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Antioxidant supplement may ease chemo toxicity in breast cancer

NCT ID NCT06570811

Symptom relief Sponsor: Damanhour University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether taking Coenzyme Q10, a natural antioxidant, can help prevent or reduce side effects from chemotherapy in breast cancer patients. Forty women newly diagnosed with breast cancer and about to start chemotherapy took either Coenzyme Q10 or a placebo. Researchers tracked common side effects like fatigue, nerve damage, nausea, and anemia to see if the supplement made a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Coenzyme Q10 (an antioxidant found in foods and made by the body)
What this could lead to
If it works, this could point toward a way to ease chemotherapy side effects like fatigue, nerve pain, and nausea in breast cancer patients.
What could go wrong
This is a small, early-phase study with only 40 participants. The results may not apply to everyone, and Coenzyme Q10 might not reduce toxicity significantly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

40 people

The number who actually took part.

Started

Aug 2024

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. women with newly diagnosed breast cancer r ≥18 years old. 2. Naive to chemotherapy. 3. Eastern Cooperative Oncology Group (ECOG) performance status from 0-2 Exclusion Criteria: 1. Advanced liver disease (defined as liver enzyme elevation \>3-fold upper limit of normality, or cirrhosis); chronic kidney disease (CKD, defined as an estimated glomerular filtration rate (eGFR) \<60 ml min-1 1.73 m-2). 2. Patients with a history of allergy to Coenzyme Q10 and similar compounds. 3. Concomitant use of opioids, anticonvulsants, tricyclic antidepressants, other neuropathic pain medication. 4. Pregnancy or breast feeding. 5. hereditary muscle disorders.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm chemotherapy-induced toxicity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Chemotherapeutic toxicity

Contacts and locations

Locations

  • Damanhour Oncology Center

    Damanhūr, 22511, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.