BREAST CANCER

This study tested a vaccine made from a patient's own immune cells, trained to attack HER-2 positive breast cancer cells. The goal was to see if it is safe and can boost the immune system to prevent cancer from returning in 15 women with high-risk or recurrent breast cancer who h…

This study looked at whether montelukast, an asthma drug, can reduce heart damage caused by doxorubicin chemotherapy in breast cancer patients. 50 adults with breast cancer were randomly assigned to receive either montelukast or a placebo alongside their treatment. Researchers me…

This study tested a new drug called CBX-12 in 69 adults with advanced solid tumors (like ovarian, lung, breast, or colon cancer) that had stopped responding to standard treatments. The goal was to find a safe dose and see if the drug could shrink tumors. The study was completed, …

This study tested whether adding a low-dose chemotherapy drug (capecitabine) to a standard hormone therapy (aromatase inhibitor) helps women with a common type of advanced breast cancer live longer without their disease getting worse. The trial included 263 women who had not rece…

This study tested a personalized nutrition and exercise counseling program for breast cancer survivors who were overweight. The program included both in-person and phone sessions to make it easier to participate. The main goals were to see if participants could lose 10% of their …

This study tested whether the chemotherapy drug cisplatin works better than a standard combination (doxorubicin and cyclophosphamide) for women with newly diagnosed breast cancer who carry a BRCA gene mutation. 118 women participated, receiving one of the two treatments before su…

This study tested whether adding enzalutamide to the hormone therapy exemestane helps control advanced breast cancer that is hormone receptor-positive and HER2-normal. About 247 postmenopausal women who had already tried some treatments took part. The main goal was to see if the …

This phase 3 trial tested whether adding the antibiotic moxifloxacin to standard chemotherapy helps prevent breast cancer from returning after surgery. 559 people with operable breast cancer took part. The study compared disease-free survival between those who got moxifloxacin an…

This study tested whether a combination of triptorelin and exemestane works better than triptorelin and tamoxifen in premenopausal women with hormone-sensitive breast cancer. Over 2,600 women who had surgery to remove their cancer took part. The goal was to see which treatment he…

This study tested a new way to give radiation to people with early-stage, low-risk breast cancer. Instead of many sessions, only three doses were given directly to the tumor area. The goal was to see if this shorter treatment is safe and works well. 77 participants completed the …

This study tested whether adding a drug called ganetespib to the standard hormone therapy fulvestrant helps people with a certain type of advanced breast cancer. The cancer was hormone receptor-positive and had stopped responding to hormone therapy. Fifty adults took part. The go…

This study looked at whether adding a nurse trained in diabetes care to the treatment team helps breast cancer patients with diabetes or prediabetes manage their blood sugar during cancer therapy. 74 patients were split into two groups: one worked with the nurse, the other did no…

This study tested an experimental drug called BB-1701 in 56 people with advanced breast cancer that had not responded to prior treatments. The drug targets a protein called HER2 on cancer cells to deliver chemotherapy directly to the tumor. The goal was to find the best dose and …

This study tested a combination of two chemotherapy drugs (epirubicin and docetaxel) at increasing doses, along with a drug to help the immune system recover (pegfilgrastim), in 93 women with locally advanced or inflammatory breast cancer. The goal was to see how well the treatme…

This study tested whether adding a new drug called darsilide to standard hormone therapy (exemestane and goserelin) could shrink tumors more effectively in premenopausal women with a common type of breast cancer (HR positive, HER2 negative). The 119 participants had already recei…

This study tested a new drug called LY3484356 in 87 postmenopausal women with early-stage, hormone-positive breast cancer. The drug was given for a short time before surgery to see if it is safe and how it affects the cancer. The goal was to measure changes in estrogen receptors …

This study tested a new treatment combination for people with advanced breast cancer that has stopped responding to standard therapies. The treatment uses a personalized vaccine (SV-BR-1-GM) plus an immunotherapy drug (retifanlimab) to help the immune system fight the cancer. The…

This study looked at 126 women with advanced, hormone-sensitive breast cancer. It tested whether adding the cholesterol-lowering drug atorvastatin to standard hormone therapy (letrozole, fulvestrant, or aromatase inhibitors) could improve cancer control and delay progression. The…

This study tracked over 1,100 breast cancer patients who received a precise, one-time radiation boost directly to the tumor site during surgery, followed by standard radiation therapy. The goal was to see how well this approach controls cancer and what side effects occur. Results…

This study tested a combination of three drugs (paclitaxel, trastuzumab, and pertuzumab) given before surgery to 23 people with a rare and aggressive type of breast cancer called inflammatory breast cancer. The goal was to see if the treatment could eliminate all signs of cancer …

This study looked at 215 breast cancer patients who had chemotherapy. It compared the usual vitamin D supplement dose with a dose adjusted to each patient's vitamin D level. The goal was to see which approach better normalizes vitamin D levels after 6 months.

This study tested whether combining the drug atezolizumab with a precise type of radiation (stereotactic radiosurgery) could help control triple-negative breast cancer that has spread to the brain. Six participants with stage IV breast cancer took part. The goal was to see how lo…

This study tested a specific chemotherapy combination given before surgery in 29 people with triple-negative breast cancer, a fast-growing type. The goal was to see if the treatment could completely clear all cancer from the breast and nearby lymph nodes. Researchers measured how…

This study tested an experimental drug called ARV-471, alone or with another drug (palbociclib), in 217 adults with a common type of advanced breast cancer (ER+/HER2-) that had stopped responding to prior hormone therapy and chemotherapy. The main goals were to check safety and s…

This study tested a new drug called giredestrant, alone or with triptorelin, against a standard treatment (anastrozole plus triptorelin) in 231 premenopausal women with early-stage, hormone-sensitive breast cancer. The goal was to see how well these treatments slow tumor growth b…

This early-stage study tested a new drug called SNB-101 in 21 people with advanced solid tumors (like colorectal, breast, or lung cancer) that had stopped responding to standard treatments. The drug is a nanoparticle version of a chemotherapy agent, given through an IV, and the m…

This early-phase trial tested an experimental pill called ART4215 in 93 people with advanced or metastatic solid tumors (including breast cancer). The main goals were to find a safe dose and check for side effects when given alone or with other cancer drugs. The study is now comp…

This study tested whether adding the drug nintedanib to standard chemotherapy (docetaxel) helps control advanced breast cancer longer. 51 adults with HER2-negative breast cancer that had spread or returned took part. The main goal was to see if the combination kept the cancer fro…

This study looked at whether a shorter course of radiation therapy is safe and effective for women with breast cancer that had spread to their lymph nodes. 108 women who had already had surgery took part. The main goal was to track side effects like arm swelling, shoulder stiffne…

This study looked at how often bone marrow suppression (a serious side effect) happens in people with BRCA-mutated, HER2-negative breast cancer who are at high risk of the cancer coming back. Participants took LYNPARZA tablets after surgery to help keep the cancer away. The main …

This study tested whether adding the experimental drug PF-07220060 to the standard hormone therapy letrozole works better than letrozole alone in postmenopausal women with a common type of breast cancer (HR+/HER2-). About 121 women who had not yet received treatment took the pill…

This study looked at how well the drug ribociclib works in real-world settings for Indian women with a common type of advanced breast cancer (HR+, HER2-). Researchers reviewed medical records from 335 patients across 18 hospitals in India. The goal was to see how long the drug ke…

This study tested whether adding the immunotherapy drug pembrolizumab to standard chemotherapy (carboplatin) helps control breast cancer that has returned on the chest wall. The trial included 76 women with either triple-negative or hormone-resistant breast cancer. Researchers me…

This study looked at whether an 8-week healthy eating and exercise program could help breast cancer survivors feel less stressed and improve their overall health. Twenty-two adults who had breast cancer took part in weekly virtual sessions. Researchers measured stress, diet, and …

This early-phase trial tested a new combination of two drugs, ARV-471 and everolimus, in 32 people with a certain type of advanced breast cancer (ER+/HER2-). The main goals were to find the safest dose and check for side effects. The study is now complete, and results will help g…

This study tested whether a drug called T-DM1 causes fewer side effects than the standard treatment of paclitaxel plus trastuzumab in people with stage I HER2-positive breast cancer. About 500 participants were randomly assigned to one of the two treatments. The researchers also …

This early-phase study tested whether the heart medication carvedilol could safely prevent heart damage in breast cancer patients receiving chemotherapy with doxorubicin and/or trastuzumab. Researchers assigned 68 women to either usual care or carvedilol based on their risk of he…

This study tested the drug neratinib, alone or with other medicines, in 140 people with HER2-positive breast cancer that had spread to the brain. The goal was to see if the treatment could shrink or stabilize brain tumors. Researchers also looked at how previous treatments affect…

This study tested a cancer vaccine called ETBX-011 in 43 people with advanced colorectal, lung, breast, or prostate cancers that make a protein called CEA. The vaccine uses a modified virus to teach the immune system to find and attack CEA-making cancer cells. The main goals were…

This study tested a new way to rebuild the breast after preventive mastectomy in women at high genetic risk for breast cancer. Instead of a scar on the breast and cutting the chest muscle, surgeons used a single-port endoscope through a small incision in the armpit to place the i…

This large phase 3 study tested whether adding the drug pertuzumab to standard chemotherapy and trastuzumab could help prevent breast cancer from returning in people with operable HER2-positive breast cancer. About 4,800 participants were randomly assigned to receive either pertu…

