Beth Israel Deaconess Medical Center

This study tests if adding a second drug (raloxifene) to a standard BPH medication (finasteride) works better than finasteride alone. About 242 men with an enlarged prostate will take pills daily for 12 months. The goal is to see if the combination improves urinary symptoms more …

This study tests whether the drug epcoritamab can help people with follicular lymphoma whose cancer did not completely go away after standard first treatment. About 35 adults with advanced-stage lymphoma will receive epcoritamab as a second-line therapy. The goal is to see if the…

This study is testing whether getting healthy groceries delivered to your home, along with help from a dietitian, can lower blood pressure in people with high blood pressure. Researchers in Florida, Georgia, and Tennessee are looking for 150 adults with elevated blood pressure. P…

This study tests whether using remote alerts from heart devices (like pacemakers or defibrillators) can improve care compared to standard doctor visits. About 120 adults with these devices will be randomly assigned to either alert-driven care or usual care. The goal is to see if …

This study looks at whether people who had a brain hemorrhage (bleeding stroke) should keep taking statins or stop them. It includes 1,456 adults aged 50 and older who were on statins before their stroke. Researchers will also check if a person's genes affect the best choice. The…

This study compares high flow oxygen to standard oxygen in 1,600 adults with dangerously low blood oxygen (acute hypoxemia) at five hospitals in East Africa. The goal is to see which method reduces deaths and uses oxygen more efficiently. Participants are randomly assigned to rec…

This study tests whether doctor-modified grafts can safely repair complex aortic aneurysms and dissections in patients who cannot use standard devices. About 220 high-risk adults will receive a custom-fitted graft during a minimally invasive procedure. Researchers will track surv…

This study tests whether surgically completing the gaps between lung lobes before placing one-way valves can improve lung volume reduction in people with severe emphysema or COPD. About 20 participants will either receive the combined procedure or standard medical care. The goal …

This study is testing a handheld device called the mScan that uses a tiny, painless electrical current to measure muscle health. Researchers will compare its results to MRI scans in 150 adults with and without muscle diseases like muscular dystrophy or myositis. If successful, th…

This study tests whether mind-body techniques can reduce symptoms like pain, fatigue, and dizziness in people with Long COVID. About 180 adults will be randomly assigned to one of two mind-body programs or to usual care. Researchers will measure changes in symptom severity and da…

This study tests a new, non-invasive treatment for people with drug-resistant epilepsy, whose seizures are not controlled by medication. The treatment uses infrared light, which has reduced seizures in animal studies. Researchers want to see if daily light therapy is safe, tolera…

This pilot study tests whether injecting a small amount of sterile saltwater through a thin spinal catheter can quickly reverse leg weakness caused by spinal anesthesia. About 20 adults having elective hip or knee replacement surgery will receive the saline flush after their oper…

This study tests whether a gentle, non-invasive brain stimulation technique called HD-tDCS can help people with traumatic brain injury (TBI) find words more easily. About 24 adults with a TBI at least one year ago will receive either real or fake stimulation during word and memor…

This study tests whether a CPAP machine, commonly used for sleep apnea, can help people with excessive central airway collapse (ECAC) breathe better and walk farther. Researchers will compare CPAP to a sham device in 32 adults over 3 months. The main goal is to see if CPAP improv…

This study tests a decision aid for women aged 70 and older with early-stage, low-risk breast cancer. The tool helps them and their doctors discuss treatment options, aiming to reduce aggressive treatments like mastectomy or radiation when they may not be needed. About 402 partic…

This study tests whether letting men control their own nitrous oxide (laughing gas) during a vasectomy reduces pain and anxiety. About 35 men scheduled for vasectomy will use a self-adjusted mask. The goal is to see if this approach improves comfort and satisfaction during the pr…

This study tests a new way to improve sleep in people with mild cognitive impairment (MCI). It combines a gentle brain stimulation technique (transcranial magnetic stimulation) with cognitive behavioral therapy for insomnia. The goal is to see if this approach can improve sleep q…

This early-stage study tests a mind-body program for people with chronic migraines. Ten adults with frequent headaches will try remote relaxation and coping techniques. The main goal is to see if the approach is practical and to pick the best ways to measure any changes in pain a…

This study tests a mind-body approach to help people with long-term wrist, elbow, or shoulder pain from repetitive stress injuries. Researchers want to see if it improves arm function and reduces pain. About 40 adults will participate in this early-stage pilot trial.

This study tests a new rehabilitation program for people who lost part of their vision after a stroke. The program combines visual training with mild electrical stimulation on the brain to try to speed up recovery. Researchers will enroll 24 adults with stroke-related vision loss…

This study looks at why postmenopausal women have a higher chance of developing diastolic heart failure (a type of heart failure where the heart stiffens). Researchers will examine heart tissue from 500 patients having heart surgery to see how estrogen loss affects certain protei…

This early-phase study looks at how heat stress changes the body's chemistry, especially in the kidneys, and whether vitamin B3 (niacinamide) can influence that response. Researchers will test 28 healthy, physically fit volunteers under different heat conditions. The goal is to u…

This study tests a new program called Doula Link, which gives doulas extra training and resources to support the mental health of pregnant and new parents. About 90 doulas and their clients will take part. The goal is to see if the program is practical and liked, and if it might …

This study is testing a device called the mScan, which uses a gentle electrical current to measure muscle health in people with ALS. The goal is to see if this device can track how the disease progresses over time better than current methods. About 80 participants will use the de…

This study looks at brown fat, a special type of fat that burns energy and may help control metabolism. Researchers will collect small fat samples from 40 healthy adults during planned surgeries. The goal is to learn how brown and white fat differ, which could lead to new ways to…

This study uses special dye and scans to map the lymphatic system in the arms of healthy women and breast cancer survivors who did not develop swelling. The goal is to understand normal anatomy and how it may change after cancer treatment. Results may help prevent lymphedema in t…

This study looks at whether a 15-minute meditation practice called Shoonya can help people stay sharp and focused after a night of poor sleep. Researchers will compare regular meditators, people who nap, and those who do neither. The goal is to see if meditation changes sleep pat…

This study looks at whether pregnant women with high-risk conditions like diabetes or high blood pressure can use a remote fetal monitor at home instead of going to the clinic. Fifty participants will use the device for 30-minute sessions three times a week starting at 32 weeks o…

This study looks at whether transferring embryos after 3 days or 5 days of growth leads to more live births in IVF patients who have only a few embryos. About 1,126 women with 5 or fewer embryos will be randomly assigned to one of the two transfer times. The goal is to help docto…

This study looks at how quickly the stomach empties in women during early labor when they drink either water or a carbohydrate sports drink. Researchers want to see if the type of drink or having an epidural changes stomach emptying time. About 108 pregnant women at 36 weeks or m…

This study looks at whether a 21-minute daily meditation practice called Shambhavi Mahamudra Kriya can improve brain health. Researchers will measure brain activity, brain structure, and thinking skills in 80 adults aged 20-65 over 6 months. The goal is to understand how meditati…