Beth Israel Deaconess Medical Center

This study tests two different drugs—dexrazoxane and liposomal doxorubicin—to see which is safer and more effective at preventing heart failure in people with a type of lymphoma called DLBCL. All 60 participants will receive standard chemotherapy (R-CHOP or pola-R-CHP), and the g…

Sepsis damages the protective lining of blood vessels, leading to organ failure and death. This study tests whether giving fresh frozen plasma—either as short infusions or continuously—can repair that lining better than a placebo fluid. About 45 adults with sepsis in the ICU will…

This study tests a new way to care for people with pacemakers or defibrillators. Instead of routine checkups, doctors will only see patients when the device sends a specific alert. The goal is to see if this alert-driven approach is safer and more effective than standard care. Ab…

This pilot study will test whether an iPad app called DCog Short can spot early signs of brain-related side effects (neurotoxicity) in 40 adults receiving CAR-T cell therapy for blood cancers. Participants will use the app to self-report symptoms, and researchers will compare the…

This study tests whether simple breathing exercises and guided meditations can reduce stress, anxiety, and depression in elderly ICU survivors (over 60) and their caregivers. Participants will practice these techniques using a mobile app or in a group, and will also wear a safe E…

This trial tests whether giving high-flow nasal oxygen before, during, and after robotic surgery can prevent dangerous drops in oxygen levels and reduce lung complications. About 190 adults having long robotic surgeries will be randomly assigned to receive either high-flow nasal …

This study tests whether applying lidocaine gel to the vagina before placing a cervical ripening balloon can reduce pain during labor induction. About 110 pregnant women at 37 weeks or later will take part. Researchers will compare pain scores between those who get the gel and th…

This study looks at whether adding a short daily guided meditation practice to mindfulness education can improve how engaged and well employees feel at work. About 134 adult workers will use a smartphone app and complete surveys over 12 weeks. The goal is to see if the combined a…

This study tests whether a short, daily meditation app can help young adults feel better, less stressed, and more resilient. About 354 people aged 18-40 in the US will be randomly assigned to do a 7-minute meditation, listen to a neutral audio, or continue their normal routine fo…

This study looks at how irregular sleep and certain types of lighting affect thinking skills and brain health. Researchers will monitor 40 healthy adults aged 18-40 to measure changes in sleep, mental performance, and brain chemistry. The goal is to understand these connections, …

This study looks at how changing the pressure on a breathing machine (called PEEP) affects the heart's pumping ability in adults during heart surgery. Researchers will monitor 28 participants using ultrasound and other tools to measure heart function at different pressure levels.…

This study looks at whether a meditation program called Inner Engineering can help teens ages 15-18 become more joyful, focused, and resilient. Researchers will measure changes in emotional wellbeing, stress, and even brain activity using surveys, body sensors, and brain scans. T…

This study tests a special microscope that lets surgeons check for leftover cancer cells right after removing the prostate. About 20 men with prostate cancer will have their removed tissue scanned during surgery. The goal is to see if this method works well and can help surgeons …