This study tested whether metformin, a common diabetes medicine, can reduce the thickening of the uterine lining caused by tamoxifen in postmenopausal women with estrogen-positive breast cancer. Sixty women who had been taking tamoxifen for at least a year were randomly assigned …

This study tested a new chemotherapy drug called WH002 against the standard drug paclitaxel in 40 women with HER2-negative breast cancer. Both drugs were given before surgery, followed by two other chemotherapy drugs. The main goal was to check safety and side effects, and also t…

This early-phase study tested a personalized vaccine made from a patient's own immune cells, designed to target HER2-positive breast cancer. 31 adults with stage II or III breast cancer received the vaccine alongside standard chemotherapy before surgery. The goal was to see if th…

This study tested a combination of two drugs—an immunotherapy (pembrolizumab) and a PARP inhibitor (olaparib)—in 14 people with advanced breast cancer that has a BRCA mutation or similar DNA repair problem. The goal was to see if the combo could shrink or stabilize tumors. The ca…

This study tested a new drug, alpelisib, combined with hormone therapy in 383 people with advanced breast cancer that has a specific genetic change (PIK3CA mutation). The goal was to see if the combination could stop the cancer from growing for at least 6 months. Results showed t…

This study tested a surgery called nipple-sparing mastectomy for people with breast cancer. The goal was to see if removing the breast tissue but keeping the nipple and skin is safe and leads to low cancer return rates. 450 participants were followed for 5 years after surgery. Th…

This early-phase study tested a personalized vaccine made from yeast that is designed to teach the immune system to recognize and attack leftover cancer cells. It included 5 adults with different cancers who had already completed treatment aimed at curing their disease. The goal …

This study observed 178 Chinese patients with HER2-positive advanced breast cancer who received the drug T-DM1 after earlier treatments failed. Researchers tracked side effects and how long the drug kept the cancer from growing in real-world settings. The goal was to confirm the …

This study tested a new drug, trastuzumab deruxtecan, against standard treatments in 608 people with advanced HER2-positive breast cancer that had already been treated with T-DM1. The goal was to see if the new drug could slow cancer growth or improve survival. Results help docto…

This study tested whether adding the drug samuraciclib to standard hormone therapy (fulvestrant) works better than fulvestrant alone for people with a certain type of advanced breast cancer (HR-positive, HER2-negative). The trial included 60 adults whose cancer had worsened despi…

This early-phase study tested a new daily pill called JAB-3312 in 40 adults with advanced solid tumors (like lung, colorectal, or breast cancer) that had stopped responding to standard treatments. The main goals were to find the safest dose and check for side effects. Researchers…

This early-phase study tested a new approach for women with breast cancer who cannot have breast-conserving surgery. It combined a short course of high-dose radiation (Cyberknife) with standard chemotherapy drugs. The main goal was to find the safest radiation dose and see how we…

This study tested a new two-drug combination (samuraciclib and elacestrant) in 49 adults with a specific type of advanced breast cancer (HR+/HER2-). The goal was to see if the combination is safe and can slow down the cancer's growth. Participants had already tried other treatmen…

This pilot study tested a multi-disciplinary health behavior program for 50 breast cancer survivors to reduce their risk of heart disease after cancer treatment. Participants learned about exercise, diet, and other healthy habits. The study measured changes in walking distance an…

This study observed 175 adults with HR+/HER2- advanced or metastatic breast cancer in the Middle East who received ribociclib plus hormone therapy. Researchers tracked side effects and how long the cancer stayed under control. The goal was to see how well this treatment works in …

This study looked at 720 women with early-stage breast cancer who had surgery to remove the tumor. They were split into two groups: one got standard daily radiation for several weeks, and the other got a shorter course of higher-dose radiation. The goal was to see if the shorter …

This early-phase trial tested whether combining a special type of radiation (hypofractionated radiotherapy) with two immunotherapy drugs (MEDI4736 and tremelimumab) is safe and tolerable for people with advanced melanoma, lung, breast, or pancreatic cancer that has spread. The st…

This early-phase trial tested a new drug called FS1502 in 161 adults with advanced HER2-positive solid tumors or breast cancer that had stopped responding to standard treatments. The main goals were to check the drug's safety, find the best dose, and see if it shrinks tumors. Res…

This study tested a combination of two drugs—talimogene laherparepvec (T-VEC), a virus that attacks cancer cells, and atezolizumab, an immunotherapy—in 28 women with early-stage breast cancer that still had tumor left after standard chemotherapy. The goal was to see if this combo…

This study tested a combination of three drugs (letrozole, everolimus, and TRC105) given before surgery to 15 postmenopausal women with hormone-receptor-positive, HER2-negative breast cancer. The goal was to see if the drugs were safe and could shrink tumors. The approach targets…

This study tested two different dosing schedules of the drug palbociclib combined with hormone therapy in 180 women with advanced, hormone receptor-positive breast cancer. The goal was to see if a lower daily dose (100 mg) could work as well as the standard schedule (125 mg for 2…

This study tested whether a mobile app could help people with early breast cancer follow their treatment plan and feel better. Over 500 patients were split into two groups: one used the app for reminders, tips, and communication with their care team, while the other received stan…

This study tested a reduced starting dose (400 mg) of the drug ribociclib combined with standard hormone therapy (letrozole or anastrozole) in 376 women with advanced hormone receptor-positive, HER2-negative breast cancer who had not received prior treatment for advanced disease.…

This study tested two hormone therapies, giredestrant and tamoxifen, in 92 premenopausal women with early-stage breast cancer. Participants took the drug for 15 days before surgery to see how well it slowed tumor growth. The goal was to compare the drugs' effects on cancer cell a…

This study tested whether the drug letrozole can help prevent breast cancer from returning in women who have already completed at least 5 years of tamoxifen treatment. Over 5,000 women participated, and the goal was to see if letrozole improves disease-free survival. Letrozole wo…

This study tested a pill called hetrombopag in 60 people with advanced breast cancer who had low platelets from chemotherapy. The goal was to see if the drug could safely raise platelet levels and reduce the need for platelet transfusions or chemo delays. Results will help guide …

This study tested whether adding the immunotherapy drug atezolizumab to standard chemotherapy (bevacizumab and paclitaxel) helps people with a certain type of advanced breast cancer (HR-positive, HER2-negative). The trial included 281 participants whose cancer had spread or could…

This study tested a new way to give an extra dose of radiation (a boost) to the tumor site after standard breast radiation. Instead of multiple sessions, the CyberKnife machine delivered a single high dose very precisely, aiming to reduce skin damage and improve cosmetic results.…

This study tested whether a combination of eribulin, pertuzumab, and trastuzumab works as well as the standard taxane-based combo for advanced HER2-positive breast cancer, but with better quality of life. 446 women who had not received chemotherapy for advanced disease took part.…

This study tested a new hormone therapy pill, elacestrant, against standard treatments for people with a common type of advanced breast cancer (ER+/HER2-). The trial included 478 men and women whose cancer had worsened after previous hormone therapy. The goal was to see if elaces…

This early-stage study tested a new drug called RP903 in 69 people with advanced solid tumors (like ovarian, breast, or cervical cancer) who had no other treatment options. The main goal was to check the drug's safety and find the right dose, not to cure the cancer. While some pa…

This study tested a strong chemotherapy regimen followed by a stem cell transplant for people with stage IIIB inflammatory breast cancer. The goal was to see if this approach could improve how long patients live without the cancer coming back. 41 patients took part in this phase …

This study looked at how safe and effective two targeted drugs, trastuzumab deruxtecan and sacituzumab govitecan, are for people with advanced breast cancer. Researchers reviewed medical records of 312 patients who had already tried other treatments. The goal was to see side effe…

This study tested whether adding the drug ribociclib to standard hormone therapy helps slow the growth of advanced breast cancer in Chinese women. The cancer type was hormone receptor positive and HER2 negative. 327 women took part, and the main goal was to see how long the cance…

This early-stage trial tested whether adding pulsed electromagnetic fields (PEMFs) to standard chemotherapy is safe for people with breast cancer. 14 participants received the combination before surgery. The main goal was to check for side effects, not to measure how well it work…

This study tested a non-surgical treatment for breast cancer in 21 patients aged 70 and older who could not or would not have surgery. Doctors used ultrasound to guide a needle that heats and destroys the tumor, combined with hormone therapy. The goal was to see if this approach …

This study tested whether injecting a modified herpes virus (talimogene laherparepvec) directly into breast tumors, alongside standard chemotherapy before surgery, could destroy more cancer cells in people with triple negative breast cancer. The virus is designed to infect and br…

This study looked at whether adding special ultrasound techniques (elastography and contrast-enhanced ultrasound) can more accurately detect breast cancer that has spread to the armpit lymph nodes. 180 women with breast cancer took part. The goal was to improve treatment planning…

This study looked at whether contrast-enhanced mammography (CEM) can be used instead of MRI for breast cancer screening in women at high risk. About 615 women who needed an MRI but couldn't have one (due to cost, claustrophobia, or implants) were given CEM. The goal was to see if…

This study looked at whether MRI scans can detect early signs that chemotherapy is working in women with invasive breast cancer. Sixteen women received chemotherapy before surgery, and their MRI results were reviewed by two radiologists to check if the measurements were consisten…

