New hope for BRCA breast cancer: targeted chemo shows promise in trial
NCT ID NCT01670500
First seen May 17, 2026 · Last updated May 24, 2026 · Updated 2 times
Summary
This study tested whether the chemotherapy drug cisplatin works better than a standard combination (doxorubicin and cyclophosphamide) for women with newly diagnosed breast cancer who carry a BRCA gene mutation. 118 women participated, receiving one of the two treatments before surgery. The main goal was to see which drug more effectively eliminated all signs of cancer in the breast tissue removed during surgery.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Duke University
Durham, North Carolina, 27708, United States
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Georgetown University Medical Center
Washington D.C., District of Columbia, 20007, United States
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Johns Hopkins
Baltimore, Maryland, 21287, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08901, United States
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Sibley Memorial Hospital
Washington D.C., District of Columbia, 20016-2698, United States
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Smilow Cancer Hospital Care Center at Derby
Derby, Connecticut, 06418, United States
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Smilow Cancer Hospital Care Center at Guilford
Guilford, Connecticut, 06437, United States
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St. Francis Hospital and Medical Center
Hartford, Connecticut, 06105, United States
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University of Colorado Cancer Center
Aurora, Colorado, 80045, United States
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Women and Infants Hospital
Providence, Rhode Island, 02905, United States
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Yale School of Medicine
New Haven, Connecticut, 06520, United States
Conditions
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