Magnetic fields join the fight against breast cancer in first safety trial
NCT ID NCT06332508
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tested whether adding pulsed electromagnetic fields (PEMFs) to standard chemotherapy is safe for people with breast cancer. Fourteen participants received the combination before surgery. The main goal was to check for side effects, not to cure the disease. This study helps pave the way for future research on this potential new treatment approach.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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14 people
The number who actually took part.
- Started
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Dec 2022
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 99 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Histologically confirmed breast carcinoma of any subtype (any estrogen receptor, progesterone receptor and HER2 receptor status) 2. ECOG 0-1. 3. Non-metastatic disease for which surgery of curative intent is planned upfront or after completion of neoadjuvant chemotherapy 4. Adequate organ function including the following: 1. Bone marrow: 1. Absolute neutrophil (segmented and bands) count (ANC) \>= 1.5 x 10\^9/L 2. Platelets \>= 100 x 10\^9/L 3. Hemoglobin \>= 8 x 10\^9/L 2. Hepatic: 1. Bilirubin \<= 1.5 x upper limit of normal (ULN), 2. ALT or AST \<= 2.5x ULN, (or \<=5 X with liver metastases) 3. Renal: 1. Creatinine \<= 1.5x ULN 5. Signed informed consent from subject or legal representative. 6. Able to comply with study-related procedures. Exclusion Criteria: 1. Pregnancy. 2. Breast feeding. 3. Presence of fungating breast tumor or open wound in breast planned for PEMF. 4. Active bleeding disorder or bleeding site. 5. Second primary malignancy that is clinically detectable at the time of consideration for study enrollment. 6. Major surgery within 28 days prior to study administration. 7. Non-healing wound. 8. Active infection that in the opinion of the investigator would compromise the subject's ability to tolerate therapy. 9. History of significant neurological or mental disorder, including seizures or dementia. 10. Serious concomitant disorders that would compromise the safety of the subject or compromise the subject's ability to complete the study, at the discretion of the investigator.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National University Hospital
Singapore, Singapore, 119074, Singapore
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Other studies related to the condition(s) this trial covers.
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