This study tested whether a high-resolution PET-CT scan of the removed tumor during breast-conserving surgery can help surgeons see if any cancer cells are left behind. About 206 women with early-stage breast cancer received a low-dose radioactive tracer before surgery. After the…

This study looked at whether an MRI can detect breast cancer in women who have abnormal nipple discharge but normal mammograms and ultrasounds. About 70 women took part. The goal was to see how often a normal MRI correctly ruled out cancer. The results could help avoid unnecessar…

This study tested a new blood test (liquid biopsy) to find cancer DNA in 30 women with advanced ER+/HER2- breast cancer. The goal was to see if the test could detect cancer changes in blood as accurately as standard tissue biopsies. If successful, this could allow doctors to moni…

This study tested a new, noninvasive method called SAVE that uses ultrasound to measure the stiffness of breast lumps. Researchers aimed to see if it can tell benign from malignant masses without a biopsy. The study involved 266 women with breast lesions and compared SAVE results…

This study tested an artificial intelligence (AI) tool called Carebot AI MMG to see how well it finds breast lesions and measures breast density on mammograms. Researchers compared the AI's accuracy to that of doctors using 122 mammography studies from women over 18. The goal was…

This study tested a new imaging probe (TTP-ICG) that makes cancer cells glow under a special camera. After breast cancer surgery, the probe was applied to removed tissue to see if any cancer was left at the edges (margins) and if nearby lymph nodes had cancer. The goal is to help…

This study looked at 231 women with suspicious breast lesions to see how well contrast-enhanced mammography (CESM) compares to MRI in detecting cancer. Both scans were performed and then checked against biopsy results. The goal was to find out which test is more accurate for diag…

This study tested a new handheld gamma camera (CarolIReS) to help surgeons find and remove sentinel lymph nodes in 110 women with early breast cancer or ductal carcinoma in situ. The camera was used before and during surgery to spot nodes that other methods might miss. The goal w…

This study checked if specially trained dogs can detect breast, lung, prostate, or colorectal cancer just by smelling a person's breath. Over 1,300 adults gave breath samples by breathing into a mask. The dogs then sniffed the masks and said whether they thought cancer was presen…

This study tested a new imaging technique called restriction spectrum imaging (RSI) to see if it works as well as standard breast MRI for finding breast cancer. Researchers compared the accuracy of RSI and MRI in 460 women who came for routine screening. The goal was to see if RS…

This study tested a new, low-power microwave imaging system (Wavelia #2) to see if it can find and measure breast lumps without using X-rays or radiation. 73 women with known breast abnormalities took part. The goal was to see how well the device detects both cancerous and non-ca…

This study tested a new ultrasound technique called Nonlinear Elasticity Mapping (NEM) to better tell apart benign and cancerous breast lumps. Researchers measured how breast tissue stiffness changes under pressure in 172 women. The goal was to see if this method could improve di…

This study tested whether a newer 3D mammogram (tomosynthesis) is better than standard 2D mammograms at finding advanced breast cancers in women aged 45-74. Over 26,000 women took part. The goal was to see if 3D imaging reduces the number of cancers found between screenings and c…

This study tested whether using contrast-enhanced mammography (CEM) to guide breast biopsies is more accurate than the standard stereotactic method for women with suspicious calcifications. About 184 women with BIRADS R3, R4, or R5 calcifications not linked to a mass took part. T…

This study tested whether an AI program called CadAI-B Dx helps doctors spot breast cancer on ultrasound images. Researchers looked at 797 cases (350 with cancer, 447 benign) and had 16 doctors read the images with and without the AI. The goal was to see if the AI improves accura…

This study looked at whether testing for changes in three genes (BRCA1, RASSF1A, and PTEN) in breast tissue can help doctors better diagnose breast lesions that are hard to classify. Researchers took extra tissue samples from 301 women with suspicious breast lumps and analyzed th…

This study tested whether a small, portable ultrasound device can help health workers correctly tell the difference between harmless and cancerous breast lumps in women who had a positive breast exam. 150 women with suspicious lumps were scanned by trained nurses or medical offic…

This study looked at how well MRI scans can measure the size of ductal carcinoma in situ (DCIS), a very early form of breast cancer. Forty women with DCIS had an MRI before surgery, and the MRI results were compared to the actual tumor size found during surgery. The goal was to s…

This study tested a new ultrasound technique to tell apart two main types of breast cancer (luminal and non-luminal) without needing a tissue sample. Researchers looked at blood vessel patterns in tumors from 94 women and created a scoring tool that could help doctors choose the …

This study looked at two ways to manage ovarian cancer risk in 40 women with BRCA gene mutations or strong family history. One group had their ovaries and fallopian tubes removed to prevent cancer, while the other group had regular CA-125 blood tests to catch cancer early. Resear…

This early-phase study tested whether losartan, a common blood pressure medication, could prevent early heart damage caused by radiation therapy in breast cancer patients. Five women with left-sided breast cancer took losartan during their standard radiation treatment. Researcher…

This study tested whether teaching women self-massage and stretching exercises before and after breast cancer surgery could prevent chronic pain. 143 women participated, with half receiving standard care and half also attending workshops on self-massage and stretching. The goal w…

This small pilot study tested whether a special ice plant cream could prevent hand-foot syndrome—a painful skin reaction—in 15 breast cancer patients receiving chemotherapy with doxorubicin or docetaxel. The main goal was to see if a larger, more definitive study is possible. Res…

This study tested if giving a light electrical stimulation to a specific wrist point during breast cancer surgery could help prevent nausea and vomiting after the operation. Researchers enrolled 188 women at high risk for post-operative nausea. The approach combined the wrist sti…

This study looked at whether using e-health tools—like a smartphone app or a phone call from a nurse—can help women manage pain and anxiety after a breast biopsy. About 193 women took part. The goal was to see if these tools improve care compared to standard follow-up, especially…

This study looked at whether adding ketamine to general anesthesia could lower the need for morphine and reduce pain after breast cancer surgery. About 230 adults having a mastectomy or lumpectomy took part. The goal was to see if ketamine helps control pain and limits morphine's…

This study looked at whether acupuncture can reduce hot flashes in women with hormone receptor-positive breast cancer. 84 participants were randomly assigned to receive acupuncture or standard care. The main goal was to see if acupuncture led to fewer or less severe hot flashes o…

This study tested a special surgical glue called Ifabond to see if it could reduce fluid buildup (seroma) after breast cancer surgery. 104 women having partial mastectomy with or without lymph node removal took part. The glue was applied during surgery, and doctors measured fluid…

This study tested whether a mobile app exercise program is practical and helpful for women with breast cancer undergoing chemotherapy. 32 women participated, doing guided exercises and education through the app. The goal was to see if it improves arm function, fitness, and qualit…

This study tested a new web-based dance movement therapy program for women with breast cancer. The goal was to see if it could help them better understand their emotions (alexithymia) and reduce feelings of frailty. 67 women about to start chemotherapy took part, doing online dan…

This study tested a mobile app called WeCanManage designed to help cancer survivors with disabilities manage long-term effects of their illness and treatment. Twenty adults who had breast cancer, head and neck cancer, or sarcoma participated. The goal was to see if the app was ea…

This study tested whether low-energy shock wave therapy can improve shoulder movement and reduce pain in people with axillary web syndrome, a common complication after breast cancer surgery. Twenty adults who had breast cancer surgery and developed this condition received the tre…

This study tested whether taking fat from one part of the body and moving it to a breast that was damaged by radiation can help repair the tissue. Ten women who had radiation for breast cancer took part. The goal was to see if this fat transfer could make the skin softer and less…

This study looked at whether a simple walking program can help manage fatigue in women with breast cancer who are on hormone therapy. Seventeen women participated in a 6-week program of brisk walking twice a week. The goal was to see if this could improve their energy levels and …

This study looked at 96 women having breast-conserving surgery with lymph node biopsy. It compared a nerve block (PECS) to general anesthesia to see which leads to better recovery. The goal was to find if the nerve block reduces pain and improves how patients feel after surgery.

This study tested two ways to mark non-palpable breast tumors before surgery: a tiny iodine seed versus a standard metal wire. 350 women with early breast cancer took part. The goal was to see if the seed method leads to cleaner surgical margins and less pain. Results help doctor…

This study tested a program to help young couples cope with reproductive and sexual health issues after breast or gynecologic cancer. 158 survivors and their partners participated in a videoconference intervention. The goal was to reduce distress and improve communication about t…

This study looked at whether a type of talk therapy for insomnia (CBT-I) can help breast cancer survivors take their daily hormone-blocking pills more regularly. 35 women who had trouble sleeping and often missed their medication took part. The goal was to see if improving sleep …

This study tests whether a simple writing exercise—reflecting on personal values—can help breast cancer patients manage side effects from hormone therapy and stick to their daily medication. About 250 women will be randomly assigned to either a values affirmation group or a refle…

This study looked at whether a short mindfulness program could help women with breast cancer feel less anxious and improve their quality of life around the time of surgery. 42 women participated, filling out surveys and giving finger-prick blood samples. The goal was to see if mi…

This study tested whether a single injection of a nerve block (called rhomboid intercostal block) after mastectomy can lower the chance of long-term pain. 254 women having breast cancer surgery were split into two groups: one got the nerve block, the other got no block. Researche…

This study tested whether giving the painkiller tapentadol before breast cancer surgery could lower the amount of morphine needed during and right after the operation. 70 women scheduled for breast-conserving surgery took part. The goal was to see if preemptive pain relief leads …

