Can ketamine cut morphine use after breast cancer surgery?
NCT ID NCT00210210
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at whether giving ketamine during anesthesia can reduce the need for morphine and lower pain after breast cancer surgery. About 230 adults having a mastectomy or lumpectomy took part. The goal was to see if ketamine helps avoid morphine's side effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ketamine
- What this could lead to
- If effective, ketamine could help reduce the need for morphine and its side effects after breast cancer surgery.
- What could go wrong
- This trial is already completed and results may not show a strong benefit. Ketamine can cause side effects like hallucinations or confusion.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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230 people
The number who actually took part.
- Started
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Jan 2004
- Finished
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Dec 2005
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 100 years
- Sex
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Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * Patients 18 years older * ASA class 1 or 2 * with surgery of breast cancer (mastectomy or tumorectomy) Exclusion criteria: .Kétamine hypersensitivity * Major psychiatric disorders * Major cardio-vascular disorders * Major neurologic disorders * Major ocular disorders * Morphine in pre-operative period
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Institut Bergonié - Centre Régional de Luttre Contre le Cancer de Bordeaux et du Sud Ouest
Bordeaux, 33076, France
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