Could two old drugs beat one for migraine prevention?
NCT ID NCT07655700
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests whether taking two inexpensive migraine prevention drugs together works better than taking either one alone. Adults aged 18 to 55 who have at least four migraines per month will receive propranolol, flunarizine, or both for 12 weeks. The goal is to see which approach reduces monthly migraine days most effectively and safely.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
propranolol and flunarizine (alone or combined)
What this could lead to
If the combination works better, it could offer a more effective, affordable option for preventing frequent migraines without needing expensive new drugs.
What could go wrong
This is a single-center, open-label trial, so results may not apply broadly. Side effects from either drug or the combination could limit use, and the 12-week duration may not reflect long-term benefits.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Chittagong Medical College
Chittagong, 4203, Bangladesh
Contact Phone: •••-•••-•••• Email: •••••@•••••