This study looked at whether a stress management program called Pythagorean Self-Awareness Intervention could help breast cancer patients who finished treatment (except hormone therapy). 120 women participated, and researchers measured stress, anxiety, and biological markers like…

This study looked at whether it's possible to test a program that combines different approaches to improve sexual health in women who have had breast cancer. 18 women who finished their main cancer treatment took part. The goal was to see if women would join, stay, and follow the…

This study tested a mobile health program that teaches pain coping skills to breast cancer patients in underserved areas. 180 women with persistent pain used video calls and simple technology to learn non-drug pain management techniques. The goal was to reduce pain, fatigue, and …

This study looked at whether a combination of physiotherapy techniques—including exercises, dry needling, and nerve treatments—works better than exercise alone for women with long-term shoulder pain after breast cancer treatment. 90 women who had pain for at least 6 months after …

This study tested whether a single, high-dose radiation boost (ultrahypofractionated) is as good as the usual five-dose boost after whole-breast radiation for women who had breast-conserving surgery. 132 women with early breast cancer took part. The main goal was to see if the sh…

This study tested a program called ActiveHeal EST (Engage-Sustain-Triumph) to help 30 adults with breast or prostate cancer keep doing daily activities despite challenges. Participants were diagnosed within the last year and could still be in treatment. The program aims to improv…

This study looked at whether the MyChart app can be used to track hot flash treatments in breast cancer patients. About 56 adults with breast cancer and hot flashes took part. The goal was to see if patients and doctors would use the app to report symptoms, not to test a new trea…

This study tested a hybrid (online and in-person) group education program for women who had a mastectomy. The program, based on psychodynamic nursing theory, aimed to improve how women value their bodies, reduce anxiety about their appearance, and enhance their sexual quality of …

This study tested whether standing on a gently vibrating platform for 10 minutes twice a day for 12 months could help breast cancer survivors who have muscle and joint pain from their hormone medication (aromatase inhibitors). The 72 participants were early-stage survivors who di…

This study looked at whether giving a hand massage before inserting an IV can help breast cancer patients getting chemotherapy. Sixty women took part, with half receiving a massage before the IV and half not. The researchers measured how quickly the IV was placed, how anxious pat…

This study tested a 6-week online pain management group for breast cancer survivors with ongoing pain. The goal was to see if the program helps reduce pain and is practical for larger studies. 23 survivors participated in weekly video sessions and filled out questionnaires about …

This study compared two types of breast cancer surgery: robotic nipple-sparing mastectomy with immediate reconstruction versus the standard open technique. The goal was to see which approach leads to higher patient satisfaction. About 82 women with breast cancer or high genetic r…

This study tested whether auriculotherapy (a type of ear acupuncture) can reduce joint and muscle pain caused by aromatase inhibitors, a common breast cancer hormone therapy. About 197 postmenopausal women with breast cancer who had pain for at least 3 months were randomly assign…

This study looked at whether special cognitive education activities could help breast cancer patients who were having memory, attention, and thinking problems after chemotherapy (often called 'chemobrain'). 108 patients took part, and the activities were designed to support memor…

This study tested a new way to give radiation after breast cancer surgery. Instead of many small doses, they gave fewer, larger doses (hypofractionation) with a simultaneous extra boost to the tumor area. The goal was to see if this approach causes fewer skin problems. 35 people …

This study tested a virtual reality program to help breast cancer patients who have memory or concentration problems after treatment. 23 patients used the program for 10-15 minutes each week for 6 weeks. The goal was to see if patients would stick with the program and if it could…

This study tested the safety of adding a drug called rucaparib to standard radiation therapy for women with triple negative breast cancer who still had cancer after chemotherapy and surgery. 31 women participated. The goal was to find the best dose that does not cause severe side…

This study looked at whether a supervised exercise program can help people with breast or colon cancer feel better and have a better quality of life. 78 patients either did supervised exercise for 6 weeks or received usual care. Researchers measured quality of life, fatigue, and …

This study tested a mobile app designed to help women manage lymphedema (arm swelling) and improve quality of life after breast cancer surgery. Sixty women who had breast-conserving surgery or lymph node removal used the app for education, exercises, and symptom tracking. The goa…

This study looked at whether a personalized exercise program could help improve memory, focus, and overall well-being in women treated for locally advanced breast cancer. 37 women who had chemotherapy and surgery took part. The goal was to see if exercise could reduce the mental …

This study tested whether a yoga program done at home and in class is practical for breast cancer patients on hormone therapy who have joint pain. 24 women participated, doing yoga poses daily and attending 6 sessions with a physical therapist. The goal was to see if they would s…

This study tested a food supplement made from collagen and chondroitin sulfate in 30 women with hormone-positive breast cancer who had joint pain from their hormone therapy. The goal was to see if the supplement could reduce pain and improve quality of life over 12 weeks. The app…

This study looked at whether combining an 8-week mindfulness-based stress reduction program with endurance exercise training can improve exercise capacity and quality of life in women with breast cancer. 100 women who had finished chemotherapy and were undergoing radiotherapy or …

This study tested whether giving the antidepressant mirtazapine before and after mastectomy surgery can lower pain and the need for strong painkillers like morphine. Sixty-two women scheduled for mastectomy took part. Researchers measured pain levels and morphine use in the first…

This study looked at whether a 12-week exercise program could improve body composition (like fat and muscle mass) and physical function in 62 breast cancer patients. Participants were within 2 years of diagnosis and could be receiving treatment. The goal was to see if exercise he…

This study looked at whether self-acupressure—applying gentle pressure to specific points on the body—can reduce joint pain and stiffness caused by aromatase inhibitor therapy in postmenopausal women with breast cancer. Fifty participants learned to do acupressure at home and rep…

This study tested whether using virtual reality (VR) with music during chemotherapy sessions is practical and helpful for breast cancer patients. Sixty patients were offered VR headsets to watch calming videos and listen to music while receiving treatment. The goal was to see if …

This study tested two different radiation schedules in 60 women with early breast cancer who had breast-conserving surgery. One group received a shorter, more intense course (5 sessions over 1 week), while the other received a standard shorter course (15 sessions over 3 weeks). T…

This study tested a group video app that guides breast cancer survivors through yogic breathing exercises at home. The goal was to see if the app helps reduce stress and other long-term side effects from cancer treatment. Forty women who finished radiation therapy within the past…

This study tested whether starting physical therapy and extra education before breast cancer treatment can help prevent or manage common side effects like joint pain, muscle weakness, and fatigue. 75 newly diagnosed breast cancer patients took part. Some received the extra suppor…

This study tested whether a PECS nerve block, given before surgery, could lower the amount of opioids needed and improve pain control in women undergoing breast cancer surgery. Seventy women took part, and the approach aimed to reduce pain and increase satisfaction. The results h…

This study tested whether adding two supportive drugs (loperamide for diarrhea and G-CSF for low white blood cells) could reduce severe side effects of the cancer drug sacituzumab govitecan. It involved 50 adults with advanced triple-negative or luminal breast cancer that had spr…

This study tested different nerve block injection sites to see which best reduces the need for pain medication after a double mastectomy with immediate reconstruction. Over 1,500 women participated. The goal was to find the most effective approach for managing post-surgery pain.

This study looked at whether taking Coenzyme Q10, a natural supplement, could protect nerves and reduce pain, fatigue, and tingling in women with breast cancer getting chemotherapy. Fifty women either received the supplement with their chemo or chemo alone for 12 weeks. Researche…

This study tested a relaxation program combining guided breathing (cardiac coherence) with a hypnosis session to help women with breast or gynecologic cancer feel less anxious before surgery. 53 women participated, and the program aimed to improve their recovery by reducing stres…

This study tested short, easy-to-use digital tools (called micro-interventions) designed to reduce distress and improve wellbeing in breast cancer survivors. 120 women who had been diagnosed with early-stage breast cancer in the past 5 years and had mild to moderate anxiety or de…

This study tested a special radiation method called multi-beam IMRT in 100 women with breast cancer who had implant reconstruction after mastectomy. The goal was to see if this technique could lower the chance of implant failure and other side effects compared to standard radiati…

This study tested a special light helmet for women whose hair fell out after breast cancer chemotherapy. The helmet uses low-level light therapy to try to speed up hair regrowth and improve hair thickness. 106 women who had just finished chemo used the device at home. The goal wa…

This study tested whether a technique called ischemic preconditioning, which is used in organ transplants, could reduce fat tissue damage after breast reconstruction surgery. 18 women who had breast cancer and were having delayed breast reconstruction with their own belly fat too…

This study tested a special bandage (Hydrosorb) against a water spray to manage skin burns from radiation therapy in 278 women with breast cancer. The goal was to prevent the burns from getting worse and avoid interrupting cancer treatment. The study looked at pain, skin color ch…

This study tested a smartphone-based information tool called Digi-Do for breast cancer patients about to start radiation therapy. The tool aims to help patients feel more involved and prepared before, during, and after treatment. Researchers measured changes in distress and self-…

This study tested whether using technology like smartphone apps or video calls for exercise can help women recover arm and shoulder movement after breast cancer surgery. 45 women who had surgery took part. The goal was to see if these tech-based programs work as well as in-person…

This study tested whether craniosacral therapy (CST), a gentle hands-on treatment, can improve quality of life in women who have finished curative treatment for breast cancer. 102 women were randomly assigned to receive individual CST sessions, group self-help CST training, or no…

