New study tests best shot for stubborn neck pain
NCT ID NCT07547605
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests three types of injections for people with chronic neck and shoulder muscle pain caused by trigger points. It compares platelet-rich plasma (PRP), a mix of PRP and steroid, and steroid alone to see which works best. 150 adults aged 18-65 with a single active trigger point will be followed for 6 months. The goal is to find the most effective treatment for reducing pain and improving movement.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 18 and 65 years * Presentation to the Orthopedics and Traumatology outpatient clinic with neck and/or shoulder pain * Diagnosis of upper trapezius myofascial pain syndrome based on Simons and Travell criteria, including: * Presence of a taut band * Local tenderness * Referred pain pattern * Local twitch response * Presence of a single active trigger point in the upper trapezius muscle * Symptom duration ≥ 4 weeks * Pain intensity ≥ 4 on the visual analog scale (VAS) * Inadequate response to at least 4 weeks of conservative treatment (physical therapy and/or oral analgesics) * Ability to provide written informed consent Exclusion Criteria: * Presence of multiple active trigger points * Diagnosis of fibromyalgia according to ACR 2010 criteria * Cervical radiculopathy or myelopathy * Trigger point injection in the same region within the past 3 months * Coagulopathy or current anticoagulant or antiplatelet therapy * Known allergy or contraindication to corticosteroids, local anesthetics, or PRP components * Active infection (systemic or local) * Pregnancy or lactation * Thrombocytopenia (platelet count \< 100,000/µL) * Malignancy * Inability to cooperate or provide informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Dr. Suat Gunsel University of Kyrenia Hospital
RECRUITINGKyrenia, Keryneia, 6000, Cyprus
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Dr. Suat Gunsel University of Kyrenia Hospital
RECRUITINGKyrenia, 6000, Cyprus
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