pressure or slow heart rate, and long-term benefits are still unclear.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

insomnia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INSOMNIA

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