This study tested an online program called THRIVE for breast cancer survivors who struggle with taking their daily hormone-blocking pills. The program aims to boost positive feelings and reduce negative thoughts about the medication. 39 women who had finished primary treatment to…

This study looked at whether Coenzyme Q10, a natural supplement, can help prevent or lessen the side effects of chemotherapy in women with breast cancer. 40 women who had not had chemo before took part. The goal was to see if CoQ10 could reduce problems like fatigue, nerve pain, …

This study tested whether watching 360° virtual reality movies can help lower fear and anxiety in cancer patients before they start radiation treatment. 292 adults with breast, lung, prostate, head and neck cancer, or a brain tumor took part. Researchers measured their stress lev…

This study looked at whether myofascial release exercises (a type of gentle stretching) can help breast cancer patients who have had radiation therapy. 30 women who finished surgery and were about to start radiotherapy took part. The exercises aimed to reduce muscle tightness, pa…

This study tested whether adding ketamine or magnesium sulfate to a standard numbing injection (nerve block) could better control pain after breast cancer surgery. Sixty adults undergoing mastectomy received one of the two add-ons, and researchers measured how much extra morphine…

This study looked at whether giving a lower dose of the steroid dexamethasone before the chemotherapy drug docetaxel is safe for people with breast or prostate cancer. The goal was to reduce steroid side effects like high blood sugar, mood changes, and immune suppression while st…

This study tested whether a shorter course of proton therapy (15 sessions) is as safe as the standard longer course (25 sessions) for women who had a mastectomy for breast cancer and need radiation to nearby lymph nodes. 88 women participated. The goal was to see if the shorter s…

This study tested two different ultrasound-guided nerve blocks to control pain after breast removal surgery (mastectomy) in 64 women aged 35-60. One block targeted the chest wall (PEC I) and the other targeted the side of the ribcage (SAPB). The SAPB block provided better pain re…

This study tested whether a personalized cognitive training program could help breast cancer patients manage 'chemobrain'—memory and thinking problems caused by chemotherapy. Fifty newly diagnosed patients were split into two groups; both received standard advice, but one group a…

This study tested whether wearing special cold caps (Penguin caps) during chemotherapy can prevent or reduce hair loss in people with early-stage breast cancer. Twelve participants used the caps while receiving one of four common chemo regimens. The goal was to see if at least ha…

This study tested whether a special gel (Oleogel-S10) can help heal skin burns caused by radiation therapy in breast cancer patients. The gel was used along with a standard steroid cream. 18 patients with moderate to severe skin reactions took part. The goal was to see if the gel…

This study tested a short, nurse-led program to help breast cancer survivors who were hesitant or delayed in starting hormone therapy. The program aimed to support patients in making informed decisions. The study enrolled 35 women and measured how feasible and acceptable the prog…

This study tested whether starting a personalized exercise program before breast cancer surgery helps women recover better. Thirty female patients followed the program for 12 months. Researchers measured shoulder movement, pain, arm function, fatigue, and quality of life to see i…

This study tested whether omega-3 fatty acid supplements can reduce joint pain and stiffness caused by aromatase inhibitor therapy in postmenopausal women with hormone receptor positive breast cancer. 77 participants took omega-3 supplements soon after starting their cancer medic…

This study looked at whether a program including gentle exercise (Tai Chi), nutritional support, and regular medical check-ups could help women over 70 with breast cancer stick to their hormone therapy. The program aimed to manage side effects like joint pain and vitamin D defici…

This study tested a web-based exercise program for breast cancer patients experiencing nerve pain (peripheral neuropathy) from taxane chemotherapy. 90 patients were split into two groups: one followed the online exercise program for 8 weeks, the other received usual care. The goa…

This study looked at 245 women with early-stage hormone-sensitive breast cancer to see if taking their daily hormone therapy in the morning or evening made a difference in side effects and quality of life. Participants were randomly assigned to take their medication either in the…

This study tested a breast reconstruction method that uses only a patient's own fat (lipomodulin) instead of implants or tissue flaps. It included 118 women who had a mastectomy for breast cancer. The goal was to see how well the technique works, how the breast looks afterward, a…

This study looked at whether a traditional Chinese mind-body exercise called Dao-yin can improve sleep, quality of life, and overall well-being in breast cancer patients who had surgery and are receiving chemotherapy. About 150 women participated, with some doing daily 20-minute …

This study tested whether a noninvasive device that gently stimulates a nerve in the ear (taVNS) could help improve sleep in people with stage I-IV breast cancer. Twenty participants completed the trial, and researchers measured how practical and acceptable the treatment was. The…

This study tested a program called PRISM, designed to help women with breast cancer build resilience through skills like stress management, goal-setting, and positive thinking. 43 women participated, including those with early-stage or metastatic breast cancer. The goal was to se…

This study looked at whether using telemedicine (video calls), connected watches, and symptom tracking apps can help women with advanced breast cancer who live far from their cancer center. Fifteen women took part, and researchers measured their quality of life after 6 and 12 mon…

This study looked at whether physical therapy can improve arm, shoulder, and hand problems that some people develop after breast cancer surgery. It involved 135 women and men who had surgery to remove breast cancer and at least one lymph node. The goal was to see if therapy helps…

This study tested whether eating only during an 8-hour window each day (time-restricted feeding) changes certain blood markers linked to breast cancer risk. Twenty-nine postmenopausal women with prediabetes were randomly assigned to either an 8-hour eating period or a 12-hour or …

This study tested whether a special clinic for women who finished treatment for early-stage breast or gynecologic cancer is practical. About 200 women used an app to report their symptoms, which triggered check-ins from nurses or dietitians when needed. The goal was to see if thi…

This study looked at how Mexican-American families discuss their risk for diabetes, heart disease, breast cancer, and colon cancer. Researchers interviewed 498 adults from Houston-area households to understand how culture and family relationships help or hinder health conversatio…

This study looked at how the hormone therapy tamoxifen affects breast cancer tumors. Researchers examined the interaction between estrogen receptors and a protein called p53 in tumor samples from 59 patients. The goal was to learn more about why some patients respond to tamoxifen…

This study looked at 120 women having mastectomy for breast cancer to see if the gender of their anesthesiologist and the type of pain relief used affected their pain levels and need for painkillers after surgery. Researchers measured pain at 1, 6, 12, and 24 hours after the oper…

This study looked at 200 women with early-stage breast cancer who were taking trastuzumab, a drug that can sometimes harm the heart. Researchers compared two different schedules for checking heart function to see which one works better. The goal was to find the safest and most ef…

This study involved 775 women who had breast-conserving surgery and radiation for breast cancer. Researchers looked at how different combinations of surgery and radiation techniques affected breast firmness (fibrosis) and cosmetic results. The goal was to find ways to improve bot…

This study looked at how physical activity, fitness, and sitting time relate to diabetes risk in 40 female breast cancer survivors taking hormone therapy (aromatase inhibitors or SERMs). Researchers measured insulin resistance, body composition, and exercise capacity. The goal wa…

This study looked at 220 women having breast surgery to see if a blue dye called methylene blue, which is often used to find lymph nodes, affects blood pressure and heart rate during anesthesia. The researchers compared women who got the dye with those who did not. The goal was t…

This study observed over 2,600 women in Germany with advanced HR-positive, HER2-negative breast cancer to see how well different first treatments work in real-world settings. Doctors chose to give either a combination of ribociclib with hormone therapy, hormone therapy alone, or …

This study tested a website and app called BC-Navigate designed to help Black women and other women of color with breast cancer start their chemotherapy on time. Researchers wanted to see if the tool was easy to use and helpful. 64 women who had surgery for early-stage breast can…

This study tested a new automated method to grow cancer cells from patients inside chicken eggs. Researchers used samples from 101 people with metastatic cancers like prostate, breast, and lung cancer. The goal was to see if the automated system could successfully grow tumors at …

This study looked at how much physical activity breast cancer patients in Spain get and what types of exercise they prefer. Researchers surveyed 507 patients using a standard questionnaire to measure activity levels. The goal was to understand current habits and preferences so th…

This study reviewed medical records of 206 people in Egypt with a certain type of advanced breast cancer (HR+/HER2-). Researchers wanted to see how well CDK4/6 inhibitor drugs work in everyday practice, including their benefits, side effects, and cost. The goal was to understand …

This study measured balance and fall risk in 76 postmenopausal women with stage 1-3 breast cancer who had finished chemotherapy. Half were taking aromatase inhibitors for at least a year, and half had never taken them. Researchers used special balance tests and ultrasound to see …

This study looked at how different hormone therapies affect memory in postmenopausal women with breast cancer. 44 women were randomly assigned to take either an aromatase inhibitor (letrozole, anastrozole, or exemestane) or tamoxifen citrate. The main goal was to measure changes …

This study tested whether adding osteopathic manipulative medicine (OMM) to standard breast massage helps more blue dye and radioactive tracer reach the lymph nodes during breast cancer surgery. 27 women having breast-conserving surgery and sentinel lymph node biopsy took part. R…

This study tested a new type of CT scanner that takes pictures while a patient lies on the treatment couch during radiation therapy. 41 adults with head and neck, lung, breast, abdominal, or pelvic cancer participated. The goal was to see if the scanner produces clear images that…

This study looked back at medical records of 42 Japanese patients with a certain type of advanced breast cancer (HR+/HER2-). All patients had been treated with the drugs palbociclib and letrozole in an earlier study. The goal was to see how long they lived after starting treatmen…

