Can cannabis compounds help cancer patients sleep better?

NCT ID NCT07565974

Not yet recruiting Symptom relief Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether THC (with or without CBD) can improve sleep in people with solid organ cancer who have insomnia. About 69 participants will receive either THC, a THC/CBD mix, or a placebo as a liquid under the tongue. The goal is to see if these cannabis-based compounds help with sleep quality and overall well-being.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: THC and THC/CBD (cannabinoids)
What this could lead to: If it works, this could provide a new option for managing insomnia in cancer patients, improving sleep quality and quality of life.
What could go wrong: This is a small, early-phase pilot study. The results may not apply to all cancer patients, and cannabinoids can cause side effects like dizziness or mood changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer insomnia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INSOMNIA MALIGNANT SOLID NEOPLASM

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Contact Email: •••••@•••••

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