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New surgical fix may help emphysema patients when valves fail

NCT ID NCT05257681

First seen Apr 18, 2026 · Last updated Jun 22, 2026 · Updated 8 times

Summary

This pilot study tests a surgical procedure for people with severe emphysema or COPD who did not get enough benefit from a standard valve treatment. The surgery uses small incisions to complete the fissures between lung lobes and remove scar tissue, aiming to improve lung function. The study will enroll 20 participants to see if the procedure is feasible and safe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

surgical procedure (video-assisted thoracoscopic surgery or robotic stapling along lung fissures with adhesion removal)

What this could lead to

If it works, this could offer a salvage option for emphysema patients who didn't benefit from a less invasive valve procedure, potentially improving breathing and quality of life.

What could go wrong

This is a very small pilot study (20 people) testing a new surgical approach. It may not work for everyone, and there are risks of serious complications from surgery, including infection or breathing problems.

Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease pulmonary emphysema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.