This study aimed to find protein patterns (proteomic signatures) in tumor samples and blood that could predict how well breast cancer responds to chemotherapy given before surgery. Researchers analyzed samples from 66 women with breast cancer who had not received prior chemothera…

This study looked at whether it is possible to measure certain cholesterol byproducts, called oxysterols, in the blood of women with breast cancer who are taking hormone therapy like tamoxifen. The study included 29 women and took blood samples before and 28 days after starting t…

This study looked at how 5-FU, a common chemotherapy drug, affects small blood vessels in the skin. Researchers measured blood flow in 62 people, including current and past cancer patients and healthy volunteers. The goal was to better understand why 5-FU can cause heart problems…

This completed pilot study looked at how closely 200 patients with advanced breast or prostate cancer follow their prescribed oral treatments. Participants filled out questionnaires about their medication use and gave blood samples to check certain health markers. The goal was to…

This study looked at nearly 4,500 women to see if finding breast cancer through screening (mammogram) or through symptoms (like a lump) affects quality of life years later. Researchers compared side effects and well-being between these groups, and also compared them to women with…

This study looked at whether a simple blood test can predict which patients are more likely to have long-term side effects from radiation therapy. Researchers measured how well certain immune cells (CD8 T-cells) die after being exposed to radiation. The goal was to see if this te…

This study looked at 595 people in India with a certain type of advanced breast cancer (HR-positive, HER2-negative). Researchers checked for changes in the PIK3CA gene and tracked how patients did on the drug alpelisib. No new treatments were given—doctors made all decisions as u…

This study tested a social platform called MammoChat where people who had breast cancer imaging could share experiences anonymously. Researchers measured anxiety levels and collected de-identified images to train AI for better detection. 199 adults participated, and the goal was …

This study created and tested a short 8-question survey to measure how well women accept their breast cancer diagnosis. Researchers worked with 101 women to see if the survey reliably captures two key aspects: being open to cancer-related thoughts and feelings, and staying active…

This large study looked at over 2 million people with type 2 diabetes to see if those taking dapagliflozin had a different risk of breast or bladder cancer compared to those on other diabetes medications. Researchers tracked cancer cases for up to 12 years. The goal was to unders…

This study tested an artificial intelligence (AI) model to measure heart rhythm changes (QTc interval) in 70 women with breast cancer starting the drug ribociclib. The goal was to see if the AI could match the accuracy of standard ECG monitoring, potentially allowing simpler devi…

This study looked at 172 breast cancer patients to see how two types of radiation therapy—proton and photon—affect heart health. Researchers measured heart function and blood markers before, during, and up to one year after treatment. The goal was to understand which method might…

This study looked at medical records of 1,669 adults with HER2-low breast cancer that had spread or could not be removed by surgery. Researchers wanted to understand how common this type of cancer is and how doctors in Russia actually diagnose and treat it. The goal was to learn …

This study looked at medical records from over 218,000 people in England with a common type of breast cancer (HR+/HER2-). Researchers tracked which treatments patients received, how the disease progressed over time, and how healthcare resources were used. The goal was to better u…

This study reviewed medical records of 111 adults with early-stage HER2-positive breast cancer who received neratinib as an extra treatment after their initial therapy. The goal was to describe the patients' characteristics, such as age, tumor details, and health history. It did …

This study reviewed medical records of over 1,100 breast cancer patients in Japan to understand how they are treated with the drug palbociclib. Researchers looked at how often patients had blood tests and how long they stayed on the medication. The goal was to describe real-world…

This study looked at whether a personalized follow-up schedule is better than standard guidelines for women who finished treatment for early-stage breast cancer. 261 participants were randomly assigned to either a tailored plan or the usual every-3-to-6-month visits. The goal was…

This study tested a new program called REASSURE to help low-risk breast cancer survivors feel more prepared for their follow-up care. About 104 survivors took part for up to 18 months. The program aimed to reduce unnecessary visits while making sure survivors got the care they ne…

This study looked at 236 adults with breast, pancreatic, or colorectal cancer who sought a second opinion at the University of Colorado. Researchers reviewed medical records to understand why some patients stayed for treatment while others did not. The goal is to learn more about…

This study looked at whether a special type of genetic counseling, which uses charts and graphs, helps newly diagnosed breast cancer patients make more informed decisions about surgery. About 400 patients took part. The goal was to see if this method changes how patients understa…

This study looked at women aged 70 and older who finished treatment for early-stage breast cancer within the past two months. Researchers used a special survey to find symptoms and problems the women were having, then shared this information with their doctors to arrange extra he…

This study surveyed 109 men with prostate cancer and women with breast cancer who were starting radiation therapy. Researchers asked about their use of nutritional supplements and complementary or alternative medicine (CAM) at three different times to see if their habits changed.…

This study surveyed 514 breast cancer patients to find out what stops low-income and minority groups from getting genomic testing. Researchers created an online survey and conducted phone interviews to learn about these barriers. The goal is to help make testing more fair and acc…

This study analyzed blood samples from 49 women with metastatic breast cancer to find genetic markers linked to how they respond to trastuzumab (Herceptin). The goal was to better understand side effects like heart toxicity and allergic reactions, as well as treatment effectivene…

This study tested whether adding a drug that targets specific genetic changes in breast tumors before surgery can slow tumor growth better than standard hormone therapy alone. It involved 19 women with ER-positive, HER2-negative breast cancer. The approach aims to personalize tre…

This study looked at 36 people having breast cancer surgery to see how well different numbing techniques block pain. Researchers mapped the numb areas on the skin to understand which method covers the surgical cut best. The goal is to help doctors choose the right pain relief for…

This study tested a community-based program to help homeless women get mammograms for breast cancer screening. Researchers worked with 203 women living in shelters or transitional housing to identify and overcome barriers to screening. The goal was to increase screening rates and…

This study looked at memory complaints in 426 people, including those with brain tumors, breast cancer, and healthy volunteers. Researchers focused on 'prospective memory'—remembering to do things in the future, like taking medication. They found that cancer patients reported mor…

This study tested a combination of chemotherapy (nab-paclitaxel) and immunotherapy (pembrolizumab) given before surgery to 32 people with hormone receptor-positive breast cancer. The main goal was to see if this treatment changes a biomarker called PD-L1 in the tumor. Researchers…

This study worked with healthcare workers, clinic staff, and community members in Soweto, South Africa, to figure out the best ways to offer breast cancer screening using simple physical exams in local clinics. The goal was to understand what makes it easy or hard to do these exa…

This study tested whether a patient navigator could help Black breast and prostate cancer patients complete a shorter course of radiation therapy. 30 African-American adults took part. Researchers used surveys to find out what barriers patients face and whether the navigator help…

This study used functional MRI (fMRI) to see how the brain's sensory map changes after breast reconstruction surgery. Researchers scanned 49 women who had one breast reconstructed after mastectomy. The goal was to objectively measure how the brain responds to touch on the reconst…

This study looked at over 1,500 women with early-stage HER2-positive or triple-negative breast cancer who had no signs of cancer in their lymph nodes on ultrasound. Researchers wanted to see how often cancer actually spread to the lymph nodes after surgery. The goal is to find ou…

This study tested a noninvasive imaging method called DOSI that uses harmless near-infrared light to monitor how breast tumors respond to chemotherapy. Researchers measured changes in oxygen levels in the tumor over time to see if they could predict whether the cancer would be co…

This study tested a new device that detects light signals during breast cancer surgery to help surgeons know what type of tissue they are cutting. 24 women with early-stage breast cancer took part. The main goal was to see if the device is safe and to gather information for futur…

This study tested a digital health platform designed to help people with a genetic mutation for hereditary breast and ovarian cancer communicate test results with their relatives. Researchers worked with 128 participants in Switzerland and Korea to see if the tool could reduce di…

This study tested whether a personalized 6-week psychological intervention could reduce stress and change the biology of breast tumors in 40 women undergoing surgery. Participants were randomly assigned to receive either the psychological program or standard nursing care. Researc…

This study looked at data from 298 breast cancer patients to build a computer model that can predict whether a patient's tumor will completely disappear after chemotherapy given before surgery. The model uses standard medical information like tumor type and patient history. The g…

This study looked at how 830 women with early or locally advanced breast cancer were doing after finishing their main treatment. Researchers used questionnaires to measure quality of life, including physical and emotional health. The goal was to understand survivors' well-being, …

This study looked at why some breast cancer treatments stop working over time. Researchers took tumor samples from 269 patients whose cancer had returned or worsened after targeted therapy. By studying genetic and protein changes in the tumors, they hope to understand resistance …

This study looked at whether a genetic deficiency (DPD deficiency) can predict severe side effects from the chemotherapy drug capecitabine in women with metastatic breast cancer. Researchers analyzed blood samples from 303 participants to see if those with the deficiency experien…

This study looked at whether combining information from electronic health records with data provided directly by patients can create more accurate breast cancer risk predictions. Researchers worked with 70 women at high risk for breast cancer to see if this approach improves risk…

This study looked at whether analyzing proteins in spinal fluid can help identify breast cancer that has spread to the lining of the brain. Seven adults with suspected spread provided fluid samples during their diagnosis. The goal was to learn more about the disease, not to test …

This study looked at how a drug called SAR439859, being tested for breast cancer, is absorbed, broken down, and removed from the body. Six healthy postmenopausal women took a single dose with a radioactive tracer. The goal was to understand the drug's metabolism and bioavailabili…

