Dry needling vs. placebo: which really soothes knots in your neck?
NCT ID NCT07270276
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether dry needling can reduce pain from trigger points (tight, tender spots) in the trapezius muscle, which runs from the neck to the shoulders. About 70 adults with myofascial pain will receive either dry needling or a placebo treatment. Researchers will use special muscle tests and daily pain surveys to see if the treatment works.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Aug 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ages 18-80 * Presence of active trigger points with involvement of upper trapezius * Able to manage breakthrough pain with acetaminophen only, excluding stable doses of pain medications at time of enrollment, which can be continued Exclusion Criteria: * Multiple active trigger points in the trapezius muscle if physician assessment concludes that this may interfere with subject's ability to detect changes in pain improvement from trigger point therapy * Presence of cervical radicular pain, superimposed neuromuscular disease or condition that, in the opinion of the investigator, could confound interpretation of the data acquired from trapezius. * Fibromyalgia or other generalized pain condition * Opioid usage in the past 3 months * Active substance use disorder * Not on a stable dose for at least two weeks prior to study enrollment or unwilling to maintain a stable dose for duration of the study of the following drugs: 1. SSRIs, such as citalopram, escitalopram, fluoxetine, sertraline, 2. SNRIs, such as duloxetine, milnacipran, and venlafaxine 3. Tricyclic antidepressants, such as notritptyline, amitriptyline, and desipramine 4. Alpha 2 delta ligands: pregabalin, gabapentin 5. Specific anti-epileptics: topiramate, lamotrigine, oxcarbazepine, and phenytoin 6. Other: quinidine, mexiletine, and dalfampridine * Skin allergy or sensitivity that would preclude the use of adhesive electrodes * Significant systemic or psychiatric illness that in the opinion of the site Investigator would interfere with the individual's ability to participate in the trial * Anticoagulation (with coumadin, clopidogrel, or direct oral anticoagulants; aspirin acceptable) * TrP needle-based therapy in the past six weeks of the TrP to be studied * Body mass index \> 35 kg/m2 * Other factor that in the opinion of the site investigator would interfere with the ability to perform the study procedures
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
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Massachusetts General Hospital
NOT_YET_RECRUITINGBoston, Massachusetts, 02114, United States
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