No-Needle cancer test: ultrasound reads tumor type
NCT ID NCT07581054
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new way to tell breast cancer types apart using a special ultrasound, instead of a tissue biopsy. Researchers looked at blood vessel patterns in tumors from 94 patients and built a tool to predict whether the cancer was luminal or non-luminal. The goal is to help doctors choose the best treatment without needing to take a sample from the tumor.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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94 people
The number who actually took part.
- Started
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May 2025
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
A total of 94 consecutive patients with histologically confirmed invasive breast cancer who underwent super-resolution ultrasound (SRUS) at the First Affiliated Hospital of USTC (Anhui Provincial Cancer Hospital) between May 2025 and January 2026 were included. All patients had available immunohistochemical data for molecular subtyping (ER, PR, HER2, Ki-67) according to the St. Gallen criteria. The cohort comprised 64 patients with luminal subtype and 30 patients with non-luminal subtype. Key demographic and clinical characteristics (age, tumor size, menopausal status) were balanced between the two groups.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Age ≥ 18 years Histologically confirmed invasive breast cancer Underwent super-resolution ultrasound (SRUS) examination between May 2025 and January 2026 Available immunohistochemical data (estrogen receptor, progesterone receptor, HER2, and Ki-67) for molecular subtyping according to the St. Gallen International Expert Consensus Exclusion Criteria: Prior treatment for ipsilateral breast cancer Pregnancy or lactation Severe cardiac, hepatic, or renal insufficiency Psychiatric disorder Inadequate ultrasound image quality precluding reliable SRUS reconstruction
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Anhui Provincial Cancer Hospital
Hefei, Anhui, 230001, China
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Other studies related to the condition(s) this trial covers.
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