This study looked at whether a culturally tailored education program, with or without a personal health coach, could help more White Mountain Apache women get mammograms. 323 women took part. The goal was to see if these approaches increased screening within two months of a docto…

This study looked at 300 breast cancer patients who had surgery, chemotherapy, or radiation and developed complications like shoulder stiffness, swelling, or scar tightness. Researchers built a machine-learning model to predict how long rehabilitation would take. The goal is to h…

This study looked at 1,000 women who had breast reconstruction with implants right after mastectomy and also received radiation therapy. Researchers compared two types of implant coverings—polyurethane and non-polyurethane—to see which led to fewer complications like scar tissue …

This study looked at 77 women with breast lesions that only show up on special contrast-enhanced mammograms. Doctors wanted to find out the smallest number of tissue samples needed to make a reliable diagnosis. The goal is to make the biopsy process more efficient and comfortable…

This study looked at how neoadjuvant chemotherapy (chemo given before surgery) affects physical abilities in 67 women with breast cancer. Researchers measured muscle strength, balance, and daily function before and after treatment. The goal was to understand the physical changes …

This study reviewed medical records of 405 adults in Egypt with advanced breast cancer to find out how many had a subtype called HER2-low. Researchers looked at past test results to count cases and describe patient characteristics. The goal was to better understand this group, no…

This study analyzed information from over 5,000 people with early-stage breast cancer who received a specific type of chemotherapy called dose-dense sequential chemotherapy. The goal was to see how long they lived without the cancer coming back and what side effects they had. Thi…

This study checked if olaparib, a drug for advanced ovarian or breast cancer, leads to low folate (folic acid) levels in the blood. Ten postmenopausal women were followed to see how many developed folate deficiency and when it happened. The goal was to understand a possible side …

This study aimed to create a personalized 3D computer model of the breast to help surgeons better understand where tumors are located and plan incisions. Researchers measured skin elasticity and thickness in 200 women, and performed additional MRI scans in different positions for…

This early study tested whether it is safe to temporarily open the blood-brain barrier using focused ultrasound in 8 people with HER2-positive breast cancer that spread to the brain. The goal was to see if the procedure could be done without causing serious side effects. The stud…

This study compared two ways of giving information about fertility preservation to young women (ages 18-40) newly diagnosed with breast cancer who had not yet started treatment. One group received standard face-to-face counseling, while the other used an online decision support t…

This study followed 562 premenopausal women with hormone receptor-positive breast cancer after surgery. Researchers wanted to understand their quality of life and how well they stuck to treatment with GnRHa, a drug that temporarily stops the ovaries from making estrogen. The goal…

This study analyzed blood samples from breast cancer patients to find genetic factors that might predict how well they respond to chemotherapy. Researchers focused on patients who received common chemo drugs like anthracyclines or taxanes. The goal was to identify biomarkers that…

This study looked at whether a special website or two phone calls with a health coach could encourage more people with a personal or family history of certain cancers to get genetic testing. Over 800 adults who already completed a family health survey were randomly assigned to on…

This study looked at 35 women with early-stage breast cancer who normally wouldn't qualify for genetic testing. It compared using an artificial intelligence program for pre-test genetic counseling versus the usual in-person session. The goal was to see if AI could help more women…

This study looked at whether a care plan led by a geriatrician and a trained nurse could improve survival and quality of life for older adults (70+) with advanced cancer. 792 patients with breast, colorectal, lung, prostate, bladder, ovarian cancer, or lymphoma took part. The app…

This study looked at 39 women with advanced breast cancer who were starting hormone therapy (tamoxifen or aromatase inhibitors). Researchers checked their blood for tiny molecules called microRNAs that might show whether the cancer is sensitive or resistant to the treatment. The …

This study looked at whether automated planning tools can be used with MRI scans to guide radiation therapy for breast cancer. The goal was to make treatment faster and more precise without extra radiation exposure. 63 female breast cancer patients participated to help refine thi…

This study looked at whether sentinel lymph node biopsy (a way to check if cancer has spread) works well in women who have more than one tumor in the same breast. 216 women with multifocal breast cancer took part. The main goal was to see how often doctors could find the sentinel…

This early-stage study tested the safety of a new drug called Orialpha (BD-C) in 15 healthy adults aged 18 to 60. Researchers gave increasing doses to find the highest safe amount and watched for side effects. The goal was not to treat any disease, but to gather safety informatio…

This study tested a method to identify immune cells (T cells) that recognize unique mutations in tumors from breast cancer or melanoma patients. Researchers looked at lymph nodes invaded by cancer to see if they could find and measure these cells. The goal was to see if the metho…

This study looked at how breast cancer treatments affect sexual health in women. Researchers followed 25 women who had non-metastatic breast cancer and were referred for fertility preservation. Participants filled out anonymous questionnaires about their sexual function, quality …

This study looked at how breast cancer impacts the quality of life of young women (under 45) and their life partners. Researchers interviewed couples at different times during medical follow-up to understand their experiences. The goal was to create a questionnaire that helps doc…

This study looked at whether giving monthly reimbursements to women with breast cancer in a clinical trial could help with their financial stress. Researchers wanted to see if it was possible to run such a program and if it made a difference. Thirty-nine women from the Deep South…

This study looked at how a gelatin capsule containing American ginseng root extract affects certain substances in breast cancer tumors and nearby healthy breast tissue. Sixteen women with breast cancer took the extract for 10-14 days before their scheduled surgery. Researchers me…

This study looked at 422 breast cancer patients to understand how their knowledge of exercise benefits, their current activity level, and their fatigue affect their beliefs about physical activity and their desire to be active. All participants were undergoing chemotherapy and we…

This study looked back at medical records of women with advanced or metastatic HR+/HER2- breast cancer who received palbociclib combined with hormone therapy in community clinics. The goal was to see how doctors actually prescribe these treatments and what outcomes patients exper…

This study looked at 110 breast cancer patients to see if arm swelling (lymphedema) is linked to a specific type of muscle pain called myofascial pain syndrome. Researchers checked for tender spots in the muscles and measured pain levels. The goal was to understand how these cond…

This study looked at how a common type of chemotherapy (anthracycline) affects blood vessels and blood pressure control in people treated for breast cancer or lymphoma. Researchers measured artery stiffness and blood vessel function in 60 participants, including those currently o…

This study looked at whether a common type of chemotherapy (anthracyclines) for breast cancer makes the heart more sensitive to stress during surgery with general anesthesia. Researchers measured a heart stress marker called BNP in 54 women before, during, and after breast cancer…

This study offered a quick hepatitis C test to 1,500 women aged 50-74 who were already coming in for breast cancer screening. The goal was to see how many women would agree to the extra test and to find undiagnosed hepatitis C cases. Women who tested positive were then guided to …

This study looked at how women ages 39-49 react to scientific evidence about mammography's benefits and harms. Researchers measured feelings like disbelief, distrust, and thinking the information doesn't apply to them. The goal was to understand what influences their choices abou…

This study looked back at medical records of over 500 women in Gulf countries whose breast cancer had spread and was previously labeled as HER2-negative. Researchers re-checked the original tumor samples to find out how many actually had a newer subtype called HER2-low. The goal …

This study looked at 220 women with HER2-low advanced breast cancer whose current treatment stopped working. Researchers reviewed medical records from three hospitals to see which next treatments worked best and were safest. The goal is to help doctors choose the most effective t…

This study looked at whether providing doctors with a free online risk calculator (PREDICT 2.1) changes how often they order a costly genomic test (Oncotype DX) for patients with early-stage breast cancer. About 600 patients took part, and researchers tracked test orders and trea…

This study looked back at the records of 471 women who had breast cancer surgery with immediate breast reconstruction. It compared a newer method using a tiny camera through small cuts (endoscopic surgery) to the traditional method with a larger cut. The goal was to see which app…

This study looked at whether a low-dose vaginal estrogen tablet (Vagifem) is safe for women who have had breast cancer and are taking hormone-blocking drugs called aromatase inhibitors. 31 postmenopausal women with a history of breast cancer used the tablet for vaginal dryness, a…

This study tested whether AI-assisted software can help doctors outline organs at risk during radiation therapy planning for lung, breast, and esophageal cancers. 500 adults scheduled for chest radiation had their CT scans contoured manually, by AI alone, and by AI with manual tw…

This study looked at arm function and oxygen use in 60 women — some who had breast cancer and some who were healthy. Researchers measured how well the arms work during exercise and how muscles use oxygen. The goal was to understand if breast cancer survivors have reduced arm capa…

This study looked at the molecular changes in the skin of 20 breast cancer patients undergoing radiation therapy. The goal was to understand why some patients develop itchy, dry, or red skin (radiation dermatitis). By taking small skin samples, researchers hope to find better way…

This study looks at better ways to measure how tumors respond to treatment before surgery. Researchers compared a new 3D method (TDTP-RECIST) with the standard approach (RECIST 1.1) in 120 adults with breast, pancreatic, or biliary cancers. By reviewing past scans and tumor tissu…

This study tested a program for adults aged 65-90 who had breast, colorectal, or prostate cancer. A community health worker assessed their health and provided coaching to address issues often missed after cancer treatment. The goal was to see if this approach is practical and hel…

