Brain training may tame migraines without drugs

NCT ID NCT07661888

Not yet recruiting Symptom relief Sponsor: University of Salamanca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether neurofeedback—a type of brainwave training—can help adults with episodic migraine have fewer and less severe headaches. Participants will undergo 60 sessions over 12 weeks, learning to regulate their brain activity through real-time feedback. The goal is to see if this non-drug approach can reduce migraine frequency, severity, and reliance on medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Neurofeedback (EEG-based brainwave training and blood volume pulse biofeedback)
What this could lead to: If effective, neurofeedback could offer a drug-free way to reduce migraine attacks and improve quality of life for people with episodic migraine.
What could go wrong: This is a small, early-stage trial with 66 participants, and results may not apply to everyone. The intensive 60-session schedule may be hard to maintain, and benefits may not last long-term.

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Conditions

The condition(s) this trial relates to.

insomnia migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EPISODIC MIGRAINE

Contacts and locations

Locations

University Hospital of Salamanca

Salamanca, Salamanca, 37007, Spain

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