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Virus and immune drug combo shows promise against stubborn breast cancer

NCT ID NCT03802604

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 35 times

Summary

This study tested a combination of two drugs—talimogene laherparepvec (T-VEC), a virus that attacks cancer cells, and atezolizumab, an immunotherapy—in 28 women with early-stage breast cancer that still had tumor left after standard chemotherapy. The goal was to see if this combo could shrink or eliminate the remaining cancer before surgery. The trial was early-stage and exploratory, so results are preliminary and not yet a proven treatment.

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Contacts and locations

Locations

  • Centro Integral Oncológico Clara Campal

    Madrid, Madrid, 28050, Spain

  • Hospital Clínic de Barcelona

    Barcelona, 08036, Spain

  • Hospital Clínico universitario de Valencia

    Valencia, Valencia, 46010, Spain

  • Hospital Universitari Vall d'Hebrón

    Barcelona, Barcelona, 08035, Spain

Conditions

Explore the condition pages connected to this study.