This study looked at whether a home body water analyzer can help detect lymphedema early in women treated for breast cancer. Lymphedema is arm swelling caused by fluid buildup, and catching it early is key because early stages are reversible. Researchers followed 52 women for 12 …

This study looked at the sexual health needs of 93 women diagnosed with breast cancer. Researchers wanted to understand how sexual well-being changes during treatment and what educational resources patients currently receive and prefer. The goal was to develop better educational …

This study looked at 50 women with breast cancer who had a lumpectomy. Researchers compared two types of anesthesia—general anesthesia and a nerve block called PECS block—to see how each affected blood cell counts (like white blood cells and platelets) before and after surgery. T…

This study tested a mobile health app designed to help Black or African American women with breast cancer learn about and join clinical trials. Researchers wanted to see if the app was easy to use and helpful for both patients and clinic staff. The study involved 80 women and foc…

This study looked at medical records of 779 older adults (65+) with a common type of advanced breast cancer (HR+/HER2-). It compared those who received a combination of two drugs (palbociclib plus an aromatase inhibitor) versus those who received only one drug (aromatase inhibito…

This study aimed to create a screening tool to identify women at high risk for long-term arm problems—like pain, swelling, and limited movement—after breast cancer surgery and treatments. Researchers followed 1602 women and used questionnaires to measure arm function, pain, and a…

This study looked at whether teaching women in prison about breast cancer helps them know more about it. Forty women took part and filled out surveys before and after the lessons. The goal was to see if the education improved their understanding of symptoms, risks, and self-exams…

This study looked for better ways to detect when breast cancer spreads to the lining of the brain and spinal cord, a condition called leptomeningeal metastases. Researchers collected spinal fluid from 51 patients with suspected spread and compared a new blood-based detection meth…

This study looked at whether a mobile app that teaches about HPV and breast cancer can help women understand HPV better and have more positive feelings about getting screened for breast cancer. Seventy women aged 30-65 used the app and filled out surveys before and after the prog…

This study looked at whether a special PET scan (FDG-PET) can detect early whether breast cancer is responding to chemotherapy. 63 women with breast tumors larger than 2 cm had a PET scan before and after their first chemo cycle. The goal was to see if changes in the scan could i…

This study looked at whether the ratio of index to ring finger length (2D:4D) is different in women with breast cancer compared to healthy women. Researchers measured the fingers of 132 women (79 with breast cancer, 53 without) and checked their blood for tumor markers. The goal …

This study tested whether using artificial intelligence (AI) to help read mammograms could find breast cancer more effectively than the usual method of two radiologists reading each scan. Over 100,000 women took part. The goal was to see if AI could reduce missed cancers and fals…

This study looked at 28 people with breast cancer that spread to the bones. The goal was to see if two types of scans, PET-CT and whole-body MRI, give the same results when checking if treatment is working. The findings could help doctors better decide whether to continue or chan…

This study tested whether a newer type of PET scan (68Ga-FAPI) can better predict how well breast cancer responds to chemotherapy before surgery, compared to standard PET and MRI scans. Twenty-seven women with advanced breast cancer received imaging before and after chemotherapy,…

This study looked at better ways to find breast cancer early in women who have a high genetic risk due to BRCA1 or BRCA2 gene changes. About 200 women aged 25 to 55 took part. They received standard screening plus extra tests like breast MRI and duct lavage to see if these method…

This study tested a website designed to help doctors and women aged 75 to 89 discuss the benefits and drawbacks of mammography screening. 155 participants, including patients and their family members, took part. The goal was to improve shared decision-making, not to treat or prev…

This study observed over 2,400 women in Russia with advanced HR+/HER2- breast cancer who were already receiving standard treatments like ribociclib, alpelisib, hormone therapy, or chemotherapy. Researchers tracked how long each treatment worked before it stopped being effective o…

This study looked at whether a personalized meal plan with more omega-3 fatty acids (found in fish) could help breast cancer survivors manage symptoms like fatigue, pain, depression, and sleep problems. About 98 women who had finished treatment for early-stage breast cancer took …

This study looked at how DNA from tumors changes in the blood before, during, and after cancer surgery. Thirty adults with breast, prostate, or colon cancer had blood samples taken to measure these DNA levels. The goal was to understand the natural changes, not to test a treatmen…

This study looked at 93 women with breast cancer who had a lumpectomy and then received a special type of radiation called simultaneous integrated boost (SIB). The goal was to track any short-term and long-term side effects from this treatment. Researchers compared their results …

This study tested whether breast cancer has a unique smell that can be captured by a special polymer. Researchers collected samples from the hands and tumors of 35 women before and after breast cancer surgery. The goal was to see if a sensitive technique could isolate cancer-rela…

This study tested a device that measures pain signals during breast surgery to see if a nerve block (a type of painkiller) is working correctly. 100 women having a mastectomy took part. The goal was to find a better way to check if the nerve block is effective, which could help d…

This study tested whether sending reminders (nudges) to doctors, patients, or both could increase the number of women with extremely dense breasts who get a breast MRI. Over 1,300 women aged 40-74 took part. The goal was to see if these nudges help catch cancer earlier, especiall…

This study looked at how women aged 65 and older with early-stage breast cancer choose between three treatment options after surgery: standard radiation therapy, a single dose of radiation during surgery, or no radiation at all. Researchers wanted to understand what factors influ…

This study looked at how emotional skills of young women (45 or younger) with non-spreading breast cancer and their partners affect their ability to adjust to the disease. Over 390 couples were followed from chemotherapy through recovery. The goal was to understand how emotions i…

This study looked at 20 breast cancer patients with advanced lymph node involvement to see if a less extensive surgery (targeted axillary dissection) could accurately tell if cancer remained after chemotherapy. The goal was to see if removing fewer lymph nodes could still give do…

This study reviewed medical records of 693 Japanese patients with a certain type of advanced breast cancer (HR+/HER2-) who received palbociclib plus hormone therapy as their first or second treatment. Researchers wanted to see how long patients lived without the cancer getting wo…

This study tested a digital tool (a chatbot) to help cancer survivors learn about genetic testing for hereditary cancer risk. 50 adults who had certain cancers (like breast, ovarian, or prostate) took part. The goal was to see if the chatbot was easy to use and if it helped more …

This study tested a new device called the EnVisio SmartClip that helps doctors locate breast tumors during surgery. Fifty people with breast cancer took part. The goal was to see if the SmartClip makes it easier for radiologists and surgeons to find and remove the right tissue.

This study looked at 171 women with early breast cancer to see if immune cells inside tumors are linked to how well chemotherapy works. Researchers also checked if these immune markers relate to cancer DNA in the blood. The goal is to better understand which patients might respon…

This study tested a new type of CT scanner that takes pictures during radiation therapy for lung, liver, breast, and other cancers. The goal was to see if the new scanner produces clearer images with fewer distortions. 31 people participated, and the results will help doctors bet…

This study looked at whether sending text message reminders could boost the number of people who complete colorectal and breast cancer screening. Over 44,000 eligible adults participated. The goal was to see if simple SMS reminders are more effective than standard letters alone, …

This study looked at how a drug called itraconazole (used for fungal infections) changes the way the body processes HRS-8080, a potential breast cancer treatment. Sixteen healthy adults took HRS-8080 alone and then with itraconazole to measure drug levels and check for side effec…

This study looked at 480 patients with a common type of advanced breast cancer (HR+, HER2-) to see how doctors actually use a class of drugs called CDK4/6 inhibitors in everyday practice. Researchers collected information on patient characteristics, treatment patterns, and outcom…

This study tested a program called KanSurvive-ECHO to help rural primary care clinics provide better follow-up care for cancer survivors. Researchers worked with 15 clinics to improve tasks like scheduling cancer screenings, checking for distress, and tracking weight and tobacco …

This study looked at whether using a special ultrasound ruler during breast-conserving surgery helps surgeons remove all cancer the first time. Researchers reviewed records from 273 breast cancer patients. The goal was to see if this technique lowers the chance of needing a secon…

This study looked at how women aged 39 to 49 make decisions about mammography screening after reading a guide that explains both the benefits and harms. About 500 women completed surveys over a year to share their thoughts, intentions, and whether they actually got screened. The …

This study looked at 70 breast cancer survivors to see how their physical activity levels relate to heart disease risk. Participants wore a special armband to track activity and had their heart risk scored. The goal was to gather information on whether staying active can help pro…

This study tested a new questionnaire to measure quality of life in young women (under 45) with non-metastatic breast cancer and their partners. Over 1000 couples participated by filling out surveys at home. The goal was to see if the questionnaire accurately captures their well-…

This study aimed to develop a questionnaire that measures quality of life specifically for men with breast cancer, since most existing tools focus on women. 65 men with breast cancer participated by rating which issues mattered most to them. The results will help create a validat…

This study looked at how calcium and vitamin levels change in women receiving chemotherapy after breast cancer surgery. 146 patients were followed over 6 treatment cycles. The main goal was to see how often high calcium in urine occurs. This helps doctors better manage side effec…

This study examined how CDK4/6 inhibitors, a type of targeted therapy, are actually used in hospitals across Portugal for advanced or metastatic breast cancer. Researchers looked at data from 16 public hospitals involving nearly 2,000 patients to understand treatment patterns, ho…

This study looked at how a special tumor test, called the 21 gene Recurrence Score (OncotypeDx), affects whether doctors recommend chemotherapy for women with a common type of early-stage breast cancer. Researchers tracked 87 patients in Ireland to see if the test results changed…